| EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy JG Paez, PA Janne, JC Lee, S Tracy, H Greulich, S Gabriel, P Herman, ... Science 304 (5676), 1497-1500, 2004 | 11999 | 2004 |
| EGFR Mutation and Resistance of Non–Small-Cell Lung Cancer to Gefitinib S Kobayashi, TJ Boggon, T Dayaram, PA Jänne, O Kocher, M Meyerson, ... New England Journal of Medicine 352 (8), 786-792, 2005 | 4795 | 2005 |
| Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis RL Levine, M Wadleigh, J Cools, BL Ebert, G Wernig, BJP Huntly, ... Cancer cell 7 (4), 387-397, 2005 | 3840 | 2005 |
| Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma M Krauthammer, Y Kong, BH Ha, P Evans, A Bacchiocchi, JP McCusker, ... Nature genetics 44 (9), 1006-1014, 2012 | 1332 | 2012 |
| Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer Z Zhang, JC Lee, L Lin, V Olivas, V Au, T LaFramboise, M Abdel-Rahman, ... Nature genetics 44 (8), 852-860, 2012 | 1288 | 2012 |
| Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity CH Yun, TJ Boggon, Y Li, MS Woo, H Greulich, M Meyerson, MJ Eck Cancer cell 11 (3), 217-227, 2007 | 1219 | 2007 |
| Structure and regulation of Src family kinases TJ Boggon, MJ Eck Oncogene 23 (48), 7918-7927, 2004 | 906 | 2004 |
| C-cadherin ectodomain structure and implications for cell adhesion mechanisms TJ Boggon, J Murray, S Chappuis-Flament, E Wong, BM Gumbiner, ... Science 296 (5571), 1308-1313, 2002 | 847 | 2002 |
| Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth T Hitosugi, S Kang, MG Vander Heiden, TW Chung, S Elf, K Lythgoe, ... Science signaling 2 (97), ra73-ra73, 2009 | 838 | 2009 |
| BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations DB Costa, B Halmos, A Kumar, ST Schumer, MS Huberman, TJ Boggon, ... PLoS medicine 4 (10), e315, 2007 | 580 | 2007 |
| Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation N Romberg, K Al Moussawi, C Nelson-Williams, AL Stiegler, E Loring, ... Nature genetics 46 (10), 1135-1139, 2014 | 504 | 2014 |
| G-protein signaling through tubby proteins S Santagata, TJ Boggon, CL Baird, CA Gomez, J Zhao, WS Shan, ... Science 292 (5524), 2041-2050, 2001 | 462 | 2001 |
| The structure and clinical relevance of the EGF receptor in human cancer A Kumar, ET Petri, B Halmos, TJ Boggon Journal of clinical oncology: official journal of the American Society of …, 2008 | 458 | 2008 |
| Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth T Hitosugi, L Zhou, S Elf, J Fan, HB Kang, JH Seo, C Shan, Q Dai, ... Cancer cell 22 (5), 585-600, 2012 | 434 | 2012 |
| Genomic landscape of cutaneous T cell lymphoma J Choi, G Goh, T Walradt, BS Hong, CG Bunick, K Chen, RD Bjornson, ... Nature genetics 47 (9), 1011-1019, 2015 | 428 | 2015 |
| Activating alleles of JAK3 in acute megakaryoblastic leukemia DK Walters, T Mercher, TL Gu, T O'Hare, JW Tyner, M Loriaux, VL Goss, ... Cancer cell 10 (1), 65-75, 2006 | 363 | 2006 |
| Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism T Hitosugi, J Fan, TW Chung, K Lythgoe, X Wang, J Xie, Q Ge, TL Gu, ... Molecular cell 44 (6), 864-877, 2011 | 342 | 2011 |
| Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth L Jin, D Li, GN Alesi, J Fan, HB Kang, Z Lu, TJ Boggon, P Jin, H Yi, ... Cancer cell 27 (2), 257-270, 2015 | 329 | 2015 |
| Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma S Zhao, M Choi, JD Overton, S Bellone, DM Roque, E Cocco, F Guzzo, ... Proceedings of the National Academy of Sciences 110 (8), 2916-2921, 2013 | 319 | 2013 |
| Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex J Fan, C Shan, HB Kang, S Elf, J Xie, M Tucker, TL Gu, M Aguiar, ... Molecular cell 53 (4), 534-548, 2014 | 290 | 2014 |
