Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA AS Tan, JW Baty, LF Dong, A Bezawork-Geleta, B Endaya, J Goodwin, ... Cell metabolism 21 (1), 81-94, 2015 | 722 | 2015 |
Endothelial KLF2 links local arterial shear stress levels to the expression of vascular tone-regulating genes RJ Dekker, JV Van Thienen, J Rohlena, SC De Jager, YW Elderkamp, ... The American journal of pathology 167 (2), 609-618, 2005 | 449 | 2005 |
Mitochondrial complex II: at the crossroads A Bezawork-Geleta, J Rohlena, L Dong, K Pacak, J Neuzil Trends in biochemical sciences 42 (4), 312-325, 2017 | 271 | 2017 |
Classification of mitocans, anti-cancer drugs acting on mitochondria J Neuzil, LF Dong, J Rohlena, J Truksa, SJ Ralph Mitochondrion 13 (3), 199-208, 2013 | 268 | 2013 |
Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells LF Dong, J Kovarova, M Bajzikova, A Bezawork-Geleta, D Svec, ... elife 6, e22187, 2017 | 261 | 2017 |
Key transcriptional regulators of the vasoprotective effects of shear stress RA Boon, AJG Horrevoets Hämostaseologie 29 (01), 39-43, 2009 | 236 | 2009 |
Mitochondrial targeting of vitamin E succinate enhances its pro-apoptotic and anti-cancer activity via mitochondrial complex II LF Dong, VJA Jameson, D Tilly, J Cerny, E Mahdavian, ... Journal of Biological Chemistry 286 (5), 3717-3728, 2011 | 234 | 2011 |
Reactivation of dihydroorotate dehydrogenase-driven pyrimidine biosynthesis restores tumor growth of respiration-deficient cancer cells M Bajzikova, J Kovarova, AR Coelho, S Boukalova, S Oh, K Rohlenova, ... Cell metabolism 29 (2), 399-416. e10, 2019 | 217 | 2019 |
Prolonged shear stress and KLF2 suppress constitutive proinflammatory transcription through inhibition of ATF2 JO Fledderus, JV Van Thienen, RA Boon, RJ Dekker, J Rohlena, ... Blood 109 (10), 4249-4257, 2007 | 197 | 2007 |
Shear stress sustains atheroprotective endothelial KLF2 expression more potently than statins through mRNA stabilization JV van Thienen, JO Fledderus, RJ Dekker, J Rohlena, GA van IJzendoorn, ... Cardiovascular research 72 (2), 231-240, 2006 | 183 | 2006 |
Suppression of tumor growth in vivo by the mitocan α-tocopheryl succinate requires respiratory complex II LF Dong, R Freeman, J Liu, R Zobalova, A Marin-Hernandez, M Stantic, ... Clinical Cancer Research 15 (5), 1593-1600, 2009 | 148 | 2009 |
Platelets facilitate the wound-healing capability of mesenchymal stem cells by mitochondrial transfer and metabolic reprogramming J Levoux, A Prola, P Lafuste, M Gervais, N Chevallier, Z Koumaiha, K Kefi, ... Cell metabolism 33 (2), 283-299. e9, 2021 | 142 | 2021 |
Mitochondrial complex II, a novel target for anti-cancer agents K Kluckova, A Bezawork-Geleta, J Rohlena, L Dong, J Neuzil Biochimica et Biophysica Acta (BBA)-Bioenergetics 1827 (5), 552-564, 2013 | 138 | 2013 |
Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: a new paradigm for effective cancer therapy LF Dong, VJA Jameson, D Tilly, L Prochazka, J Rohlena, K Valis, J Truksa, ... Free Radical Biology and Medicine 50 (11), 1546-1555, 2011 | 124 | 2011 |
Mitochondrial complex II and reactive oxygen species in disease and therapy K Hadrava Vanova, M Kraus, J Neuzil, J Rohlena Redox Report 25 (1), 26-32, 2020 | 118 | 2020 |
Hippo/Mst1 stimulates transcription of the proapoptotic mediator NOXA in a FoxO1-dependent manner K Valis, L Prochazka, E Boura, J Chladova, T Obsil, J Rohlena, J Truksa, ... Cancer research 71 (3), 946-954, 2011 | 113 | 2011 |
Selective Disruption of Respiratory Supercomplexes as a New Strategy to Suppress Her2high Breast Cancer K Rohlenova, K Sachaphibulkij, J Stursa, A Bezawork-Geleta, J Blecha, ... Antioxidants & redox signaling 26 (2), 84-103, 2017 | 112 | 2017 |
Anticancer drugs targeting the mitochondrial electron transport chain J Rohlena, LF Dong, SJ Ralph, J Neuzil Antioxidants & redox signaling 15 (12), 2951-2974, 2011 | 110 | 2011 |
Dihydroorotate dehydrogenase in oxidative phosphorylation and cancer S Boukalova, S Hubackova, M Milosevic, Z Ezrova, J Neuzil, J Rohlena Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1866 (6), 165759, 2020 | 94 | 2020 |
Selective elimination of senescent cells by mitochondrial targeting is regulated by ANT2 S Hubackova, E Davidova, K Rohlenova, J Stursa, L Werner, L Andera, ... Cell Death & Differentiation 26 (2), 276-290, 2019 | 91 | 2019 |