| The role of protein clearance mechanisms in organismal ageing and age-related diseases D Vilchez, I Saez, A Dillin Nature communications 5 (1), 5659, 2014 | 684 | 2014 |
| RPN-6 determines C. elegans longevity under proteotoxic stress conditions D Vilchez, I Morantte, Z Liu, PM Douglas, C Merkwirth, APC Rodrigues, ... Nature 489 (7415), 263-268, 2012 | 436 | 2012 |
| Mechanism suppressing glycogen synthesis in neurons and its demise in progressive myoclonus epilepsy D Vilchez, S Ros, D Cifuentes, L Pujadas, J Vallès, B García-Fojeda, ... Nature neuroscience 10 (11), 1407-1413, 2007 | 433 | 2007 |
| Increased proteasome activity in human embryonic stem cells is regulated by PSMD11 D Vilchez, L Boyer, I Morantte, M Lutz, C Merkwirth, D Joyce, B Spencer, ... Nature 489 (7415), 304-308, 2012 | 414 | 2012 |
| The mechanistic links between proteasome activity, aging and agerelated diseases I Saez, D Vilchez Current genomics 15 (1), 38-51, 2014 | 343 | 2014 |
| Regulation of glycogen synthesis by the laforin–malin complex is modulated by the AMP-activated protein kinase pathway MC Solaz-Fuster, JV Gimeno-Alcañiz, S Ros, ME Fernandez-Sanchez, ... Human molecular genetics 17 (5), 667, 2008 | 164 | 2008 |
| Proteostasis and aging of stem cells D Vilchez, MS Simic, A Dillin Trends in cell biology 24 (3), 161-170, 2014 | 158 | 2014 |
| The autophagy receptor p62/SQST-1 promotes proteostasis and longevity in C. elegans by inducing autophagy C Kumsta, JT Chang, R Lee, EP Tan, Y Yang, R Loureiro, EH Choy, ... Nature Communications 10 (1), 5648, 2019 | 97 | 2019 |
| The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington’s disease patients S Koyuncu, I Saez, HJ Lee, R Gutierrez-Garcia, W Pokrzywa, A Fatima, ... Nature communications 9 (1), 2886, 2018 | 96 | 2018 |
| Somatic increase of CCT8 mimics proteostasis of human pluripotent stem cells and extends C. elegans lifespan A Noormohammadi, A Khodakarami, R Gutierrez-Garcia, HJ Lee, ... Nature communications 7 (1), 13649, 2016 | 86 | 2016 |
| Rewiring of the ubiquitinated proteome determines ageing in C. elegans S Koyuncu, R Loureiro, HJ Lee, P Wagle, M Krueger, D Vilchez Nature 596 (7871), 285-290, 2021 | 75 | 2021 |
| A post-transcriptional program coordinated by CSDE1 prevents intrinsic neural differentiation of human embryonic stem cells H Ju Lee, D Bartsch, C Xiao, S Guerrero, G Ahuja, C Schindler, ... Nature communications 8 (1), 1456, 2017 | 73 | 2017 |
| DNAJB6, a key factor in neuronal sensitivity to amyloidogenesis A Thiruvalluvan, EP de Mattos, JF Brunsting, R Bakels, D Serlidaki, ... Molecular cell 78 (2), 346-358. e9, 2020 | 66 | 2020 |
| Proteostasis of huntingtin in health and disease S Koyuncu, A Fatima, R Gutierrez-Garcia, D Vilchez International journal of molecular sciences 18 (7), 1568, 2017 | 60 | 2017 |
| The ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes MM Rinschen, P Bharill, X Wu, P Kohli, MJ Reinert, O Kretz, I Saez, ... Human molecular genetics 25 (7), 1328-1344, 2016 | 59 | 2016 |
| Insights into the ubiquitin-proteasome system of human embryonic stem cells I Saez, S Koyuncu, R Gutierrez-Garcia, C Dieterich, D Vilchez Scientific reports 8 (1), 4092, 2018 | 50 | 2018 |
| Mechanisms of protein homeostasis (proteostasis) maintain stem cell identity in mammalian pluripotent stem cells A Noormohammadi, G Calculli, R Gutierrez-Garcia, A Khodakarami, ... Cellular and Molecular Life Sciences 75, 275-290, 2018 | 50 | 2018 |
| FOXO 4 is necessary for neural differentiation of human embryonic stem cells D Vilchez, L Boyer, M Lutz, C Merkwirth, I Morantte, C Tse, B Spencer, ... Aging cell 12 (3), 518-522, 2013 | 48 | 2013 |
| Embryonic stem cells: a novel paradigm to study proteostasis? HJ Lee, R Gutierrez‐Garcia, D Vilchez The FEBS journal 284 (3), 391-398, 2017 | 40 | 2017 |
| Systemic regulation of mitochondria by germline proteostasis prevents protein aggregation in the soma of C. elegans G Calculli, HJ Lee, K Shen, U Pham, M Herholz, A Trifunovic, A Dillin, ... Science advances 7 (26), eabg3012, 2021 | 38 | 2021 |
seda koyuncuPostdoctoral researcher在 uni-koeln.de 的电子邮件经过验证
