| 2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity PL Sulkowski, CD Corso, ND Robinson, SE Scanlon, KR Purshouse, ... Science translational medicine 9 (375), eaal2463, 2017 | 524 | 2017 |
| Oncometabolites suppress DNA repair by disrupting local chromatin signalling PL Sulkowski, S Oeck, J Dow, NG Economos, L Mirfakhraie, Y Liu, ... Nature 582 (7813), 586-591, 2020 | 241 | 2020 |
| Krebs-cycle-deficient hereditary cancer syndromes are defined by defects in homologous-recombination DNA repair PL Sulkowski, RK Sundaram, S Oeck, CD Corso, Y Liu, S Noorbakhsh, ... Nature genetics 50 (8), 1086-1092, 2018 | 190 | 2018 |
| In vivo correction of anaemia in β-thalassemic mice by γPNA-mediated gene editing with nanoparticle delivery R Bahal, N Ali McNeer, E Quijano, Y Liu, P Sulkowski, A Turchick, YC Lu, ... Nature communications 7 (1), 13304, 2016 | 161 | 2016 |
| Mitochondrial DNA stress signalling protects the nuclear genome Z Wu, S Oeck, AP West, KC Mangalhara, AG Sainz, LE Newman, ... Nature metabolism 1 (12), 1209-1218, 2019 | 105 | 2019 |
| Mcp1 promotes macrophage-dependent cyst expansion in autosomal dominant polycystic kidney disease MF Cassini, VR Kakade, E Kurtz, P Sulkowski, P Glazer, R Torres, ... Journal of the American Society of Nephrology 29 (10), 2471-2481, 2018 | 99 | 2018 |
| Nickel induces transcriptional down-regulation of DNA repair pathways in tumorigenic and non-tumorigenic lung cells SE Scanlon, CD Scanlon, DC Hegan, PL Sulkowski, PM Glazer Carcinogenesis 38 (6), 627-637, 2017 | 48 | 2017 |
| miR-155 overexpression promotes genomic instability by reducing high-fidelity polymerase delta expression and activating error-prone DSB repair JR Czochor, P Sulkowski, PM Glazer Molecular Cancer Research 14 (4), 363-373, 2016 | 48 | 2016 |
| PTEN regulates nonhomologous end joining by epigenetic induction of NHEJ1/XLF PL Sulkowski, SE Scanlon, S Oeck, PM Glazer Molecular Cancer Research 16 (8), 1241-1254, 2018 | 25 | 2018 |
| Suppression of homology-dependent DNA double-strand break repair induces PARP inhibitor sensitivity in VHL-deficient human renal cell carcinoma SE Scanlon, DC Hegan, PL Sulkowski, PM Glazer Oncotarget 9 (4), 4647, 2018 | 25 | 2018 |
| LINE-1 activation in the cerebellum drives ataxia T Takahashi, M Stoiljkovic, E Song, XB Gao, Y Yasumoto, E Kudo, ... Neuron 110 (20), 3278-3287. e8, 2022 | 18 | 2022 |
| Abstract LB-029: Negative transcriptional and epigenetic regulation of DNA repair pathways by the heavy metals nickel and arsenic SE Scanlon, CD Scanlon, DC Hegan, P Sulkowski, PM Glazer Cancer Research 76 (14_Supplement), LB-029-LB-029, 2016 | 2 | 2016 |
| Response to: Elevated L1 expression in ataxia telangiectasia likely explained by an RNA-seq batch effect T Takahashi, M Stoiljkovic, E Song, XB Gao, Y Yasumoto, E Kudo, ... Neuron 111 (5), 612-613, 2023 | 1 | 2023 |
| Nanoparticle-Mediated Correction of the Sickle Cell Mutation E Quijano, R Bahal, Y Liu, A Gupta, S Oyaghire, AS Ricciardi, HK Mandl, ... MOLECULAR THERAPY 27 (4), 278-278, 2019 | 1 | 2019 |
| Compositions and methods for targeting cancers R Bindra, P Glazer, P Sulkowski, B Shuch US Patent 11,311,538, 2022 | | 2022 |
| Oncometabolites suppress homologous recombination DNA repair by inhibition of chromatin remodeling at the DNA double-strand break PS Sulkowski, S Oeck, J Li, B Shuch, MC King, RS Bindra, PM Glazer CANCER RESEARCH 79 (13), 2019 | | 2019 |
| Abstract SY21-02: Oncometabolites suppress homologous recombination DNA repair by inhibition of chromatin remodeling at the DNA double-strand break PS Sulkowski, S Oeck, J Li, B Shuch, MC King, RS Bindra, PM Glazer Cancer Research 79 (13_Supplement), SY21-02-SY21-02, 2019 | | 2019 |
| Compositions and methods for targeting and treating homologous recombination-deficient tumors R Bindra, P Glazer, N Robinson, P Sulkowski, C Corso US Patent App. 16/306,215, 2019 | | 2019 |
| Production of 2-Hydroxyglutarate by IDH Mutant Malignancies Induces a BRCAness State That Can be Exploited By PARP Inhibitors and Radiation CD Corso, RS Bindra, PM Glazer, PL Sulkowski, ND Robinson, ... International Journal of Radiation Oncology, Biology, Physics 99 (2), E68, 2017 | | 2017 |
| Abstract LB-290: Oncometabolites induce a BRCAness state that can be exploited by PARP inhibitors P Sulkowski, C Corso, N Robinson, S Scanlon, K Purshouse, H Bai, Y Liu, ... Cancer Research 77 (13_Supplement), LB-290-LB-290, 2017 | | 2017 |
