| Epidermal growth factor receptor (EGFR) and EGFR mutations, function and possible role in clinical trials BR Voldborg, L Damstrup, M Spang-Thomsen, HS Poulsen Annals of Oncology 8 (12), 1197-1206, 1997 | 627 | 1997 |
| The human secretome M Uhlén, MJ Karlsson, A Hober, AS Svensson, J Scheffel, D Kotol, ... Science signaling 12 (609), eaaz0274, 2019 | 331 | 2019 |
| A consensus genome-scale reconstruction of Chinese hamster ovary cell metabolism H Hefzi, KS Ang, M Hanscho, A Bordbar, D Ruckerbauer, M Lakshmanan, ... Cell systems 3 (5), 434-443. e8, 2016 | 245 | 2016 |
| Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion JM Gutierrez, A Feizi, S Li, TB Kallehauge, H Hefzi, LM Grav, D Ley, ... Nature communications 11 (1), 68, 2020 | 108 | 2020 |
| Multiplex secretome engineering enhances recombinant protein production and purity S Kol, D Ley, T Wulff, M Decker, J Arnsdorf, S Schoffelen, AH Hansen, ... Nature communications 11 (1), 1908, 2020 | 90 | 2020 |
| Glyco-engineered CHO cell lines producing alpha-1-antitrypsin and C1 esterase inhibitor with fully humanized N-glycosylation profiles T Amann, AH Hansen, S Kol, HG Hansen, J Arnsdorf, S Nallapareddy, ... Metabolic Engineering 52, 143-152, 2019 | 59 | 2019 |
| In vitro invasion of small-cell lung cancer cell lines correlates with expression of epidermal growth factor receptor L Damstrup, B Rude Voldborg, M Spang-Thomsen, N Brünner, ... British journal of cancer 78 (5), 631-640, 1998 | 58 | 1998 |
| Independent component analysis of E. coli's transcriptome reveals the cellular processes that respond to heterologous gene expression J Tan, AV Sastry, KS Fremming, SP Bjørn, A Hoffmeyer, S Seo, ... Metabolic Engineering 61, 360-368, 2020 | 45 | 2020 |
| Predictive glycoengineering of biosimilars using a Markov chain glycosylation model PN Spahn, AH Hansen, S Kol, BG Voldborg, NE Lewis Biotechnology journal 12 (2), 1600489, 2017 | 43 | 2017 |
| Biochemical characterization of human gluconokinase and the proposed metabolic impact of gluconic acid as determined by constraint based metabolic network analysis N Rohatgi, TK Nielsen, SP Bjørn, I Axelsson, G Paglia, BG Voldborg, ... PloS one 9 (6), e98760, 2014 | 37 | 2014 |
| Whole-genome sequencing of invasion-resistant cells identifies laminin α2 as a host factor for bacterial invasion XM Van Wijk, S Döhrmann, BM Hallström, S Li, BG Voldborg, BX Meng, ... MBio 8 (1), 10.1128/mbio. 02128-16, 2017 | 33 | 2017 |
| Discovery and optimization of a broadly-neutralizing human monoclonal antibody against long-chain α-neurotoxins from snakes L Ledsgaard, J Wade, TP Jenkins, K Boddum, I Oganesyan, JA Harrison, ... Nature Communications 14 (1), 682, 2023 | 30 | 2023 |
| High throughput generation of a resource of the human secretome in mammalian cells H Tegel, M Dannemeyer, S Kanje, Å Sivertsson, A Berling, AS Svensson, ... New biotechnology 58, 45-54, 2020 | 27 | 2020 |
| Assessing developability early in the discovery process for novel biologics ML Fernández-Quintero, A Ljungars, F Waibl, V Greiff, JT Andersen, ... MAbs 15 (1), 2171248, 2023 | 26 | 2023 |
| SSX2 is a novel DNA-binding protein that antagonizes polycomb group body formation and gene repression MF Gjerstorff, MM Relster, KBV Greve, JB Moeller, D Elias, JN Lindgreen, ... Nucleic acids research 42 (18), 11433-11446, 2014 | 25 | 2014 |
| Recognition determinants for proteins and antibiotics within 23S rRNA S Douthwaite, B Voldborg, LH Hansen, G Rosendahl, B Vester Biochemistry and cell biology 73 (11-12), 1179-1185, 1995 | 24 | 1995 |
| A Markov model of glycosylation elucidates isozyme specificity and glycosyltransferase interactions for glycoengineering C Liang, AWT Chiang, AH Hansen, J Arnsdorf, S Schoffelen, ... Current research in biotechnology 2, 22-36, 2020 | 22 | 2020 |
| Screening of genetic parameters for soluble protein expression in Escherichia coli E Vernet, A Kotzsch, B Voldborg, M Sundström Protein Expression and Purification 77 (1), 104-111, 2011 | 18 | 2011 |
| Combating viral contaminants in CHO cells by engineering innate immunity AWT Chiang, S Li, BP Kellman, G Chattopadhyay, Y Zhang, CC Kuo, ... Scientific reports 9 (1), 8827, 2019 | 16 | 2019 |
| The human secretome–the proteins secreted from human cells M Uhlen, H Tegel, Å Sivertsson, CC Kuo, JM Gutierrez, NE Lewis, ... BioRxiv, 465815, 2018 | 16 | 2018 |
