| Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells M Daher, R Basar, E Gokdemir, N Baran, N Uprety, AK Nunez Cortes, ... Blood, The Journal of the American Society of Hematology 137 (5), 624-636, 2021 | 196 | 2021 |
| AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines L Zhang, JA Zuris, R Viswanathan, JN Edelstein, R Turk, B Thommandru, ... Nature communications 12 (1), 3908, 2021 | 101 | 2021 |
| Optimized design parameters for CRISPR Cas9 and Cas12a homology-directed repair MS Schubert, B Thommandru, J Woodley, R Turk, S Yan, G Kurgan, ... Scientific Reports 11 (1), 19482, 2021 | 74 | 2021 |
| Gene replacement of α-globin with β-globin restores hemoglobin balance in β-thalassemia-derived hematopoietic stem and progenitor cells MK Cromer, J Camarena, RM Martin, BJ Lesch, CA Vakulskas, NM Bode, ... Nature medicine 27 (4), 677-687, 2021 | 66 | 2021 |
| Bioprospecting of Native Efflux Pumps To Enhance Furfural Tolerance in Ethanologenic Escherichia coli G Kurgan, LA Panyon, Y Rodriguez-Sanchez, E Pacheco, LM Nieves, ... Applied and environmental microbiology 85 (6), e02985-18, 2019 | 46 | 2019 |
| Pharmacological interventions enhance virus-free generation of TRAC-replaced CAR T cells J Kath, W Du, A Pruene, T Braun, B Thommandru, R Turk, ML Sturgeon, ... Molecular Therapy-Methods & Clinical Development 25, 311-330, 2022 | 40 | 2022 |
| Large-scale GMP-compliant CRISPR-Cas9–mediated deletion of the glucocorticoid receptor in multivirus-specific T cells R Basar, M Daher, N Uprety, E Gokdemir, A Alsuliman, E Ensley, G Ozcan, ... Blood advances 4 (14), 3357-3367, 2020 | 32 | 2020 |
| CRISPECTOR provides accurate estimation of genome editing translocation and off-target activity from comparative NGS data I Amit, O Iancu, A Levy-Jurgenson, G Kurgan, MS McNeill, GR Rettig, ... Nature communications 12 (1), 3042, 2021 | 29 | 2021 |
| CRISPAltRations: a validated cloud-based approach for interrogation of double-strand break repair mediated by CRISPR genome editing G Kurgan, R Turk, H Li, N Roberts, GR Rettig, AM Jacobi, L Tso, ... Molecular Therapy-Methods & Clinical Development 21, 478-491, 2021 | 21 | 2021 |
| Efficiency, specificity and temperature sensitivity of Cas9 and Cas12a RNPs for DNA-free genome editing in plants R Banakar, M Schubert, G Kurgan, KM Rai, SF Beaudoin, ... Frontiers in Genome Editing 3, 760820, 2022 | 20 | 2022 |
| Emerging tools, enabling technologies, and future opportunities for the bioproduction of aromatic chemicals M Machas, G Kurgan, AK Jha, A Flores, A Schneider, S Coyle, ... Journal of Chemical Technology & Biotechnology 94 (1), 38-52, 2019 | 16 | 2019 |
| Engineering transport systems for microbial production M Onyeabor, R Martinez, G Kurgan, X Wang Advances in Applied Microbiology 111, 33-87, 2020 | 14 | 2020 |
| Shuttle peptide delivers base editor RNPs to rhesus monkey airway epithelial cells in vivo K Kulhankova, S Traore, X Cheng, H Benk-Fortin, S Hallée, M Harvey, ... Nature communications 14 (1), 8051, 2023 | 11 | 2023 |
| Identification of major malate export systems in an engineered malate-producing Escherichia coli aided by substrate similarity search G Kurgan, L Kurgan, A Schneider, M Onyeabor, Y Rodriguez-Sanchez, ... Applied microbiology and biotechnology 103, 9001-9011, 2019 | 11 | 2019 |
| Parallel experimental evolution reveals a novel repressive control of GalP on xylose fermentation in Escherichia coli G Kurgan, C Sievert, A Flores, A Schneider, T Billings, L Panyon, C Morris, ... Biotechnology and bioengineering 116 (8), 2074-2086, 2019 | 11 | 2019 |
| Comparative analysis of CRISPR off-target discovery tools following ex vivo editing of CD34+ hematopoietic stem and progenitor cells MK Cromer, KR Majeti, GR Rettig, K Murugan, GL Kurgan, NM Bode, ... Molecular Therapy 31 (4), 1074-1087, 2023 | 10 | 2023 |
| Optimized design parameters for CRISPR Cas9 and Cas12a homology-directed repair. Sci Rep 11: 19482 MS Schubert, B Thommandru, J Woodley, R Turk, S Yan, G Kurgan, ... | 9 | 2021 |
| Genetically corrected RAG2-SCID human hematopoietic stem cells restore V(D)J-recombinase and rescue lymphoid deficiency M Pavel-Dinu, CL Gardner, Y Nakauchi, T Kawai, OM Delmonte, ... Blood Advances 8 (7), 1820-1833, 2024 | 8 | 2024 |
| Homology-independent targeted insertion (HITI) enables guided CAR knock-in and efficient clinical scale CAR-T cell manufacturing H Balke-Want, V Keerthi, N Gkitsas, AG Mancini, GL Kurgan, C Fowler, ... Molecular Cancer 22 (1), 100, 2023 | 8 | 2023 |
| Characterizing Escherichia coli’s transcriptional response to different styrene exposure modes reveals novel toxicity and tolerance insights M Machas, G Kurgan, OA Abed, A Shapiro, X Wang, D Nielsen Journal of Industrial Microbiology and Biotechnology 48 (1-2), kuab019, 2021 | 8 | 2021 |
