Rationally designed small compounds inhibit pilus biogenesis in uropathogenic bacteria JS Pinkner, H Remaut, F Buelens, E Miller, V Åberg, N Pemberton, ... Proceedings of the National Academy of Sciences 103 (47), 17897-17902, 2006 | 371 | 2006 |
Structural and mechanistic insights into the bacterial amyloid secretion channel CsgG P Goyal, PV Krasteva, N Van Gerven, F Gubellini, I Van den Broeck, ... Nature 516 (7530), 250-253, 2014 | 330 | 2014 |
Secreted amyloid-β precursor protein functions as a GABABR1a ligand to modulate synaptic transmission HC Rice, D De Malmazet, A Schreurs, S Frere, I Van Molle, AN Volkov, ... Science 363 (6423), eaao4827, 2019 | 283 | 2019 |
Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist CN Spaulding, RD Klein, S Ruer, AL Kau, HL Schreiber, ZT Cusumano, ... Nature 546 (7659), 528-532, 2017 | 280 | 2017 |
Fiber assembly by the chaperone–usher pathway FG Sauer, H Remaut, SJ Hultgren, G Waksman Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1694 (1-3), 259-267, 2004 | 269 | 2004 |
Fiber formation across the bacterial outer membrane by the chaperone/usher pathway H Remaut, C Tang, NS Henderson, JS Pinkner, T Wang, SJ Hultgren, ... Cell 133 (4), 640-652, 2008 | 255 | 2008 |
Helicobacter pylori adhesin HopQ engages in a virulence-enhancing interaction with human CEACAMs A Javaheri, T Kruse, K Moonens, R Mejías-Luque, A Debraekeleer, ... Nature microbiology 2 (1), 1-13, 2016 | 254 | 2016 |
Protein–protein interaction through β-strand addition H Remaut, G Waksman Trends in biochemical sciences 31 (8), 436-444, 2006 | 231 | 2006 |
Crystal structure of the FimD usher bound to its cognate FimC–FimH substrate G Phan, H Remaut, T Wang, WJ Allen, KF Pirker, A Lebedev, ... Nature 474 (7349), 49-53, 2011 | 214 | 2011 |
Architectures and biogenesis of non‐flagellar protein appendages in Gram‐negative bacteria R Fronzes, H Remaut, G Waksman The EMBO journal 27 (17), 2271-2280, 2008 | 211 | 2008 |
Donor-strand exchange in chaperone-assisted pilus assembly proceeds through a concerted β strand displacement mechanism H Remaut, RJ Rose, TJ Hannan, SJ Hultgren, SE Radford, AE Ashcroft, ... Molecular cell 22 (6), 831-842, 2006 | 202 | 2006 |
Bacterial amyloid formation: structural insights into curli biogensis N Van Gerven, RD Klein, SJ Hultgren, H Remaut Trends in microbiology 23 (11), 693-706, 2015 | 185 | 2015 |
The role of functional amyloids in bacterial virulence N Van Gerven, SE Van der Verren, DM Reiter, H Remaut Journal of molecular biology 430 (20), 3657-3684, 2018 | 157 | 2018 |
SbsB structure and lattice reconstruction unveil Ca2+ triggered S-layer assembly E Baranova, R Fronzes, A Garcia-Pino, N Van Gerven, D Papapostolou, ... Nature 487 (7405), 119-122, 2012 | 149 | 2012 |
Structural insights into Helicobacter pylori oncoprotein CagA interaction with β1 integrin B Kaplan-Türköz, LF Jiménez-Soto, C Dian, C Ertl, H Remaut, A Louche, ... Proceedings of the National Academy of Sciences 109 (36), 14640-14645, 2012 | 142 | 2012 |
Helicobacter pylori adapts to chronic infection and gastric disease via pH-responsive BabA-mediated adherence JA Bugaytsova, O Björnham, YA Chernov, P Gideonsson, S Henriksson, ... Cell host & microbe 21 (3), 376-389, 2017 | 141 | 2017 |
Small heat-shock protein HSPB1 mutants stabilize microtubules in Charcot-Marie-Tooth neuropathy L Almeida-Souza, B Asselbergh, C d'Ydewalle, K Moonens, S Goethals, ... Journal of neuroscience 31 (43), 15320-15328, 2011 | 118 | 2011 |
Design and synthesis of C-2 substituted thiazolo and dihydrothiazolo ring-fused 2-pyridones: pilicides with increased antivirulence activity E Chorell, JS Pinkner, G Phan, S Edvinsson, F Buelens, H Remaut, ... Journal of medicinal chemistry 53 (15), 5690-5695, 2010 | 113 | 2010 |
Structural insights into polymorphic ABO glycan binding by Helicobacter pylori K Moonens, P Gideonsson, S Subedi, J Bugaytsova, E Romaõ, M Mendez, ... Cell host & microbe 19 (1), 55-66, 2016 | 112 | 2016 |
Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM T Uchański, S Masiulis, B Fischer, V Kalichuk, U López-Sánchez, ... Nature methods 18 (1), 60-68, 2021 | 110 | 2021 |