Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model LM Refolo, MA Pappolla, B Malester, J LaFrancois, T Bryant-Thomas, ... Neurobiology of disease 7 (4), 321-331, 2000 | 1334 | 2000 |
Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer β-amyloid peptide in rodent NH Greig, T Utsuki, DK Ingram, Y Wang, G Pepeu, C Scali, QS Yu, ... Proceedings of the National Academy of Sciences 102 (47), 17213-17218, 2005 | 810 | 2005 |
GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism Y Li, TA Perry, MS Kindy, BK Harvey, D Tweedie, HW Holloway, K Powers, ... Proceedings of the National Academy of Sciences 106 (4), 1285-1290, 2009 | 651 | 2009 |
Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration A Salehi, JD Delcroix, PV Belichenko, K Zhan, C Wu, JS Valletta, ... Neuron 51 (1), 29-42, 2006 | 608 | 2006 |
Butyrylcholinesterase: an important new target in Alzheimer's disease therapy NH Greig, DK Lahiri, K Sambamurti International psychogeriatrics 14 (S1), 77-91, 2002 | 506 | 2002 |
Glucagonlike peptide1 decreases endogenous amyloid螃 peptide (Aβ) levels and protects hippocampal neurons from death induced by Aβ and iron TA Perry, DK Lahiri, K Sambamurti, D Chen, MP Mattson, JM Egan, ... Journal of neuroscience research 72 (5), 603-612, 2003 | 417 | 2003 |
High cholesterolinduced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice L Thirumangalakudi, A Prakasam, R Zhang, H BimonteNelson, ... Journal of neurochemistry 106 (1), 475-485, 2008 | 408 | 2008 |
Amyloid-β peptide levels in brain are inversely correlated with insulysin activity levels in vivo BC Miller, EA Eckman, K Sambamurti, N Dobbs, KM Chow, CB Eckman, ... Proceedings of the National Academy of Sciences 100 (10), 6221-6226, 2003 | 374 | 2003 |
Amyloid-beta protein clearance and degradation (ABCD) pathways and their role in Alzheimer’s disease R J Baranello, K L Bharani, V Padmaraju, N Chopra, D K Lahiri, N H Greig, ... Current Alzheimer Research 12 (1), 32-46, 2015 | 373 | 2015 |
GLP-1 receptor stimulation reduces amyloid-β peptide accumulation and cytotoxicity in cellular and animal models of Alzheimer's disease Y Li, KB Duffy, MA Ottinger, B Ray, JA Bailey, HW Holloway, D Tweedie, ... Journal of Alzheimer's disease 19 (4), 1205-1219, 2010 | 360 | 2010 |
Effects of a saturated fat and high cholesterol diet on memory and hippocampal morphology in the middle-aged rat AC Granholm, HA Bimonte-Nelson, AB Moore, ME Nelson, LR Freeman, ... Journal of Alzheimer's Disease 14 (2), 133-145, 2008 | 337 | 2008 |
Reviews of evidence regarding interventions to reduce tobacco use and exposure to environmental tobacco smoke DP Hopkins, PA Briss, CJ Ricard, CG Husten, VG Carande-Kulis, ... American journal of preventive medicine 20 (2), 16-66, 2001 | 336 | 2001 |
Resolution of inflammation is altered in Alzheimer's disease X Wang, M Zhu, E Hjorth, V Cortés-Toro, H Eyjolfsdottir, C Graff, ... Alzheimer's & Dementia 11 (1), 40-50. e2, 2015 | 330 | 2015 |
Alzheimer's disease β-amyloid peptide is increased in mice deficient in endothelin-converting enzyme EA Eckman, M Watson, L Marlow, K Sambamurti, CB Eckman Journal of Biological Chemistry 278 (4), 2081-2084, 2003 | 327 | 2003 |
Exact cleavage site of Alzheimer amyloid precursor in neuronal PC-12 cells JP Anderson, FS Esch, PS Keim, K Sambamurti, I Lieberburg, NK Robakis Neuroscience letters 128 (1), 126-128, 1991 | 325 | 1991 |
Differential expression of cholesterol hydroxylases in Alzheimer's disease J Brown, C Theisler, S Silberman, D Magnuson, N Gottardi-Littell, JM Lee, ... Journal of Biological Chemistry 279 (33), 34674-34681, 2004 | 323 | 2004 |
Current drug targets for Alzheimer's disease treatment DK Lahiri, MR Farlow, NH Greig, K Sambamurti Drug development research 56 (3), 267-281, 2002 | 273 | 2002 |
Phenserine regulates translation of β-amyloid precursor protein mRNA by a putative interleukin-1 responsive element, a target for drug development KTY Shaw, T Utsuki, J Rogers, QS Yu, K Sambamurti, A Brossi, YW Ge, ... Proceedings of the National Academy of Sciences 98 (13), 7605-7610, 2001 | 267 | 2001 |
Advances in the cellular and molecular biology of the beta-amyloid protein in Alzheimer’s disease K Sambamurti, NH Greig, DK Lahiri Neuromolecular medicine 1, 1-31, 2002 | 263 | 2002 |
Human retinal pigment epithelium cells as functional models for the RPE in vivo Z Ablonczy, M Dahrouj, PH Tang, Y Liu, K Sambamurti, AD Marmorstein, ... Investigative ophthalmology & visual science 52 (12), 8614-8620, 2011 | 260 | 2011 |