| A semi-synthetic organism with an expanded genetic alphabet DA Malyshev, K Dhami, T Lavergne, T Chen, N Dai, JM Foster, IR Corrêa, ... Nature 509 (7500), 385-388, 2014 | 674 | 2014 |
| Evolution of thermophilic DNA polymerases for the recognition and amplification of C2ʹ-modified DNA T Chen, N Hongdilokkul, Z Liu, R Adhikary, SS Tsuen, FE Romesberg Nature chemistry 8 (6), 556-562, 2016 | 130 | 2016 |
| Laboratory-evolved mutants of an exogenous global regulator, IrrE from Deinococcus radiodurans, enhance stress tolerances of Escherichia coli T Chen, J Wang, R Yang, J Li, M Lin, Z Lin PLoS One 6 (1), e16228, 2011 | 94 | 2011 |
| Selection of 2′-fluoro-modified aptamers with optimized properties D Thirunavukarasu, T Chen, Z Liu, N Hongdilokkul, FE Romesberg Journal of the American Chemical Society 139 (8), 2892-2895, 2017 | 84 | 2017 |
| Directed polymerase evolution T Chen, FE Romesberg FEBS letters 588 (2), 219-229, 2014 | 82 | 2014 |
| An evolved xylose transporter from Zymomonas mobilis enhances sugar transport in Escherichia coli C Ren, T Chen, J Zhang, L Liang, Z Lin Microbial cell factories 8, 1-9, 2009 | 72 | 2009 |
| The expanding world of DNA and RNA T Chen, N Hongdilokkul, Z Liu, D Thirunavukarasu, FE Romesberg Current opinion in chemical biology 34, 80-87, 2016 | 69 | 2016 |
| Evolved polymerases facilitate selection of fully 2′-OMe-modified aptamers Z Liu, T Chen, FE Romesberg Chemical Science 8 (12), 8179-8182, 2017 | 44 | 2017 |
| Adaptive mutations alter antibody structure and dynamics during affinity maturation R Adhikary, W Yu, M Oda, RC Walker, T Chen, RL Stanfield, IA Wilson, ... Biochemistry 54 (11), 2085-2093, 2015 | 39 | 2015 |
| Significant rewiring of the transcriptome and proteome of an Escherichia coli strain harboring a tailored exogenous global regulator IrrE T Chen, J Wang, L Zeng, R Li, J Li, Y Chen, Z Lin PLoS One 7 (7), e37126, 2012 | 32 | 2012 |
| Enzymatic synthesis, amplification, and application of dna with a functionalized backbone T Chen, FE Romesberg Angewandte Chemie International Edition 56 (45), 14046-14051, 2017 | 30 | 2017 |
| Selection of aptamers with large hydrophobic 2′-substituents Q Shao, T Chen, K Sheng, Z Liu, Z Zhang, FE Romesberg Journal of the American Chemical Society 142 (5), 2125-2128, 2020 | 27 | 2020 |
| Polymerase chain transcription: exponential synthesis of RNA and modified RNA T Chen, FE Romesberg Journal of the American Chemical Society 139 (29), 9949-9954, 2017 | 26 | 2017 |
| An in vivo, label-free quick assay for xylose transport in Escherichia coli T Chen, J Zhang, L Liang, R Yang, Z Lin Analytical biochemistry 390 (1), 63-67, 2009 | 18 | 2009 |
| Application of nucleic acid frameworks in the construction of nanostructures and cascade biocatalysts: recent progress and perspective G Zhu, P Song, J Wu, M Luo, Z Chen, T Chen Frontiers in Bioengineering and Biotechnology 9, 792489, 2022 | 16 | 2022 |
| Random dissection to select for protein split sites and its application in protein fragment complementation Y Chen, S Li, T Chen, H Hua, Z Lin Protein Science 18 (2), 399-409, 2009 | 16 | 2009 |
| Enzymatic synthesis of DNA with an expanded genetic alphabet using terminal deoxynucleotidyl transferase G Wang, C He, J Zou, J Liu, Y Du, T Chen ACS Synthetic Biology 11 (12), 4142-4155, 2022 | 14 | 2022 |
| From polymerase engineering to semi-synthetic life: artificial expansion of the central dogma L Sun, X Ma, B Zhang, Y Qin, J Ma, Y Du, T Chen RSC Chemical Biology 3 (10), 1173-1197, 2022 | 7 | 2022 |
| A method for the exponential synthesis of RNA: Introducing the polymerase chain transcription (PCT) reaction T Chen, FE Romesberg Biochemistry 56 (40), 5227-5228, 2017 | 7 | 2017 |
| Thermophilic Nucleic Acid Polymerases and Their Application in Xenobiology G Wang, Y Du, X Ma, F Ye, Y Qin, Y Wang, Y Xiang, R Tao, T Chen International Journal of Molecular Sciences 23 (23), 14969, 2022 | 5 | 2022 |
Denis A MalyshevFounder and COO, eGlint INC在 eglintbio.com 的电子邮件经过验证
