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Zhen Liang
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ADAR1p150 prevents MDA5 and PKR activation via distinct mechanisms to avert fatal autoinflammation
SB Hu, J Heraud-Farlow, T Sun, Z Liang, A Goradia, S Taylor, CR Walkley, ...
Molecular Cell 83 (21), 3869-3884. e7, 2023
352023
Quantifying nuclear wide chromatin compaction by phasor analysis of histone Förster resonance energy transfer (FRET) in frequency domain fluorescence lifetime imaging …
Z Liang, J Lou, L Scipioni, E Gratton, E Hinde
Data in Brief 30, 105401, 2020
152020
The phenotype of the most common human ADAR1p150 Zα mutation P193A in mice is partially penetrant
Z Liang, AM Chalk, S Taylor, A Goradia, JE Heraud‐Farlow, CR Walkley
EMBO reports 24 (5), e55835, 2023
132023
Generation of a new Adar1p150−/− mouse demonstrates isoform-specific roles in embryonic development and adult homeostasis
Z Liang, A Goradia, CR Walkley, JE Heraud-Farlow
RNA 29 (9), 1325-1338, 2023
82023
Phasor histone FLIM-FRET microscopy maps nuclear-wide nanoscale chromatin architecture with respect to genetically induced DNA double-strand breaks
J Lou, A Solano, Z Liang, E Hinde
Frontiers in Genetics 12, 770081, 2021
62021
The most common human ADAR1p150 Zα domain mutation P193A is well tolerated in mice and does not activate the integrated stress response pathway
Z Liang, S Taylor, A Goradia, J Heraud-Farlow, CR Walkley
bioRxiv, 2022.06. 24.497437, 2022
32022
Histone FRET reports the spatial heterogeneity in nanoscale chromatin architecture that is imparted by the epigenetic landscape at the level of single foci in an intact cell …
Z Liang, A Solano, J Lou, E Hinde
Chromosoma 133 (1), 5-14, 2024
22024
A-to-I RNA editing and hematopoiesis
Z Liang, CR Walkley, JE Heraud-Farlow
Experimental Hematology 139, 104621, 2024
2024
3192–ADAR1P150 PROTEIN, INDEPENDENT OF ITS A-TO-I RNA EDITING ACTIVITY, REGULATES PERIPHERAL T CELL HOMEOSTASIS AND HSC REPOPULATING CAPACITY
C Walkley, J Heraud-Farlow, M Stewart, M Smeets, D Izon, S Taylor, ...
Experimental Hematology 137, 104512, 2024
2024
The phasor approach to histone FLIM-FRET microscopy maps nuclear wide heterochromatin structure at the level of nucleosome proximity in a living cell
E Hinde, J Lou, Z Liang, A Solano, L Scipioni, E Gratton
Biophysical Journal 121 (3), 412a, 2022
2022
Quantifying nuclear wide chromatin compaction by phasor analysis of
Z Liang, J Lou, L Scipioni
2020
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