Mutations in the bile acid biosynthetic enzyme sterol 27-hydroxylase underlie cerebrotendinous xanthomatosis. JJ Cali, CL Hsieh, U Francke, DW Russell Journal of Biological Chemistry 266 (12), 7779-7783, 1991 | 581 | 1991 |
Characterization of human sterol 27-hydroxylase. A mitochondrial cytochrome P-450 that catalyzes multiple oxidation reaction in bile acid biosynthesis. JJ Cali, DW Russell Journal of Biological Chemistry 266 (12), 7774-7778, 1991 | 439 | 1991 |
Type VIII adenylyl cyclase. A Ca2+/calmodulin-stimulated enzyme expressed in discrete regions of rat brain. JJ Cali, JC Zwaagstra, N Mons, DM Cooper, J Krupinski Journal of Biological Chemistry 269 (16), 12190-12195, 1994 | 412 | 1994 |
Luminogenic cytochrome P450 assays JJ Cali, D Ma, M Sobol, DJ Simpson, S Frackman, TD Good, WJ Daily, ... Expert opinion on drug metabolism & toxicology 2 (4), 629-645, 2006 | 217 | 2006 |
Frameshift and splice-junction mutations in the sterol 27-hydroxylase gene cause cerebrotendinous xanthomatosis in Jews or Moroccan origin. E Leitersdorf, A Reshef, V Meiner, R Levitzki, SP Schwartz, EJ Dann, ... The Journal of clinical investigation 91 (6), 2488-2496, 1993 | 211 | 1993 |
Selective tissue distribution of G protein gamma subunits, including a new form of the gamma subunits identified by cDNA cloning. JJ Cali, EA Balcueva, I Rybalkin, JD Robishaw Journal of Biological Chemistry 267 (33), 24023-24027, 1992 | 176 | 1992 |
Type VIII adenylyl cyclase in rat beta cells: coincidence signal detector/generator for glucose and GLP-1 D Delmeire, D Flamez, SA Hinke, JJ Cali, D Pipeleers, F Schuit Diabetologia 46, 1383-1393, 2003 | 135 | 2003 |
Cloning of the human cholesterol 7α-hydroxylase gene (CYP7) and localization to chromosome 8q11–q12 JC Cohen, JJ Cali, DF Jelinek, M Mehrabian, RS Sparkes, AJ Lusis, ... Genomics 14 (1), 153-161, 1992 | 133 | 1992 |
Splice Variants of Type VIII Adenylyl Cyclase: DIFFERENCES IN GLYCOSYLATION AND REGULATION BY Ca2+/CALMODULIN (∗) JJ Cali, RS Parekh, J Krupinski Journal of Biological Chemistry 271 (2), 1089-1095, 1996 | 111 | 1996 |
Isozyme-dependent sensitivity of adenylyl cyclases to P-site-mediated inhibition by adenine nucleosides and nucleoside 3′-polyphosphates RA Johnson, L Désaubry, G Bianchi, I Shoshani, E Lyons, R Taussig, ... Journal of Biological Chemistry 272 (14), 8962-8966, 1997 | 107 | 1997 |
Bioluminescent, nonlytic, real-time cell viability assay and use in inhibitor screening SJ Duellman, W Zhou, P Meisenheimer, G Vidugiris, JJ Cali, P Gautam, ... Assay and drug development technologies 13 (8), 456-465, 2015 | 103 | 2015 |
A real-time, bioluminescent annexin V assay for the assessment of apoptosis K Kupcho, J Shultz, R Hurst, J Hartnett, W Zhou, T Machleidt, J Grailer, ... Apoptosis 24, 184-197, 2019 | 93 | 2019 |
A bioluminescent caspase-1 activity assay rapidly monitors inflammasome activation in cells M O'Brien, D Moehring, R Muñoz-Planillo, G Núñez, J Callaway, J Ting, ... Journal of immunological methods 447, 1-13, 2017 | 90 | 2017 |
Bioluminescent assays for ADMET JJ Cali, A Niles, MP Valley, MA O'Brien, TL Riss, J Shultz Expert opinion on drug metabolism & toxicology 4 (1), 103-120, 2008 | 73 | 2008 |
N-Alkylated 6′-aminoluciferins are bioluminescent substrates for Ultra-Glo and QuantiLum luciferase: new potential scaffolds for bioluminescent assays CC Woodroofe, JW Shultz, MG Wood, J Osterman, JJ Cali, WJ Daily, ... Biochemistry 47 (39), 10383-10393, 2008 | 68 | 2008 |
A bioluminescent assay for monoamine oxidase activity MP Valley, W Zhou, EM Hawkins, J Shultz, JJ Cali, T Worzella, L Bernad, ... Analytical biochemistry 359 (2), 238-246, 2006 | 65 | 2006 |
Dimerization of mammalian adenylate cyclases: functional, biochemical and fluorescence resonance energy transfer (FRET) studies C Gu, JJ Cali, DMF Cooper European journal of biochemistry 269 (2), 413-421, 2002 | 62 | 2002 |
Validation of a HTS-amenable assay to detect drug-induced mitochondrial toxicity in the absence and presence of cell death R Swiss, A Niles, JJ Cali, S Nadanaciva, Y Will Toxicology In Vitro 27 (6), 1789-1797, 2013 | 55 | 2013 |
Luminogenic and fluorogenic compounds and methods to detect molecules or conditions JJ Cali, W Daily, E Hawkins, D Klaubert, J Liu, P Meisenheimer, M Scurria, ... US Patent 7,951,550, 2011 | 53 | 2011 |
Luciferase-based assays E Hawkins, JJ Cali, SKS Ho, MA O'brien, R Somberg, RF Bulleit, KV Wood US Patent 7,741,067, 2010 | 53 | 2010 |