Genetics of rheumatoid arthritis contributes to biology and drug discovery Y Okada, D Wu, G Trynka, T Raj, C Terao, K Ikari, Y Kochi, K Ohmura, ... Nature 506 (7488), 376-381, 2014 | 2253 | 2014 |
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations JZ Liu, S Van Sommeren, H Huang, SC Ng, R Alberts, A Takahashi, ... Nature genetics 47 (9), 979-986, 2015 | 2122 | 2015 |
Defining the role of common variation in the genomic and biological architecture of adult human height AR Wood, T Esko, J Yang, S Vedantam, TH Pers, S Gustafsson, AY Chu, ... Nature genetics 46 (11), 1173-1186, 2014 | 1978 | 2014 |
Systematic identification of trans eQTLs as putative drivers of known disease associations HJ Westra, MJ Peters, T Esko, H Yaghootkar, C Schurmann, J Kettunen, ... Nature genetics 45 (10), 1238-1243, 2013 | 1801 | 2013 |
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 CA Anderson, G Boucher, CW Lees, A Franke, M D'Amato, KD Taylor, ... Nature genetics 43 (3), 246-252, 2011 | 1593 | 2011 |
New genetic loci link adipose and insulin biology to body fat distribution D Shungin, TW Winkler, DC Croteau-Chonka, T Ferreira, AE Locke, ... Nature 518 (7538), 187-196, 2015 | 1444 | 2015 |
Genome-wide association study identifies 74 loci associated with educational attainment A Okbay, JP Beauchamp, MA Fontana, JJ Lee, TH Pers, CA Rietveld, ... Nature 533 (7604), 539-542, 2016 | 1277 | 2016 |
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses A Okbay, BML Baselmans, JE De Neve, P Turley, MG Nivard, MA Fontana, ... Nature genetics 48 (6), 624-633, 2016 | 971 | 2016 |
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment CA Rietveld, SE Medland, J Derringer, J Yang, T Esko, NW Martin, ... science 340 (6139), 1467-1471, 2013 | 949 | 2013 |
Biological interpretation of genome-wide association studies using predicted gene functions TH Pers, JM Karjalainen, Y Chan, HJ Westra, AR Wood, J Yang, JC Lui, ... Nature communications 6 (1), 5890, 2015 | 785 | 2015 |
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis S Eyre, J Bowes, D Diogo, A Lee, A Barton, P Martin, A Zhernakova, ... Nature genetics 44 (12), 1336-1340, 2012 | 707 | 2012 |
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci D Ellinghaus, L Jostins, SL Spain, A Cortes, J Bethune, B Han, YR Park, ... Nature genetics 48 (5), 510-518, 2016 | 657 | 2016 |
The transcriptional landscape of age in human peripheral blood MJ Peters, R Joehanes, LC Pilling, C Schurmann, KN Conneely, J Powell, ... Nature communications 6 (1), 1-14, 2015 | 531 | 2015 |
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences R Karlsson Linnér, P Biroli, E Kong, SFW Meddens, R Wedow, ... Nature genetics 51 (2), 245-257, 2019 | 503 | 2019 |
Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ... BioRxiv, 447367, 2018 | 473 | 2018 |
Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus W Yang, N Shen, DQ Ye, Q Liu, Y Zhang, XX Qian, N Hirankarn, D Ying, ... PLoS genetics 6 (2), e1000841, 2010 | 446 | 2010 |
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ... Nature genetics 53 (9), 1300-1310, 2021 | 430 | 2021 |
Trans-eQTLs Reveal That Independent Genetic Variants Associated with a Complex Phenotype Converge on Intermediate Genes, with a Major Role for the HLA RSN Fehrmann, RC Jansen, JH Veldink, HJ Westra, D Arends, ... PLoS genetics 7 (8), e1002197, 2011 | 416 | 2011 |
Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci A Zhernakova, EA Stahl, G Trynka, S Raychaudhuri, EA Festen, L Franke, ... PLoS genetics 7 (2), e1002004, 2011 | 404 | 2011 |
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals GB Ehret, T Ferreira, DI Chasman, AU Jackson, EM Schmidt, T Johnson, ... Nature genetics 48 (10), 1171-1184, 2016 | 401 | 2016 |