| Inhibition of reactive astrocytes with fluorocitrate retards neurovascular remodeling and recovery after focal cerebral ischemia in mice K Hayakawa, T Nakano, K Irie, S Higuchi, M Fujioka, K Orito, K Iwasaki, ... Journal of Cerebral Blood Flow & Metabolism 30 (4), 871-882, 2010 | 202 | 2010 |
| ADAMTS13 gene deletion aggravates ischemic brain damage: a possible neuroprotective role of ADAMTS13 by ameliorating postischemic hypoperfusion M Fujioka, K Hayakawa, K Mishima, A Kunizawa, K Irie, S Higuchi, ... Blood, The Journal of the American Society of Hematology 115 (8), 1650-1653, 2010 | 137 | 2010 |
| Dipeptidyl peptidase‐4 inhibitor anagliptin prevents intracranial aneurysm growth by suppressing macrophage infiltration and activation T Ikedo, M Minami, H Kataoka, K Hayashi, M Nagata, R Fujikawa, ... Journal of the American Heart Association 6 (6), e004777, 2017 | 68 | 2017 |
| Bile acid composition regulates GPR119-dependent intestinal lipid sensing and food intake regulation in mice S Higuchi, TR Ahmad, DA Argueta, PA Perez, C Zhao, GJ Schwartz, ... Gut 69 (9), 1620-1628, 2020 | 58 | 2020 |
| Therapeutic time window of cannabidiol treatment on delayed ischemic damage via high-mobility group box1-inhibiting mechanism K Hayakawa, K Irie, K Sano, T Watanabe, S Higuchi, M Enoki, T Nakano, ... Biological and Pharmaceutical Bulletin 32 (9), 1538-1544, 2009 | 52 | 2009 |
| The prostaglandin E2 receptor EP4 regulates obesity-related inflammation and insulin sensitivity M Yasui, Y Tamura, M Minami, S Higuchi, R Fujikawa, T Ikedo, M Nagata, ... PLoS One 10 (8), e0136304, 2015 | 51 | 2015 |
| Hypothalamic 2-arachidonoylglycerol regulates multistage process of high-fat diet preferences S Higuchi, K Irie, R Yamaguchi, M Katsuki, M Araki, M Ohji, K Hayakawa, ... PloS one 7 (6), e38609, 2012 | 33 | 2012 |
| Increment of hypothalamic 2-arachidonoylglycerol induces the preference for a high-fat diet via activation of cannabinoid 1 receptors S Higuchi, M Ohji, M Araki, R Furuta, M Katsuki, R Yamaguchi, Y Akitake, ... Behavioural brain research 216 (1), 477-480, 2011 | 28 | 2011 |
| The Cannabinoid 1–Receptor Silent Antagonist O-2050 Attenuates Preference for High-Fat Diet and Activated Astrocytes in Mice S Higuchi, K Irie, S Mishima, M Araki, M Ohji, A Shirakawa, Y Akitake, ... Journal of pharmacological sciences 112 (3), 369-372, 2010 | 27 | 2010 |
| EP4 receptor–associated protein in macrophages ameliorates colitis and colitis-associated tumorigenesis M Nakatsuji, M Minami, H Seno, M Yasui, H Komekado, S Higuchi, ... PLoS genetics 11 (10), e1005542, 2015 | 26 | 2015 |
| Delta (9)-tetrahydrocannabinol enhances an increase of plasma corticosterone levels induced by forced swim-stress K Sano, E Koushi, K Irie, S Higuchi, R Tsuchihashi, J Kinjo, N Egashira, ... Biological and Pharmaceutical Bulletin 32 (12), 2065-2067, 2009 | 21 | 2009 |
| Unexplained reciprocal regulation of diabetes and lipoproteins S Higuchi, MC Izquierdo, RA Haeusler Current opinion in lipidology 29 (3), 186-193, 2018 | 20 | 2018 |
| Bile acid composition regulates the manganese transporter Slc30a10 in intestine TR Ahmad, S Higuchi, E Bertaggia, A Hung, N Shanmugarajah, NC Guilz, ... Journal of Biological Chemistry 295 (35), 12545-12558, 2020 | 18 | 2020 |
| Cyp2c-deficiency depletes muricholic acids and protects against high-fat diet-induced obesity in male mice but promotes liver damage AB Oteng, S Higuchi, AS Banks, RA Haeusler Molecular metabolism 53, 101326, 2021 | 17 | 2021 |
| Deficiency in ep4 receptor–associated protein ameliorates abnormal anxiety-like behavior and brain inflammation in a mouse model of alzheimer disease R Fujikawa, S Higuchi, M Nakatsuji, M Yasui, T Ikedo, M Nagata, ... The American Journal of Pathology 187 (8), 1848-1854, 2017 | 17 | 2017 |
| EP4 Receptor− Associated Protein in Microglia Promotes Inflammation in the Brain R Fujikawa, S Higuchi, M Nakatsuji, M Yasui, T Ikedo, M Nagata, ... The American Journal of Pathology 186 (8), 1982-1988, 2016 | 13 | 2016 |
| Reducing acyl migration during purification of 2-arachidonoylglycerol from biological samples before gas chromatography mass spectrometry analysis S Higuchi, K Irie, T Nakano, Y Sakamoto, Y Akitake, M Araki, M Ohji, ... Analytical Sciences 26 (11), 1199-1202, 2010 | 12 | 2010 |
| Expression of vasohibin-1 in human carotid atherosclerotic plaque R Fukumitsu, M Minami, K Yoshida, M Nagata, M Yasui, S Higuchi, ... Journal of atherosclerosis and thrombosis 22 (9), 942-948, 2015 | 9 | 2015 |
| The physiological importance of bile acid structure and composition on glucose homeostasis S Higuchi Current Diabetes Reports 20, 1-10, 2020 | 8 | 2020 |
| EP4 Receptor–Associated Protein in Macrophages Protects against Bleomycin-Induced Pulmonary Inflammation in Mice S Higuchi, R Fujikawa, T Ikedo, K Hayashi, M Yasui, M Nagata, ... The Journal of Immunology 197 (11), 4436-4443, 2016 | 8 | 2016 |
