Electric field-driven strategy for multiplexed detection of protein biomarkers using a disposable reagentless electrochemical immunosensor array J Wu, Y Yan, F Yan, H Ju Analytical chemistry 80 (15), 6072-6077, 2008 | 152 | 2008 |
Ultrasensitive characterization of charge heterogeneity of therapeutic monoclonal antibodies using strong cation exchange chromatography coupled to native mass spectrometry Y Yan, AP Liu, S Wang, TJ Daly, N Li Analytical chemistry 90 (21), 13013-13020, 2018 | 105 | 2018 |
Fast photochemical oxidation of proteins (FPOP) maps the epitope of EGFR binding to adnectin Y Yan, G Chen, H Wei, RYC Huang, J Mo, DL Rempel, AA Tymiak, ... Journal of the American Society for Mass Spectrometry 25 (12), 2084-2092, 2014 | 100 | 2014 |
Disposable reagentless electrochemical immunosensor array based on a biopolymer/sol-gel membrane for simultaneous measurement of several tumor markers J Wu, F Yan, X Zhang, Y Yan, J Tang, H Ju Clinical chemistry 54 (9), 1481-1488, 2008 | 87 | 2008 |
Isomerization and oxidation in the complementarity-determining regions of a monoclonal antibody: a study of the modification–structure–function correlations by hydrogen … Y Yan, H Wei, Y Fu, S Jusuf, M Zeng, R Ludwig, SR Krystek Jr, G Chen, ... Analytical chemistry 88 (4), 2041-2050, 2016 | 84 | 2016 |
A Molecular Code for Identity in the Vomeronasal System X Fu, Y Yan, PS Xu, I Geerlof-Vidavsky, W Chong, ML Gross, TE Holy Cell 163 (2), 313–323, 2015 | 57 | 2015 |
Coupling mixed-mode size exclusion chromatography with native mass spectrometry for sensitive detection and quantitation of homodimer impurities in bispecific IgG Y Yan, T Xing, S Wang, TJ Daly, N Li Analytical chemistry 91 (17), 11417-11424, 2019 | 49 | 2019 |
Characterization of product-related low molecular weight impurities in therapeutic monoclonal antibodies using hydrophilic interaction chromatography coupled with mass spectrometry S Wang, AP Liu, Y Yan, TJ Daly, N Li Journal of Pharmaceutical and Biomedical Analysis 154, 468-475, 2018 | 42 | 2018 |
Characterization of adeno-associated virus capsid proteins using hydrophilic interaction chromatography coupled with mass spectrometry AP Liu, SK Patel, T Xing, Y Yan, S Wang, N Li Journal of pharmaceutical and biomedical analysis 189, 113481, 2020 | 41 | 2020 |
Online coupling of analytical hydrophobic interaction chromatography with native mass spectrometry for the characterization of monoclonal antibodies and related products Y Yan, T Xing, S Wang, TJ Daly, N Li Journal of Pharmaceutical and Biomedical Analysis 186, 113313, 2020 | 37 | 2020 |
Versatile, sensitive, and robust native LC–MS platform for intact mass analysis of protein drugs Y Yan, T Xing, S Wang, N Li Journal of the American Society for Mass Spectrometry 31 (10), 2171-2179, 2020 | 36 | 2020 |
Simple approach for improved LC–MS analysis of protein biopharmaceuticals via modification of desolvation gas S Wang, T Xing, AP Liu, Z He, Y Yan, TJ Daly, N Li Analytical chemistry 91 (4), 3156-3162, 2019 | 29 | 2019 |
Analysis of SecA dimerization in solution AJ Wowor, Y Yan, SM Auclair, D Yu, J Zhang, ER May, ML Gross, ... Biochemistry 53 (19), 3248-3260, 2014 | 22 | 2014 |
Coupling anion exchange chromatography with native mass spectrometry for charge heterogeneity characterization of monoclonal antibodies AP Liu, Y Yan, S Wang, N Li Analytical chemistry 94 (16), 6355-6362, 2022 | 18 | 2022 |
High-energy collision-induced dissociation by MALDI TOF/TOF causes charge-remote fragmentation of steroid sulfates Y Yan, M Ubukata, RB Cody, TE Holy, ML Gross Journal of The American Society for Mass Spectrometry 25 (8), 1404-1411, 2014 | 18 | 2014 |
A rapid and simple method for ultrasensitive electrochemical immunoassay of protein by an electric field-driven strategy F Yan, J Wu, F Tan, Y Yan, H Ju Analytica chimica acta 644 (1-2), 36-41, 2009 | 16 | 2009 |
Hydrogen Deuterium Exchange Mass Spectrometry Reveals Unique Conformational and Chemical Transformations Occurring upon [4Fe-4S] Cluster Binding in the Type 2 L-Serine … Y Yan, GA Grant, ML Gross Biochemistry 54 (34), 5322–5328, 2015 | 14 | 2015 |
“De-novo” amino acid sequence elucidation of protein G′ e by combined “Top-Down” and “Bottom-Up” mass spectrometry Y Yefremova, M Al-Majdoub, KFM Opuni, C Koy, W Cui, Y Yan, ML Gross, ... Journal of The American Society for Mass Spectrometry 26 (3), 482-492, 2015 | 13 | 2015 |
Mass spectrometry combinations for structural characterization of sulfated-steroid metabolites Y Yan, DL Rempel, TE Holy, ML Gross Journal of the American Society for Mass Spectrometry 25 (5), 869-879, 2014 | 13 | 2014 |
Mapping the binding interface in a noncovalent size variant of a monoclonal antibody using native mass spectrometry, hydrogen–deuterium exchange mass spectrometry, and … Y Yan, H Wei, S Jusuf, SR Krystek Jr, J Chen, G Chen, RT Ludwig, L Tao, ... Journal of Pharmaceutical Sciences 106 (11), 3222-3229, 2017 | 10 | 2017 |