ADAR1p150 prevents MDA5 and PKR activation via distinct mechanisms to avert fatal autoinflammation SB Hu, J Heraud-Farlow, T Sun, Z Liang, A Goradia, S Taylor, CR Walkley, ... Molecular Cell 83 (21), 3869-3884. e7, 2023 | 35 | 2023 |
Quantifying nuclear wide chromatin compaction by phasor analysis of histone Förster resonance energy transfer (FRET) in frequency domain fluorescence lifetime imaging … Z Liang, J Lou, L Scipioni, E Gratton, E Hinde Data in Brief 30, 105401, 2020 | 15 | 2020 |
The phenotype of the most common human ADAR1p150 Zα mutation P193A in mice is partially penetrant Z Liang, AM Chalk, S Taylor, A Goradia, JE Heraud‐Farlow, CR Walkley EMBO reports 24 (5), e55835, 2023 | 13 | 2023 |
Generation of a new Adar1p150−/− mouse demonstrates isoform-specific roles in embryonic development and adult homeostasis Z Liang, A Goradia, CR Walkley, JE Heraud-Farlow RNA 29 (9), 1325-1338, 2023 | 8 | 2023 |
Phasor histone FLIM-FRET microscopy maps nuclear-wide nanoscale chromatin architecture with respect to genetically induced DNA double-strand breaks J Lou, A Solano, Z Liang, E Hinde Frontiers in Genetics 12, 770081, 2021 | 6 | 2021 |
The most common human ADAR1p150 Zα domain mutation P193A is well tolerated in mice and does not activate the integrated stress response pathway Z Liang, S Taylor, A Goradia, J Heraud-Farlow, CR Walkley bioRxiv, 2022.06. 24.497437, 2022 | 3 | 2022 |
Histone FRET reports the spatial heterogeneity in nanoscale chromatin architecture that is imparted by the epigenetic landscape at the level of single foci in an intact cell … Z Liang, A Solano, J Lou, E Hinde Chromosoma 133 (1), 5-14, 2024 | 2 | 2024 |
A-to-I RNA editing and hematopoiesis Z Liang, CR Walkley, JE Heraud-Farlow Experimental Hematology 139, 104621, 2024 | | 2024 |
3192–ADAR1P150 PROTEIN, INDEPENDENT OF ITS A-TO-I RNA EDITING ACTIVITY, REGULATES PERIPHERAL T CELL HOMEOSTASIS AND HSC REPOPULATING CAPACITY C Walkley, J Heraud-Farlow, M Stewart, M Smeets, D Izon, S Taylor, ... Experimental Hematology 137, 104512, 2024 | | 2024 |
The phasor approach to histone FLIM-FRET microscopy maps nuclear wide heterochromatin structure at the level of nucleosome proximity in a living cell E Hinde, J Lou, Z Liang, A Solano, L Scipioni, E Gratton Biophysical Journal 121 (3), 412a, 2022 | | 2022 |
Quantifying nuclear wide chromatin compaction by phasor analysis of Z Liang, J Lou, L Scipioni | | 2020 |