The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse E Mezzaroma, S Toldo, D Farkas, IM Seropian, BW Van Tassell, ... Proceedings of the National Academy of Sciences 108 (49), 19725-19730, 2011 | 647 | 2011 |
Phosphodiesterase-5 inhibition with sildenafil attenuates cardiomyocyte apoptosis and left ventricular dysfunction in a chronic model of doxorubicin cardiotoxicity PW Fisher, F Salloum, A Das, H Hyder, RC Kukreja Circulation 111 (13), 1601-1610, 2005 | 435 | 2005 |
Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU … A Abbate, MC Kontos, JD Grizzard, GGL Biondi-Zoccai, BW Van Tassell, ... The American journal of cardiology 105 (10), 1371-1377. e1, 2010 | 434 | 2010 |
Anakinra, a recombinant human interleukin-1 receptor antagonist, inhibits apoptosis in experimental acute myocardial infarction A Abbate, FN Salloum, E Vecile, A Das, NN Hoke, S Straino, ... Circulation 117 (20), 2670-2683, 2008 | 427 | 2008 |
Sildenafil (Viagra) induces powerful cardioprotective effect via opening of mitochondrial KATP channels in rabbits R Ockaili, F Salloum, J Hawkins, RC Kukreja American Journal of Physiology-Heart and Circulatory Physiology 283 (3 …, 2002 | 384 | 2002 |
Adrenergic receptor blockade reverses right heart remodeling and dysfunction in pulmonary hypertensive rats HJ Bogaard, R Natarajan, S Mizuno, A Abbate, PJ Chang, VQ Chau, ... American journal of respiratory and critical care medicine 182 (5), 652-660, 2010 | 319 | 2010 |
Sildenafil induces delayed preconditioning through inducible nitric oxide synthase–dependent pathway in mouse heart F Salloum, C Yin, L Xi, RC Kukreja Circulation Research 92 (6), 595-597, 2003 | 315 | 2003 |
HIF-1 activation attenuates postischemic myocardial injury: role for heme oxygenase-1 in modulating microvascular chemokine generation R Ockaili, R Natarajan, F Salloum, BJ Fisher, D Jones, AA Fowler III, ... American Journal of Physiology-Heart and Circulatory Physiology 289 (2 …, 2005 | 296 | 2005 |
A novel role of microRNA in late preconditioning: upregulation of endothelial nitric oxide synthase and heat shock protein 70 C Yin, FN Salloum, RC Kukreja Circulation Research 104 (5), 572-575, 2009 | 269 | 2009 |
Pharmacological preconditioning with sildenafil: basic mechanisms and clinical implications RC Kukreja, F Salloum, A Das, R Ockaili, C Yin, YA Bremer, PW Fisher, ... Vascular pharmacology 42 (5-6), 219-232, 2005 | 258 | 2005 |
Mitochondrial-targeted Signal transducer and activator of transcription 3 (STAT3) protects against ischemia-induced changes in the electron transport chain and the generation … K Szczepanek, Q Chen, M Derecka, FN Salloum, Q Zhang, M Szelag, ... Journal of Biological Chemistry 286 (34), 29610-29620, 2011 | 248 | 2011 |
PDE5 inhibitors as therapeutics for heart disease, diabetes and cancer A Das, D Durrant, FN Salloum, L Xi, RC Kukreja Pharmacology & therapeutics 147, 12-21, 2015 | 244 | 2015 |
Sildenafil (Viagra) attenuates ischemic cardiomyopathy and improves left ventricular function in mice FN Salloum, A Abbate, A Das, JE Houser, CA Mudrick, IZ Qureshi, ... American Journal of Physiology-Heart and Circulatory Physiology 294 (3 …, 2008 | 241 | 2008 |
Hypoxia inducible factor-1 activation by prolyl 4-hydroxylase-2 gene silencing attenuates myocardial ischemia reperfusion injury R Natarajan, FN Salloum, BJ Fisher, RC Kukreja, AA Fowler III Circulation research 98 (1), 133-140, 2006 | 236 | 2006 |
Rapamycin confers preconditioning-like protection against ischemia–reperfusion injury in isolated mouse heart and cardiomyocytes SA Khan, F Salloum, A Das, L Xi, GW Vetrovec, RC Kukreja Journal of molecular and cellular cardiology 41 (2), 256-264, 2006 | 223 | 2006 |
Inhibition of the NLRP3 inflammasome limits the inflammatory injury following myocardial ischemia–reperfusion in the mouse S Toldo, C Marchetti, AG Mauro, J Chojnacki, E Mezzaroma, S Carbone, ... International Journal of Cardiology 209, 215-220, 2016 | 203 | 2016 |
The NHLBI-Sponsored Consortium for preclinicAl assESsment of cARdioprotective Therapies (CAESAR) A New Paradigm for Rigorous, Accurate, and Reproducible Evaluation of Putative … SP Jones, XL Tang, Y Guo, C Steenbergen, DJ Lefer, RC Kukreja, ... Circulation research 116 (4), 572-586, 2015 | 201 | 2015 |
Cardioprotection with phosphodiesterase-5 inhibition—a novel preconditioning strategy RC Kukreja, R Ockaili, F Salloum, C Yin, J Hawkins, A Das, L Xi Journal of molecular and cellular cardiology 36 (2), 165-173, 2004 | 197 | 2004 |
Phosphodiesterase-5 inhibitor, tadalafil, protects against myocardial ischemia/reperfusion through protein-kinase G–dependent generation of hydrogen sulfide FN Salloum, VQ Chau, NN Hoke, A Abbate, A Varma, RA Ockaili, S Toldo, ... Circulation 120 (11_suppl_1), S31-S36, 2009 | 194 | 2009 |
MicroRNAs: new players in cardiac injury and protection RC Kukreja, C Yin, FN Salloum Molecular pharmacology 80 (4), 558-564, 2011 | 191 | 2011 |