Mitochondrial targeting of vitamin E succinate enhances its pro-apoptotic and anti-cancer activity via mitochondrial complex II LF Dong, VJA Jameson, D Tilly, J Cerny, E Mahdavian, ... Journal of Biological Chemistry 286 (5), 3717-3728, 2011 | 234 | 2011 |
Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: a new paradigm for effective cancer therapy LF Dong, VJA Jameson, D Tilly, L Prochazka, J Rohlena, K Valis, J Truksa, ... Free Radical Biology and Medicine 50 (11), 1546-1555, 2011 | 124 | 2011 |
Selective Disruption of Respiratory Supercomplexes as a New Strategy to Suppress Her2high Breast Cancer K Rohlenova, K Sachaphibulkij, J Stursa, A Bezawork-Geleta, J Blecha, ... Antioxidants & redox signaling 26 (2), 84-103, 2017 | 112 | 2017 |
Metformin regulates global DNA methylation via mitochondrial one-carbon metabolism E Cuyàs, S Fernández-Arroyo, S Verdura, RÁF García, J Stursa, L Werner, ... Oncogene 37 (7), 963-970, 2018 | 104 | 2018 |
Selective elimination of senescent cells by mitochondrial targeting is regulated by ANT2 S Hubackova, E Davidova, K Rohlenova, J Stursa, L Werner, L Andera, ... Cell Death & Differentiation 26 (2), 276-290, 2019 | 91 | 2019 |
Mitochondrially targeted vitamin E succinate efficiently kills breast tumour-initiating cells in a complex II-dependent manner B Yan, M Stantic, R Zobalova, A Bezawork-Geleta, M Stapelberg, J Stursa, ... BMC cancer 15, 1-12, 2015 | 79 | 2015 |
Metformin directly targets the H3K27me3 demethylase KDM6A/UTX E Cuyas, S Verdura, L Llorach‐Pares, S Fernández‐Arroyo, ... Aging cell 17 (4), e12772, 2018 | 71 | 2018 |
Mitochondrial targeting of metformin enhances its activity against pancreatic cancer S Boukalova, J Stursa, L Werner, Z Ezrova, J Cerny, A Bezawork-Geleta, ... Molecular cancer therapeutics 15 (12), 2875-2886, 2016 | 69 | 2016 |
Mitochondrially targeted α-tocopheryl succinate is antiangiogenic: potential benefit against tumor angiogenesis but caution against wound healing J Rohlena, LF Dong, K Kluckova, R Zobalova, J Goodwin, D Tilly, J Stursa, ... Antioxidants & redox signaling 15 (12), 2923-2935, 2011 | 69 | 2011 |
Targeting mitochondrial iron metabolism suppresses tumor growth and metastasis by inducing mitochondrial dysfunction and mitophagy C Sandoval-Acuna, N Torrealba, V Tomkova, SB Jadhav, K Blazkova, ... Cancer Research 81 (9), 2289-2303, 2021 | 67 | 2021 |
Mitochondrially targeted vitamin E succinate modulates expression of mitochondrial DNA transcripts and mitochondrial biogenesis J Truksa, LF Dong, J Rohlena, J Stursa, M Vondrusova, J Goodwin, ... Antioxidants & redox signaling 22 (11), 883-900, 2015 | 50 | 2015 |
Mitochondrial targeting overcomes ABCA1-dependent resistance of lung carcinoma to α-tocopheryl succinate L Prochazka, S Koudelka, LF Dong, J Stursa, J Goodwin, J Neca, J Slavik, ... Apoptosis 18, 286-299, 2013 | 47 | 2013 |
Mitochondrial targeting of α-tocopheryl succinate enhances its anti-mesothelioma efficacy J Kovarova, M Bajzikova, M Vondrusova, J Stursa, J Goodwin, M Nguyen, ... Redox Report 19 (1), 16-25, 2014 | 42 | 2014 |
Indoleamine-2, 3-dioxygenase elevated in tumor-initiating cells is suppressed by mitocans M Stapelberg, R Zobalova, MN Nguyen, T Walker, M Stantic, J Goodwin, ... Free Radical Biology and Medicine 67, 41-50, 2014 | 37 | 2014 |
Microwave-Assisted Alkylation of [CB11H12]− and Related Anions M Valášek, J Štursa, R Pohl, J Michl Inorganic chemistry 49 (22), 10247-10254, 2010 | 33 | 2010 |
Characterisation of mesothelioma-initiating cells and their susceptibility to anti-cancer agents EA Pasdar, M Smits, M Stapelberg, M Bajzikova, M Stantic, J Goodwin, ... PLoS One 10 (5), e0119549, 2015 | 30 | 2015 |
Measured and Calculated Oxidation Potentials of 1-X-12-Y-CB11Me10– Anions A Wahab, B Stepp, C Douvris, M Valasek, J Stursa, J Klı́ma, MC Piqueras, ... Inorganic Chemistry 51 (9), 5128-5137, 2012 | 27 | 2012 |
SMAD4 loss limits the vulnerability of pancreatic cancer cells to complex I inhibition via promotion of mitophagy Z Ezrova, Z Nahacka, J Stursa, L Werner, E Vlcak, P Kralova Viziova, ... Oncogene 40 (14), 2539-2552, 2021 | 25 | 2021 |
Lithium Salts of [1,12-Dialkyl-CB11Me10]− Anions M Valášek, J Štursa, R Pohl, J Michl Inorganic chemistry 49 (22), 10255-10263, 2010 | 24 | 2010 |
Structural re-arrangement and peroxidase activation of cytochrome c by anionic analogues of vitamin E, tocopherol succinate and tocopherol phosphate N Yanamala, AA Kapralov, M Djukic, J Peterson, G Mao, ... Journal of Biological Chemistry 289 (47), 32488-32498, 2014 | 21 | 2014 |