Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice D Lindén, A Ahnmark, P Pingitore, E Ciociola, I Ahlstedt, AC Andréasson, ... Molecular metabolism 22, 49-61, 2019 | 216 | 2019 |
Human multilineage 3D spheroids as a model of liver steatosis and fibrosis P Pingitore, K Sasidharan, M Ekstrand, S Prill, D Lindén, S Romeo International journal of molecular sciences 20 (7), 1629, 2019 | 132 | 2019 |
Chebulagic acid from Terminalia chebula enhances insulin mediated glucose uptake in 3T3‐L1 adipocytes via PPARγ signaling pathway GL Shyni, S Kavitha, S Indu, AD Arya, SS Anusree, VP Vineetha, ... BioFactors 40 (6), 646-657, 2014 | 43 | 2014 |
Discovery and Targeting of the Signaling Controls of PNPLA3 to Effectively Reduce Transcription, Expression, and Function in Pre-Clinical NAFLD/NASH Settings BE Schwartz, V Rajagopal, C Smith, E Cohick, G Whissell, M Gamboa, ... Cells 9 (10), 2247, 2020 | 40 | 2020 |
PSD3 downregulation confers protection against fatty liver disease RM Mancina, K Sasidharan, A Lindblom, Y Wei, E Ciociola, ... Nature metabolism 4 (1), 60-75, 2022 | 31 | 2022 |
Licarin B from Myristica fragrans improves insulin sensitivity via PPARγ and activation of GLUT4 in the IRS-1/PI3K/AKT pathway in 3T3-L1 adipocytes GL Shyni, K Sasidharan, SK Francis, AA Das, MS Nair, KG Raghu Rsc Advances 6 (83), 79859-79870, 2016 | 25 | 2016 |
Molecular analysis of three known and one novel LPL variants in patients with type I hyperlipoproteinemia A Caddeo, RM Mancina, C Pirazzi, C Russo, K Sasidharan, J Sandstedt, ... Nutrition, Metabolism and Cardiovascular Diseases 28 (2), 158-164, 2018 | 15 | 2018 |
Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice. Mol Metab. 2019; 22: 49–61 D Linden, A Ahnmark, P Pingitore, E Ciociola, I Ahlstedt, AC Andreasson, ... | 10 | 2019 |
Mitochondrial amidoxime‐reducing component 1 p. Ala165Thr increases protein degradation mediated by the proteasome T Dutta, K Sasidharan, E Ciociola, G Pennisi, FR Noto, L Kovooru, ... Liver International 44 (5), 1219-1232, 2024 | 6 | 2024 |
IL32 downregulation lowers triglycerides and type I collagen in di-lineage human primary liver organoids K Sasidharan, A Caddeo, O Jamialahmadi, FR Noto, M Tomasi, ... Cell Reports Medicine 5 (1), 2024 | 5 | 2024 |
MARC1 downregulation reduces hepatocyte lipid content by increasing beta-oxidation E Ciociola, T Dutta, K Sasidharan, L Kovooru, FR Noto, G Pennisi, S Petta, ... Clinical and molecular hepatology, 2024 | | 2024 |
Translational genetics identifies a novel target to treat fatty liver disease K Sasidharan | | 2023 |
Downregulation of interleukin 32 reduce intracellular triglyceride levels in liver spheroids K Sasidharan, AM Caddeo, O Jamialahmadi, G Baselli, F Malvestiti, ... Atherosclerosis 331, e143, 2021 | | 2021 |
Response to letter to the editor regarding ‘Mitochondrial amidoxime‐reducing component 1 p. Ala165Thr increases protein degradation mediated by the proteasome’ T Dutta, K Sasidharan, D Lindén, S Romeo Liver International, 0 | | |
SUPPORTING MATERIALS AND METHODS Generation of Pnpla3 I148M knock-in mice D Lindén, A Ahnmark, P Pingitore, E Ciociola, I Ahlstedt, AC Andréasson, ... | | |