Identification of a Robust ARDS Mortality-associated Neutrophil Gene Signature Using Large-scale ARDS Endotracheal Aspirate scRNA-seq O Whitley*, M Reyes*, K Kajihara, H Little-Hooy, C Chen, M De Simone, ... C108. MECHANISMS OF LUNG INFLAMMATION AND INFECTION, A6853-A6853, 2024 | | 2024 |
MultiSuSiE improves multi-ancestry fine-mapping in All of Us whole-genome sequencing data J Rossen, H Shi, BJ Strober, MJ Zhang, M Kanai, ZR McCaw, L Liang, ... medRxiv, 2024.05. 13.24307291, 2024 | | 2024 |
Pervasive correlations between causal disease effects of proximal SNPs vary with functional annotations and implicate stabilizing selection MJ Zhang, A Durvasula, C Chiang, EM Koch, BJ Strober, H Shi, ... Research Square, 2023 | 2 | 2023 |
The missing link between genetic association and regulatory function NJ Connally, S Nazeen, D Lee, H Shi, J Stamatoyannopoulos, S Chun, ... Elife 11, e74970, 2022 | 62 | 2022 |
Combining SNP-to-gene linking strategies to identify disease genes and assess disease omnigenicity S Gazal, O Weissbrod, F Hormozdiari, KK Dey, J Nasser, KA Jagadeesh, ... Nature genetics 54 (6), 827-836, 2022 | 82 | 2022 |
Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scores O Weissbrod*, M Kanai*, H Shi*, S Gazal, WJ Peyrot, AV Khera, Y Okada, ... Nature Genetics, 1-9, 2022 | 155* | 2022 |
Partitioning gene-level contributions to complex-trait heritability by allele frequency identifies disease-relevant genes KS Burch, K Hou, Y Ding, Y Wang, S Gazal, H Shi, B Pasaniuc The American Journal of Human Genetics 109 (4), 692-709, 2022 | 4 | 2022 |
Leveraging gene co-regulation to identify gene sets enriched for disease heritability KM Siewert-Rocks, SS Kim, DW Yao, H Shi, AL Price The American Journal of Human Genetics 109 (3), 393-404, 2022 | 10 | 2022 |
Mapping the human genetic architecture of COVID-19 Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ... Nature 600 (7889), 472-477, 2021 | 726 | 2021 |
A large-scale genome-wide association analysis of lung function in the Chinese population identifies novel loci and highlights shared genetic aetiology with obesity Z Zhu, J Li, J Si, B Ma, H Shi, J Lv, W Cao, Y Guo, IY Millwood, RG Walters, ... European Respiratory Journal 58 (4), 2021 | 33 | 2021 |
Technology dictates algorithms: recent developments in read alignment M Alser, J Rotman, D Deshpande, K Taraszka, H Shi, PI Baykal, HT Yang, ... Genome biology 22 (1), 249, 2021 | 109 | 2021 |
Population-specific causal disease effect sizes in functionally important regions impacted by selection H Shi, S Gazal, M Kanai, EM Koch, AP Schoech, KM Siewert, SS Kim, ... Nature communications 12 (1), 1098, 2021 | 129 | 2021 |
Obesity‐related traits and the development of rheumatoid arthritis: evidence from genetic data B Tang, H Shi, L Alfredsson, L Klareskog, L Padyukov, X Jiang Arthritis & Rheumatology 73 (2), 203-211, 2021 | 31 | 2021 |
PLEIO: a method to map and interpret pleiotropic loci with GWAS summary statistics CH Lee, H Shi, B Pasaniuc, E Eskin, B Han The American Journal of Human Genetics 108 (1), 36-48, 2021 | 35 | 2021 |
Negative short-range genomic autocorrelation of causal effects on human complex traits AP Schoech, O Weissbrod, LJ O’Connor, N Patterson, H Shi, Y Reshef, ... bioRxiv, 2020.09. 23.310748, 2020 | 5 | 2020 |
Localizing components of shared transethnic genetic architecture of complex traits from GWAS summary data H Shi*, KS Burch*, R Johnson, MK Freund, G Kichaev, N Mancuso, ... The American Journal of Human Genetics 106 (6), 805-817, 2020 | 74 | 2020 |
Shared genetic and experimental links between obesity-related traits and asthma subtypes in UK Biobank Z Zhu, Y Guo, H Shi, CL Liu, RA Panganiban, W Chung, LJ O'Connor, ... Journal of Allergy and Clinical Immunology 145 (2), 537-549, 2020 | 271 | 2020 |
Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis Z Zhu, X Zhu, CL Liu, H Shi, S Shen, Y Yang, K Hasegawa, CA Camargo, ... European Respiratory Journal 54 (6), 2019 | 124 | 2019 |
RAISS: robust and accurate imputation from summary statistics H Julienne, H Shi, B Pasaniuc, H Aschard Bioinformatics 35 (22), 4837-4839, 2019 | 17 | 2019 |
Accurate estimation of SNP-heritability from biobank-scale data irrespective of genetic architecture K Hou, KS Burch, A Majumdar, H Shi, N Mancuso, Y Wu, S Sankararaman, ... Nature Genetics 51, 1244–1251, 2019 | 101 | 2019 |