关注
Nuno M. F. S. A. Cerqueira
Nuno M. F. S. A. Cerqueira
Requimte, Faculdade de Ciências, Universidade do Porto
在 fc.up.pt 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Cholesterol biosynthesis: a mechanistic overview
NM Cerqueira, EF Oliveira, DS Gesto, D Santos-Martins, C Moreira, ...
Biochemistry 55 (39), 5483-5506, 2016
3522016
Understanding ribonucleotide reductase inactivation by gemcitabine
NM Cerqueira, PA Fernandes, MJ Ramos
Chemistry–A European Journal 13 (30), 8507-8515, 2007
2132007
Application of quantum mechanics/molecular mechanics methods in the study of enzymatic reaction mechanisms
SF Sousa, AJM Ribeiro, RPP Neves, NF Brás, NM Cerqueira, ...
Wiley Interdisciplinary Reviews: Computational Molecular Science 7 (2), e1281, 2017
1742017
Receptor-based virtual screening protocol for drug discovery
NM Cerqueira, D Gesto, EF Oliveira, D Santos-Martins, NF Brás, ...
Archives of biochemistry and biophysics 582, 56-67, 2015
1492015
Overview of ribonucleotide reductase inhibitors: an appealing target in anti-tumour therapy
NM Cerqueira, S Pereira, PA Fernandes, MJ Ramos
Current medicinal chemistry 12 (11), 1283-1294, 2005
1362005
Synthesis of N-aryl-5-amino-4-cyanopyrazole derivatives as potent xanthine oxidase inhibitors
S Gupta, LM Rodrigues, AP Esteves, AMF Oliveira-Campos, ...
European journal of medicinal chemistry 43 (4), 771-780, 2008
1292008
Mechanism of formation of the internal aldimine in pyridoxal 5′-phosphate-dependent enzymes
EF Oliveira, NM Cerqueira, PA Fernandes, MJ Ramos
Journal of the American Chemical Society 133 (39), 15496-15505, 2011
1192011
Periplasmic nitrate reductase revisited: a sulfur atom completes the sixth coordination of the catalytic molybdenum
S Najmudin, PJ González, J Trincao, C Coelho, A Mukhopadhyay, ...
JBIC Journal of Biological Inorganic Chemistry 13, 737-753, 2008
1192008
Gemcitabine: a critical nucleoside for cancer therapy
D S Gesto, N MFSA Cerqueira, P A Fernandes, M J Ramos
Current medicinal chemistry 19 (7), 1076-1087, 2012
1172012
Ribonucleotide reductase: a critical enzyme for cancer chemotherapy and antiviral agents
NM Cerqueira, PA Fernandes, MJ Ramos
Recent patents on anti-cancer drug discovery 2 (1), 11-29, 2007
1142007
Virtual screening in drug design and development
S F Sousa, N MFSA Cerqueira, P A Fernandes, M Joao Ramos
Combinatorial chemistry & high throughput screening 13 (5), 442-453, 2010
1122010
The mechanism of formate oxidation by metal-dependent formate dehydrogenases
CS Mota, MG Rivas, CD Brondino, I Moura, JJG Moura, PJ González, ...
JBIC Journal of Biological Inorganic Chemistry 16, 1255-1268, 2011
1002011
Glycosidase inhibitors: a patent review (2008–2013)
NF Brás, NM Cerqueira, MJ Ramos, PA Fernandes
Expert Opinion on Therapeutic Patents 24 (8), 857-874, 2014
942014
PLP-dependent enzymes as important biocatalysts for the pharmaceutical, chemical and food industries: a structural and mechanistic perspective
JF Rocha, AF Pina, SF Sousa, NM Cerqueira
Catalysis Science & Technology 9 (18), 4864-4876, 2019
822019
Unravelling the olfactory sense: from the gene to odor perception
CS Silva Teixeira, NM Cerqueira, AC Silva Ferreira
Chemical Senses 41 (2), 105-121, 2016
762016
Unraveling the Enigmatic Mechanism of l-Asparaginase II with QM/QM Calculations
DS Gesto, NM Cerqueira, PA Fernandes, MJ Ramos
Journal of the American Chemical Society 135 (19), 7146-7158, 2013
712013
The sulfur shift: an activation mechanism for periplasmic nitrate reductase and formate dehydrogenase
NM Cerqueira, PA Fernandes, PJ Gonzalez, JJG Moura, MJ Ramos
Inorganic Chemistry 52 (19), 10766-10772, 2013
702013
Aryl-and heteroaryl-thiosemicarbazone derivatives and their metal complexes: a pharmacological template
N Moorthy, NM Cerqueira, MJ Ramos, PA Fernandes
Recent Pat. Anti-Cancer Drug Discovery 8 (2), 168-182, 2013
642013
The effect of the sixth sulfur ligand in the catalytic mechanism of periplasmic nitrate reductase
N Cerqueira, PJ Gonzalez, CD Brondino, MJ Romão, CC Romao, I Moura, ...
Journal of computational chemistry 30 (15), 2466-2484, 2009
642009
Dehydration of ribonucleotides catalyzed by ribonucleotide reductase: The role of the enzyme
NM Cerqueira, PA Fernandes, LA Eriksson, MJ Ramos
Biophysical journal 90 (6), 2109-2119, 2006
642006
系统目前无法执行此操作,请稍后再试。
文章 1–20