A thermostable Cas12b from Brevibacillus leverages one-pot discrimination of SARS-CoV-2 variants of concern LT Nguyen, NC Macaluso, BLM Pizzano, MN Cash, J Spacek, J Karasek, ... EBioMedicine 77, 2022 | 48 | 2022 |
Clinical validation of engineered CRISPR/Cas12a for rapid SARS-CoV-2 detection LT Nguyen, SR Rananaware, BLM Pizzano, BT Stone, PK Jain Communications Medicine 2 (1), 7, 2022 | 31 | 2022 |
Engineering highly thermostable Cas12b via de novo structural analyses for one-pot detection of nucleic acids LT Nguyen, SR Rananaware, LG Yang, NC Macaluso, JE Ocana-Ortiz, ... Cell Reports Medicine 4 (5), 2023 | 16 | 2023 |
CRISPR-ENHANCE: An enhanced nucleic acid detection platform using Cas12a LT Nguyen, J Gurijala, SR Rananaware, BLM Pizzano, BT Stone, PK Jain Methods 203, 116-124, 2022 | 16 | 2022 |
Engineered CRISPR/Cas12a Enables Rapid SARS-CoV-2 Detection LT Nguyen, SR Rananaware, BLM Pizzano, BT Stone, PK Jain MedRxiv, 2020.12. 23.20248725, 2020 | 8 | 2020 |
Harnessing noncanonical crRNAs to improve functionality of Cas12a orthologs LT Nguyen, NC Macaluso, NR Rakestraw, DR Carman, BLM Pizzano, ... Cell reports 43 (2), 2024 | 4 | 2024 |
Efficient Genome Editing with Chimeric Oligonucleotide-Directed Editing LT Nguyen, NR Rakestraw, BLM Pizzano, CB Young, Y Huang, ... bioRxiv, 2024.07. 09.602710, 2024 | | 2024 |
PAM-free diagnostics with diverse type V CRISPR-Cas systems SR Rananaware, KS Meister, GM Shoemaker, EK Vesco, LSW Sandoval, ... medRxiv, 2024.05. 02.24306194, 2024 | | 2024 |
Multiplexing of Cas Orthologs for Disease Detection BLM Pizzano, LG Yang, SR Rananaware, A Fang, SG Antal, ZR Fang, ... 2023 AIChE Annual Meeting, 2023 | | 2023 |
Characterizing Cas12i Proteins As Novel Enzymes for Diagnostics and Gene Editing C Orosco, S Rananaware, M Chang, Z Fang, L Yang, N Rakestraw, ... 2023 AIChE Annual Meeting, 2023 | | 2023 |
PAM-Independent Detection of Nucleic Acid Targets with CRISPR-Cas12a S Rananaware, K Meister, G Shoemaker, EK Vesco, LSW Sandoval, ... 2023 AIChE Annual Meeting, 2023 | | 2023 |
PAM-Independent Detection of Nucleic Acid Targets with CRISPR-Cas12a K Meister, S Rananaware, LSW Sandoval, EK Vesco, G Shoemaker, ... 2022 AIChE Annual Meeting, 2022 | | 2022 |
Engineering Highly Thermostable Cas12b Via De Novo Structural Analyses for One-Pot Detection of Nucleic Acids J Ocana-Ortiz, L Nguyen, SR Rananaware, L Yang, NC Macaluso, ... 2022 AIChE Annual Meeting, 2022 | | 2022 |
Expanding the CRISPR/Cas Toolbox for Nucleic Acid Detection L Nguyen, SR Rananaware, NC Macaluso, BLM Pizzano, L Yang, ... 5th International Conference on CRISPR Technologies, 2022 | | 2022 |
A Thermostable Cas12b fromBrevibacillusLeverages One-pot Detection of SARS-CoV-2 Variants of Concern LT Nguyen, NC Macaluso, BL Pizzano, MN Cash, J Spacek, J Karasek, ... | | 2021 |
A Thermostable Cas12b from Brevibacillus Leverages One-pot Detection of SARS-CoV-2 Variants of Concern LT Nguyen, NC Macaluso, BLM Pizzano, MN Cash, J Spacek, J Karasek, ... medRxiv, 2021.10. 15.21265066, 2021 | | 2021 |