Induction of Chronic Myelogenous Leukemia in Mice by the P210bcr/abl Gene of the Philadelphia Chromosome GQ Daley, RA Van Etten, D Baltimore Science 247 (4944), 824-830, 1990 | 2874 | 1990 |
Sequence and gene organization of mouse mitochondrial DNA MJ Bibb, RA Van Etten, CT Wright, MW Walberg, DA Clayton Cell 26 (2), 167-180, 1981 | 2139 | 1981 |
Tyrosine kinases as targets for cancer therapy DS Krause, RA Van Etten New England Journal of Medicine 353 (2), 172-187, 2005 | 1800 | 2005 |
Cardiotoxicity of the cancer therapeutic agent imatinib mesylate R Kerkelä, L Grazette, R Yacobi, C Iliescu, R Patten, C Beahm, B Walters, ... Nature medicine 12 (8), 908-916, 2006 | 1406 | 2006 |
Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition T Force, DS Krause, RA Van Etten Nature Reviews Cancer 7 (5), 332-344, 2007 | 929 | 2007 |
Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression CA Neumann, DS Krause, CV Carman, S Das, DP Dubey, JL Abraham, ... Nature 424 (6948), 561-565, 2003 | 927 | 2003 |
The price of drugs for chronic myeloid leukemia (CML) is a reflection of the unsustainable prices of cancer drugs: from the perspective of a large group of CML experts Experts in Chronic Myeloid Leukemia Blood, The Journal of the American Society of Hematology 121 (22), 4439-4442, 2013 | 692 | 2013 |
Targeting autophagy potentiates tyrosine kinase inhibitor–induced cell death in Philadelphia chromosome–positive cells, including primary CML stem cells C Bellodi, MR Lidonnici, A Hamilton, GV Helgason, AR Soliera, ... The Journal of clinical investigation 119 (5), 1109-1123, 2009 | 688 | 2009 |
P210 and P190BCR/ABL induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members RL Ilaria, RA Van Etten Journal of Biological Chemistry 271 (49), 31704-31710, 1996 | 665 | 1996 |
The P190, P210, and P230 Forms of the BCR/ABL Oncogene Induce a Similar Chronic Myeloid Leukemia–like Syndrome in Mice but Have Different Lymphoid … S Li, RL Ilaria Jr, RP Million, GQ Daley, RA Van Etten The Journal of experimental medicine 189 (9), 1399-1412, 1999 | 632 | 1999 |
The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization RA Van Etten, P Jackson, D Baltimore Cell 58 (4), 669-678, 1989 | 573 | 1989 |
Reversibility of acute B-cell leukaemia induced by BCR–ABL1 CS Huettner, P Zhang, RA Van Etten, DG Tenen Nature genetics 24 (1), 57-60, 2000 | 525 | 2000 |
Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia Y Hu, Y Liu, S Pelletier, E Buchdunger, M Warmuth, D Fabbro, M Hallek, ... Nature genetics 36 (5), 453-461, 2004 | 506 | 2004 |
Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth LR Zukerberg, GN Patrick, M Nikolic, S Humbert, CL Wu, LM Lanier, ... Neuron 26 (3), 633-646, 2000 | 490 | 2000 |
Requirement for CD44 in homing and engraftment of BCR-ABL–expressing leukemic stem cells DS Krause, K Lazarides, UH von Andrian, RA Van Etten Nature medicine 12 (10), 1175-1180, 2006 | 487 | 2006 |
Critical role for Gab2 in transformation by BCR/ABL M Sattler, MG Mohi, YB Pride, LR Quinnan, NA Malouf, K Podar, ... Cancer cell 1 (5), 479-492, 2002 | 478 | 2002 |
Cycling, stressed-out and nervous: cellular functions of c-Abl RA Van Etten Trends in cell biology 9 (5), 179-186, 1999 | 474 | 1999 |
The COOH terminus of the c-Abl tyrosine kinase contains distinct F-and G-actin binding domains with bundling activity RA Van Etten, PK Jackson, D Baltimore, MC Sanders, PT Matsudaira, ... The Journal of cell biology 124 (3), 325-340, 1994 | 400 | 1994 |
Point mutations in the abl SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo BJ Mayer, PK Jackson, RA Van Etten, D Baltimore Molecular and cellular biology, 1992 | 378 | 1992 |
c-Abl has high intrinsic tyrosine kinase activity that is stimulated by mutation of the Src homology 3 domain and by autophosphorylation at two distinct regulatory tyrosines BB Brasher, RA Van Etten Journal of Biological Chemistry 275 (45), 35631-35637, 2000 | 359 | 2000 |