Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging K Young, E Eudy, R Bell, MA Loberg, T Stearns, D Sharma, L Velten, ... Cell stem cell, 2021 | 126 | 2021 |
Sequentially inducible mouse models reveal that Npm1 mutation causes malignant transformation of Dnmt3a-mutant clonal hematopoiesis MA Loberg, RK Bell, LO Goodwin, E Eudy, LA Miles, JM SanMiguel, ... Leukemia 33 (7), 1635-1649, 2019 | 107 | 2019 |
Distinct Tumor Necrosis Factor Alpha Receptors Dictate Stem Cell Fitness versus Lineage Output in Dnmt3a-Mutant Clonal Hematopoiesis JM SanMiguel, E Eudy, MA Loberg, KA Young, JJ Mistry, KD Mujica, ... Cancer discovery 12 (12), 2763-2773, 2022 | 49 | 2022 |
Trapping redox partnerships in oxidant-sensitive proteins with a small, thiol-reactive cross-linker KM Allan, MA Loberg, J Chepngeno, JE Hurtig, S Tripathi, MG Kang, ... Free Radical Biology and Medicine 101, 356-366, 2016 | 20 | 2016 |
Piecing together how peroxiredoxins maintain genomic stability J West, T Roston, J David, K Allan, M Loberg Antioxidants 7 (12), 177, 2018 | 18 | 2018 |
Cell origin–dependent cooperativity of mutant Dnmt3a and Npm1 in clonal hematopoiesis and myeloid malignancy JM SanMiguel, E Eudy, MA Loberg, LA Miles, T Stearns, JJ Mistry, ... Blood Advances 6 (12), 3666-3677, 2022 | 13 | 2022 |
Cell-extrinsic stressors from the aging Bone Marrow (BM) microenvironment promote Dnmt3a-mutant clonal hematopoiesis JM SanMiguel, M Loberg, S Heuer, T Stearns, K Young, J Trowbridge Blood 134 (Supplement_1), 5-5, 2019 | 13 | 2019 |
Aromatic Residues at the Dimer− Dimer Interface in the Peroxiredoxin Tsa1 Facilitate Decamer Formation and Biological Function MA Loberg, JE Hurtig, AH Graff, KM Allan, JA Buchan, MK Spencer, ... Chemical research in toxicology 32 (3), 474-483, 2019 | 12 | 2019 |
Wnt signaling in the phenotype and function of tumor-associated macrophages ML Tigue, MA Loberg, JA Goettel, WA Weiss, E Lee, VL Weiss Cancer Research 83 (1), 3-11, 2023 | 7 | 2023 |
Heritable genetic background alters survival and phenotype of Mll-AF9-induced leukemias K Young, MA Loberg, E Eudy, LS Schwartz, KD Mujica, JJ Trowbridge Experimental hematology 89, 61-67. e3, 2020 | 6 | 2020 |
The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling VH Ng, Z Spencer, LR Neitzel, A Nayak, MA Loberg, C Shen, SN Kassel, ... Nature Communications 14 (1), 6173, 2023 | 5 | 2023 |
Molecular signature incorporating the immune microenvironment enhances thyroid cancer outcome prediction GJ Xu, MA Loberg, JN Gallant, Q Sheng, SC Chen, BD Lehmann, ... Cell Genomics 3 (10), 2023 | 3 | 2023 |
Hematopoietic stem and progenitor cell aging is initiated at middle age through decline in local insulin-like growth factor 1 (IGF1) K Young, E Eudy, R Bell, M Loberg, T Stearns, L Velten, S Haas, ... bioRxiv, 2020 | 3 | 2020 |
Dnmt3a Mutation Confers a Selective Advantage Specifically to Cells within the Long-Term Hematopoietic Stem Cell (LT-HSC) Compartment E Eudy, M Loberg, R Bell, T Stearns, J Trowbridge Blood, The Journal of the American Society of Hematology 134 (Supplement_1 …, 2019 | 3 | 2019 |
Decline in Insulin-like Growth Factor-1 (IGF1) from Aged Mesenchymal Stromal Cells Is a Targetable Mechanism to Rescue Hematopoietic Stem Cell Aging K Young, E Eudy, M Loberg, R Bell, J Trowbridge Blood, The Journal of the American Society of Hematology 134 (Supplement_1 …, 2019 | 3 | 2019 |
Evolving approaches in paediatric thyroid cytopathology: A review MA Loberg, ML Tigue, JN Gallant, H Wang, S Canberk, VL Weiss Cytopathology, 2023 | 2 | 2023 |
Mutation in DNA Methyltransferase DNMT3A Confers Enhanced Self-Renewal Capacity Onto Multipotent Progenitor Cells and Predisposes to Acute Myeloid Leukemia (AML) M Loberg, R Bell, T Stearns, L Goodwin, K Young, D Bergstrom, ... Blood 132 (Supplement 1), 2569-2569, 2018 | 1 | 2018 |
The Middle-Aged Bone Marrow Microenvironment Drives Hematopoietic Stem Cell Aging through Altered Production of Insulin-like Growth Factor-1 (IGF1) K Young, M Loberg, E Eudy, R Bell, JJ Trowbridge Blood 132 (Supplement 1), 5091-5091, 2018 | 1 | 2018 |
Decreased IGF-1 Expression in the Bone Marrow Microenvironment Drives Hematopoietic Aging K Young, M Loberg, R Bell, JJ Trowbridge Blood 130 (Supplement 1), 2440-2440, 2017 | 1 | 2017 |
Transcriptomic Analysis Identifies a Subset of BRAF-Like Thyroid Cancers at Risk for Future Poor Outcome M Loberg, G Xu, SC Chen, Q Sheng, E Huang, F Ye, V Weiss Journal of the American Society of Cytopathology 11 (6), S64, 2022 | | 2022 |