Impact of diabetes on long-term prognosis in patients with unstable angina and non–Q-wave myocardial infarction: results of the OASIS (Organization to Assess Strategies for … K Malmberg, S Yusuf, HC Gerstein, J Brown, F Zhao, D Hunt, L Piegas, ... Circulation 102 (9), 1014-1019, 2000 | 1195 | 2000 |
Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family Y Wang, S Huang, VP Sah, J Ross Jr, JH Brown, J Han, KR Chien Journal of Biological Chemistry 273 (4), 2161-2168, 1998 | 1111 | 1998 |
Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. A paracrine mechanism for myocardial cell … HE Shubeita, PM McDonough, AN Harris, KU Knowlton, CC Glembotski, ... Journal of Biological Chemistry 265 (33), 20555-20562, 1990 | 794 | 1990 |
Muscarinic receptor agonists and antagonists JH Brown, P Taylor Goodman & Gilman's the pharmacological basis of therapeutics 11, 183-200, 2006 | 781 | 2006 |
The δC Isoform of CaMKII Is Activated in Cardiac Hypertrophy and Induces Dilated Cardiomyopathy and Heart Failure T Zhang, LS Maier, ND Dalton, S Miyamoto, J Ross Jr, DM Bers, ... Circulation research 92 (8), 912-919, 2003 | 756 | 2003 |
Enhanced Gαq signaling: a common pathway mediates cardiac hypertrophy and apoptotic heart failure JW Adams, Y Sakata, MG Davis, VP Sah, Y Wang, SB Liggett, KR Chien, ... Proceedings of the National Academy of Sciences 95 (17), 10140-10145, 1998 | 710 | 1998 |
Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels S Wagner, N Dybkova, ECL Rasenack, C Jacobshagen, L Fabritz, ... The Journal of clinical investigation 116 (12), 3127-3138, 2006 | 619 | 2006 |
Transgenic CaMKIIδC Overexpression Uniquely Alters Cardiac Myocyte Ca2+ Handling: Reduced SR Ca2+ Load and Activated SR Ca2+ Release LS Maier, T Zhang, L Chen, J DeSantiago, JH Brown, DM Bers Circulation research 92 (8), 904-911, 2003 | 602 | 2003 |
Local InsP3-dependent perinuclear Ca2+ signaling in cardiac myocyte excitation-transcription coupling X Wu, T Zhang, J Bossuyt, X Li, TA McKinsey, JR Dedman, EN Olson, ... The Journal of clinical investigation 116 (3), 675-682, 2006 | 593 | 2006 |
Linkage of β1-adrenergic stimulation to apoptotic heart cell death through protein kinase A–independent activation of Ca2+/calmodulin kinase II WZ Zhu, SQ Wang, K Chakir, D Yang, T Zhang, JH Brown, E Devic, ... The Journal of clinical investigation 111 (5), 617-625, 2003 | 575 | 2003 |
CaMKII in myocardial hypertrophy and heart failure ME Anderson, JH Brown, DM Bers Journal of molecular and cellular cardiology 51 (4), 468-473, 2011 | 567 | 2011 |
The pharmacological basis of therapeutics LL Brunton, B Chabner, BC Knollmann McGraw-Hill, 2011 | 554* | 2011 |
Cardiotrophin 1 (CT-1) inhibition of cardiac myocyte apoptosis via a mitogen-activated protein kinase-dependent pathway: divergence from downstream CT-1 signals for myocardial … Z Sheng, K Knowlton, J Chen, M Hoshijima, JH Brown, KR Chien Journal of biological chemistry 272 (9), 5783-5791, 1997 | 523 | 1997 |
The role of Rho in G protein-coupled receptor signal transduction VP Sah, TM Seasholtz, SA Sagi, JH Brown Annual review of pharmacology and toxicology 40 (1), 459-489, 2000 | 489 | 2000 |
Requirement for Ca2+/calmodulin–dependent kinase II in the transition from pressure overload–induced cardiac hypertrophy to heart failure in mice H Ling, T Zhang, L Pereira, CK Means, H Cheng, Y Gu, ND Dalton, ... The Journal of clinical investigation 119 (5), 1230-1240, 2009 | 473 | 2009 |
MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice D Zhang, R Contu, MVG Latronico, J Zhang, R Rizzi, D Catalucci, ... The Journal of clinical investigation 120 (8), 2805-2816, 2010 | 458 | 2010 |
The Rac and Rho hall of fame: a decade of hypertrophic signaling hits JH Brown, DP Del Re, MA Sussman Circulation research 98 (6), 730-742, 2006 | 457 | 2006 |
Cyclophilin D controls mitochondrial pore–dependent Ca2+ exchange, metabolic flexibility, and propensity for heart failure in mice JW Elrod, R Wong, S Mishra, RJ Vagnozzi, B Sakthievel, ... The Journal of clinical investigation 120 (10), 3680-3687, 2010 | 442 | 2010 |
Cardiac hypertrophy induced by mitogen-activated protein kinase kinase 7, a specific activator for c-Jun NH2-terminal kinase in ventricular muscle cells Y Wang, B Su, VP Sah, JH Brown, J Han, KR Chien Journal of Biological Chemistry 273 (10), 5423-5426, 1998 | 438 | 1998 |
Akt mediates mitochondrial protection in cardiomyocytes through phosphorylation of mitochondrial hexokinase-II S Miyamoto, AN Murphy, JH Brown Cell Death & Differentiation 15 (3), 521-529, 2008 | 422 | 2008 |