| Omecamtiv mecarbil enhances the duty ratio of human β-cardiac myosin resulting in increased calcium sensitivity and slowed force development in cardiac muscle AM Swenson, W Tang, CA Blair, CM Fetrow, WC Unrath, MJ Previs, ... Journal of Biological Chemistry 292 (9), 3768-3778, 2017 | 95 | 2017 |
| Modulating beta-cardiac myosin function at the molecular and tissue levels W Tang, CA Blair, SD Walton, A Málnási-Csizmadia, KS Campbell, ... Frontiers in physiology 7, 659, 2017 | 27 | 2017 |
| FRET and optical trapping reveal mechanisms of actin activation of the power stroke and phosphate release in myosin V LK Gunther, JA Rohde, W Tang, JA Cirilo, CP Marang, BD Scott, ... Journal of Biological Chemistry 295 (51), 17383-17397, 2020 | 24 | 2020 |
| Dilated cardiomyopathy mutation in the converter domain of human cardiac myosin alters motor activity and response to omecamtiv mecarbil W Tang, WC Unrath, R Desetty, CM Yengo Journal of Biological Chemistry 294 (46), 17314-17325, 2019 | 23 | 2019 |
| Converter domain mutations in myosin alter structural kinetics and motor function LK Gunther, JA Rohde, W Tang, SD Walton, WC Unrath, DV Trivedi, ... Journal of Biological Chemistry 294 (5), 1554-1567, 2019 | 23 | 2019 |
| Cardiomyopathy mutations impact the actin-activated power stroke of human cardiac myosin W Tang, J Ge, WC Unrath, R Desetty, CM Yengo Biophysical journal 120 (11), 2222-2236, 2021 | 20 | 2021 |
| Nanosurfer assay dissects β-cardiac myosin and cardiac myosin-binding protein C interactions AM Touma, W Tang, DV Rasicci, D Vang, A Rai, SB Previs, DM Warshaw, ... Biophysical journal 121 (12), 2449-2460, 2022 | 9 | 2022 |
| Allosteric inhibition of HTRA1 activity by a conformational lock mechanism to treat age-related macular degeneration S Gerhardy, M Ultsch, W Tang, E Green, JK Holden, W Li, A Estevez, ... Nature Communications 13 (1), 5222, 2022 | 5 | 2022 |
| Inter‐filament co‐operativity is crucial for regulating muscle contraction W Tang, CM Yengo The Journal of Physiology 596 (1), 17, 2018 | 2 | 2018 |
| FRET and Optical Trapping Measurements Reveal Relationship between Phosphate Release and the Power Stroke in Myosin V EP Debold, LK Gunther, M Unger, B Scott, W Tang, CM Yengo Biophysical Journal 118 (3), 177a, 2020 | 1 | 2020 |
| Cardiomyopathy Mutations in the Converter Domain of Human Beta-Cardiac Myosin Impairs Mechanochemistry in the Presence and Absence of Load W Tang, SD Walton, WC Unrath, CM Yengo Biophysical Journal 112 (3), 120a, 2017 | 1 | 2017 |
| Cystine-knot peptide inhibitors of HTRA1 bind to a cryptic pocket within the active site region Y Li, Y Wei, M Ultsch, W Li, W Tang, B Tombling, X Gao, Y Dimitrova, ... Nature Communications 15 (1), 4359, 2024 | | 2024 |
| Dissecting β-Cardiac Myosin and Cardiac Myosin-Binding Protein C Interactions using a Nanosurf Assay AM Touma, W Tang, DV Rasicci, D Vang, A Rai, SB Previs, DM Warshaw, ... bioRxiv, 2022.03. 11.483820, 2022 | | 2022 |
| Dissecting cardiac myosin-binding protein C interactions on a synthetic β-cardiac myosin DNA nanotube thick filament AM Touma, D Vang, W Tang, D Rasicci, A Rai, SB Previs, DM Warshaw, ... Biophysical Journal 121 (3), 257a, 2022 | | 2022 |
| Cardiomyopathy Mutations Impact the Power Stroke of Human Cardiac Myosin W Tang, J Ge, WC Unrath, R Desetty, CM Yengo bioRxiv, 2020.12. 08.416511, 2020 | | 2020 |
| Impact of Regulatory Light Chain Mutation (K104E) on the Atpase and Motor Properties of Human Cardiac Myosin D Rasicci, O Kirkland, W Tang, R Desetty, CM Yengo Biophysical Journal 118 (3), 425a, 2020 | | 2020 |
| FRET Measurements of the Power Stroke in Human Cardiac Myosin W Tang, J Ge, R Dessety, CM Yengo Biophysical Journal 118 (3), 7a, 2020 | | 2020 |
| The S217A Mutant Slows the Power Stroke and Phosphate Release in Myosin V LK Gunther, W Tang, CM Yengo Biophysical Journal 116 (3), 260a, 2019 | | 2019 |
| Impact of Human Beta-Cardiac Myosin Mutation Implicated in Both Hypertrophic and Dilated Cardiomyopathy W Tang, LK Gunther, J Cooper, R Desetty, CM Yengo Biophysical Journal 116 (3), 263a-264a, 2019 | | 2019 |
| Mutations in the Converter Domain of Myosin V Demonstrate Coupling Between Lever Arm Swing and Phosphate Release LK Gunther, SD Walton, W Tang, WC Unrath, D Trivedi, CM Yengo Biophysical Journal 114 (3), 321a, 2018 | | 2018 |
