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Isabel Moraes
Isabel Moraes
Google DeepMind
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Membrane protein structure determination—the next generation
I Moraes, G Evans, J Sanchez-Weatherby, S Newstead, PDS Stewart
Biochimica et Biophysica Acta (BBA)-Biomembranes 1838 (1), 78-87, 2014
3082014
Lipidic cubic phase serial millisecond crystallography using synchrotron radiation
P Nogly, D James, D Wang, TA White, N Zatsepin, A Shilova, G Nelson, ...
IUCrJ 2 (2), 168-176, 2015
2422015
In situ macromolecular crystallography using microbeams
D Axford, RL Owen, J Aishima, J Foadi, AW Morgan, JI Robinson, ...
Acta Crystallographica Section D: Biological Crystallography 68 (5), 592-600, 2012
1482012
Structure of a lipid A phosphoethanolamine transferase suggests how conformational changes govern substrate binding
A Anandan, GL Evans, K Condic-Jurkic, ML O’Mara, CM John, NJ Phillips, ...
Proceedings of the National Academy of Sciences 114 (9), 2218-2223, 2017
1352017
High-throughput stability screening for detergent-solubilized membrane proteins
V Kotov, K Bartels, K Veith, I Josts, UKT Subhramanyam, C Günther, ...
Scientific reports 9 (1), 10379, 2019
1252019
The structure of mammalian serine racemase: evidence for conformational changes upon inhibitor binding
MA Smith, V Mack, A Ebneth, I Moraes, B Felicetti, M Wood, D Schonfeld, ...
Journal of Biological Chemistry 285 (17), 12873-12881, 2010
972010
The fine art of integral membrane protein crystallisation
J Birch, D Axford, J Foadi, A Meyer, A Eckhardt, Y Thielmann, I Moraes
Methods 147, 150-162, 2018
782018
Toward G protein-coupled receptor structure-based drug design using X-ray lasers
A Ishchenko, B Stauch, GW Han, A Batyuk, A Shiriaeva, C Li, N Zatsepin, ...
IUCrJ 6 (6), 1106-1119, 2019
692019
X-ray structure of a CDP-alcohol phosphatidyltransferase membrane enzyme and insights into its catalytic mechanism
P Nogly, I Gushchin, A Remeeva, AM Esteves, N Borges, P Ma, ...
Nature Communications 5 (1), 4169, 2014
502014
Human mitochondrial pyruvate carrier 2 as an autonomous membrane transporter
RSK Nagampalli, JEN Quesñay, D Adamoski, Z Islam, J Birch, ...
Scientific reports 8 (1), 3510, 2018
482018
GPCR structure, function, drug discovery and crystallography: report from academia-industry international conference (UK Royal Society) Chicheley Hall, 1–2 September 2014
A Heifetz, GFX Schertler, R Seifert, CG Tate, PM Sexton, VV Gurevich, ...
Naunyn-Schmiedeberg's archives of pharmacology 388, 883-903, 2015
472015
Selection of biophysical methods for characterisation of membrane proteins
TOC Kwan, R Reis, G Siligardi, R Hussain, H Cheruvara, I Moraes
International journal of molecular sciences 20 (10), 2605, 2019
392019
Green fluorescent protein-based expression screening of membrane proteins in Escherichia coli
LE Bird, H Rada, A Verma, R Gasper, J Birch, M Jennions, J Lӧwe, ...
Journal of visualized experiments: JoVE, 52357, 2015
392015
Structures of the archaerhodopsin-3 transporter reveal that disordering of internal water networks underpins receptor sensitization
JF Bada Juarez, PJ Judge, S Adam, D Axford, J Vinals, J Birch, ...
Nature Communications 12 (1), 629, 2021
362021
Structural biology and structure–function relationships of membrane proteins
R Reis, I Moraes
Biochemical Society Transactions 47 (1), 47-61, 2019
322019
Amphipol-Trapped ExbB–ExbD Membrane Protein Complex from Escherichia coli: A Biochemical and Structural Case Study
A Sverzhinsky, S Qian, L Yang, M Allaire, I Moraes, D Ma, JW Chung, ...
The Journal of Membrane Biology 247, 1005-1018, 2014
222014
Using high-throughput in situ plate screening to evaluate the effect of dehydration on protein crystals
A Douangamath, P Aller, P Lukacik, J Sanchez-Weatherby, I Moraes, ...
Acta Crystallographica Section D: Biological Crystallography 69 (5), 920-923, 2013
212013
Membrane protein crystallography in the era of modern structural biology
TOC Kwan, D Axford, I Moraes
Biochemical Society Transactions 48 (6), 2505-2524, 2020
182020
Methods for the successful crystallization of membrane proteins
I Moraes, M Archer
Structural Proteomics: High-Throughput Methods, 211-230, 2015
152015
IUCrJ, 2, 168–176
P Nogly, D James, D Wang, TA White, N Zatsepin, A Shilova, G Nelson, ...
Web of Science CrossRef CAS PubMed IUCr Journals, 2015
142015
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