Variation matters: TLR structure and species-specific pathogen recognition D Werling, OC Jann, V Offord, EJ Glass, TJ Coffey Trends in immunology 30 (3), 124-130, 2009 | 322 | 2009 |
LRRfinder: a web application for the identification of leucine-rich repeats and an integrative Toll-like receptor database V Offord, TJ Coffey, D Werling Developmental & Comparative Immunology 34 (10), 1035-1041, 2010 | 92 | 2010 |
Anti‐apolipoprotein A‐1 IgG in patients with myocardial infarction promotes inflammation through TLR2/CD14 complex S Pagano, N Satta, D Werling, V Offord, P De Moerloose, E Charbonney, ... Journal of internal medicine 272 (4), 344-357, 2012 | 86 | 2012 |
Combinatorial CRISPR screen identifies fitness effects of gene paralogues NA Thompson, M Ranzani, L van der Weyden, V Iyer, V Offord, A Droop, ... Nature communications 12 (1), 1302, 2021 | 81 | 2021 |
Association of frequent moisturizer use in early infancy with the development of food allergy MR Perkin, K Logan, T Marrs, S Radulovic, J Craven, RJ Boyle, ... Journal of Allergy and Clinical Immunology 147 (3), 967-976. e1, 2021 | 75 | 2021 |
Species-specific PAMP recognition by TLR2 and evidence for species-restricted interaction with Dectin-1 S Willcocks, V Offord, HM Seyfert, TJ Coffey, D Werling Journal of Leukocyte Biology 94 (3), 449-458, 2013 | 49 | 2013 |
LRRfinder2. 0: a webserver for the prediction of leucine-rich repeats V Offord, D Werling Innate Immunity 19 (4), 398-402, 2013 | 41 | 2013 |
Determination of genetic variations of Toll-like receptor (TLR) 2, 4, and 6 with next-generation sequencing in native cattle breeds of Anatolia and Holstein Friesian N Bilgen, B Cinar Kul, V Offord, D Werling, O Ertugrul Diversity 8 (4), 23, 2016 | 24 | 2016 |
CRISPR activation screen in mice identifies novel membrane proteins enhancing pulmonary metastatic colonisation L van der Weyden, V Harle, G Turner, V Offord, V Iyer, A Droop, ... Communications biology 4 (1), 395, 2021 | 15 | 2021 |
Dynamic changes in gene expression and signalling during trophoblast development in the horse JE Read, V Cabrera-Sharp, V Offord, SM Mirczuk, SP Allen, RC Fowkes, ... Reproduction 156 (4), 313-330, 2018 | 14 | 2018 |
The Transcriptome of Schistosoma mansoni Developing Eggs Reveals Key Mediators in Pathogenesis and Life Cycle Propagation Z Lu, G Sankaranarayanan, KA Rawlinson, V Offord, PJ Brindley, ... Frontiers in tropical diseases 2, 713123, 2021 | 13 | 2021 |
Two TIR-like domain containing proteins in a newly emerging zoonotic Staphylococcus aureus strain sequence type 398 are potential virulence factors by … NJ Patterson, J Günther, AJ Gibson, V Offord, TJ Coffey, G Splitter, I Monk, ... Frontiers in Microbiology 5, 662, 2014 | 13 | 2014 |
Replacement of two aminoacids in the bovine Toll-like receptor 5 TIR domain with their human counterparts partially restores functional response to flagellin A Osvaldova, S Woodman, N Patterson, V Offord, D Mwangi, AJ Gibson, ... Developmental & Comparative Immunology 47 (1), 90-94, 2014 | 10 | 2014 |
Global gene expression profiling of myeloid immune cell subsets in response to in vitro challenge with porcine circovirus 2b B Mavrommatis, V Offord, R Patterson, M Watson, T Kanellos, F Steinbach, ... PLoS One 9 (3), e91081, 2014 | 10 | 2014 |
Silencing of essential genes within a highly coordinated operon in Escherichia coli S Goh, A Hohmeier, TC Stone, V Offord, F Sarabia, C Garcia-Ruiz, L Good Applied and Environmental Microbiology 81 (16), 5650-5659, 2015 | 9 | 2015 |
Potential evidence for biotype-specific chemokine profile following BVDV infection of bovine macrophages S Burr, C Thomas, J Brownlie, V Offord, TJ Coffey, D Werling Veterinary Immunology and Immunopathology 150 (1-2), 123-127, 2012 | 9 | 2012 |
Variant Library Annotation Tool (VaLiAnT): an oligonucleotide library design and annotation tool for Saturation Genome Editing and other Deep Mutational Scanning experiments L Barbon, V Offord, EJ Radford, AP Butler, SS Gerety, DJ Adams, HK Tan, ... Bioinformatics 38 (4), 892-899, 2022 | 8 | 2022 |
HIRA loss transforms FH-deficient cells L Valcarcel-Jimenez, C Rogerson, C Yong, C Schmidt, M Yang, ... Science advances 8 (42), eabq8297, 2022 | 7 | 2022 |
Structural characterisation of Toll-like receptor 1 (TLR1) and Toll-like receptor 6 (TLR6) in elephant and harbor seals S Woodman, AJ Gibson, AR García, GS Contreras, JW Rossen, D Werling, ... Veterinary Immunology and Immunopathology 169, 10-14, 2016 | 6 | 2016 |
Membrane protein regulators of melanoma pulmonary colonization identified using a CRISPRa screen and spontaneous metastasis assay in mice L van der Weyden, V Offord, G Turner, A Swiatkowska, AO Speak, ... G3 11 (7), jkab157, 2021 | 4 | 2021 |