| Serum biomarkers for connective tissue and basement membrane remodeling are associated with vertebral endplate bone marrow lesions as seen on MRI (Modic changes) S Dudli, A Ballatori, AC Bay-Jensen, ZL McCormick, CW O’Neill, ... International journal of molecular sciences 21 (11), 3791, 2020 | 20 | 2020 |
| Extrinsic macrophages protect while tendon progenitors degrade: Insights from a tissue engineered model of tendon compartmental crosstalk T Stauber, M Wolleb, A Duss, PK Jaeger, I Heggli, AA Hussien, U Blache, ... Advanced Healthcare Materials 10 (20), 2100741, 2021 | 16 | 2021 |
| CD90-positive stromal cells associate with inflammatory and fibrotic changes in modic changes S Dudli, A Karol, L Giudici, I Heggli, CJ Laux, JM Spirig, F Wanivenhaus, ... Osteoarthritis and Cartilage Open 4 (3), 100287, 2022 | 13 | 2022 |
| Low back pain patients with Modic type 1 changes exhibit distinct bacterial and non-bacterial subtypes I Heggli, T Mengis, CJ Laux, L Opitz, N Herger, D Menghini, ... Osteoarthritis and Cartilage Open 6 (1), 100434, 2024 | 9 | 2024 |
| Pro-fibrotic phenotype of bone marrow stromal cells in Modic type 1 changes I Heggli, S Epprecht, A Juengel, R Schuepbach, NA Farshad-Amacker, ... European Cells and Materials (ECM) 41, 648-667, 2021 | 9 | 2021 |
| Modic type 2 changes are fibroinflammatory changes with complement system involvement adjacent to degenerated vertebral endplates I Heggli, CJ Laux, T Mengis, A Karol, F Cornaz, N Herger, B Aradi‐Vegh, ... JOR spine 6 (1), e1237, 2023 | 8 | 2023 |
| Role of C‐reactive protein in the bone marrow of Modic type 1 changes S Dudli, I Heggli, CJ Laux, JM Spirig, F Wanivenhaus, M Betz, C Germann, ... Journal of Orthopaedic Research® 41 (5), 1115-1122, 2023 | 7 | 2023 |
| OP0083 infectious and autoinflammatory modic type 1 changes have different pathomechanisms I Heggli, R Schüpbach, N Herger, TA Schweizer, A Jüngel, ... Annals of the Rheumatic Diseases 80 (Suppl 1), 45-45, 2021 | 6 | 2021 |
| Acute and chronic effects of a light-activated FGF receptor in keratinocytes in vitro and in mice T Rauschendorfer, S Gurri, I Heggli, L Maddaluno, M Meyer, ... Life Science Alliance 4 (11), 2021 | 5 | 2021 |
| The role of the complement system in disc degeneration and Modic changes I Heggli, GQ Teixeira, JC Iatridis, C Neidlinger‐Wilke, S Dudli JOR spine 7 (1), e1312, 2024 | 4 | 2024 |
| Intervertebral disc cell chondroptosis elicits neutrophil response in Staphylococcus aureus spondylodiscitis TA Schweizer, F Andreoni, C Acevedo, TC Scheier, I Heggli, EM Maggio, ... Frontiers in Immunology 13, 908211, 2022 | 4 | 2022 |
| Impacts of priming on distinct immunosuppressive mechanisms of mesenchymal stromal cells under translationally relevant conditions N Herger, I Heggli, T Mengis, J Devan, L Arpesella, F Brunner, O Distler, ... Stem Cell Research & Therapy 15 (1), 65, 2024 | 2 | 2024 |
| AB1398 STROMAL CELLS IN MODIC TYPE 1 CHANGE BONE MARROW PROMOTE NEURITE OUTGROWTH T Mengis, I Heggli, N Herger, B Aradi-Vegh, F Brunner, M Farshad, ... Annals of the Rheumatic Diseases 82 (Suppl 1), 1928-1928, 2023 | 1 | 2023 |
| POS0416 distinct degeneration mechanisms in intervertebral discs adjacent to Modic changes T Mengis, I Heggli, N Herger, B Aradi-Vegh, B Roschitzki, J Grossmann, ... Annals of the Rheumatic Diseases 82 (Suppl 1), 463-464, 2023 | 1 | 2023 |
| POS0417 ACTIVATED NEUTROPHILS DEGRADE CARTILAGE ENDPLATES I Heggli, M Habib, J Scheer, N Herger, T Mengis, C Laux, F Wanivenhaus, ... Annals of the Rheumatic Diseases 82 (Suppl 1), 464-465, 2023 | 1 | 2023 |
| Fgf2 overrides key pro-fibrotic features of bone marrow stromal cells isolated from modic type 1 change patients I Heggli, U Blache, N Herger, T Mengis, PK Jaeger, R Schuepbach, ... European Cells & Materials 44, 101-114, 2022 | 1 | 2022 |
| Proteomic analysis of serum in a population‐based cohort did not reveal a biomarker for Modic changes F Schulze, J Määttä, S Grad, I Heggli, F Brunner, M Farshad, O Distler, ... JOR spine 7 (3), e1337, 2024 | | 2024 |
| The Expression of Toll-like Receptors in Cartilage Endplate Cells: A Role of Toll-like Receptor 2 in Pro-Inflammatory and Pro-Catabolic Gene Expression T Mengis, L Bernhard, A Nüesch, I Heggli, N Herger, J Devan, R Marcus, ... Cells 13 (17), 1402, 2024 | | 2024 |
| POS0343 HIGHER ABUNDANCE OF HTRA1 GENERATED FRAGMENTS IN THE DEGRADOME OF MODIC TYPE 1 DISCS T Mengis, B Roschitzki, I Heggli, N Herger, M Farshad, O Distler, S Dudli Annals of the Rheumatic Diseases 83 (Suppl 1), 353-354, 2024 | | 2024 |
| POS0526 ACCUMULATION OF STRESS-INDUCED MOLECULES RECOGNIZING T CELLS IN MODIC TYPE 1 CHANGES J Devan, S Dudli, N Herger, T Mengis, I Heggli, MPV Valdes, M Farshad, ... Annals of the Rheumatic Diseases 83 (Suppl 1), 1106-1107, 2024 | | 2024 |
