The structure of the biofilm-controlling response regulator BfmR from Acinetobacter baumannii reveals details of its DNA-binding mechanism GL Draughn, ME Milton, EA Feldmann, BG Bobay, BM Roth, AL Olson, ... Journal of molecular biology 430 (6), 806-821, 2018 | 54 | 2018 |
Re-sensitizing multidrug resistant bacteria to antibiotics by targeting bacterial response regulators: characterization and comparison of interactions between 2-aminoimidazoles … ME Milton, BM Minrovic, DL Harris, B Kang, D Jung, CP Lewis, ... Frontiers in Molecular Biosciences 5, 15, 2018 | 33 | 2018 |
The solution structures and interaction of SinR and SinI: elucidating the mechanism of action of the master regulator switch for biofilm formation in Bacillus subtilis ME Milton, GL Draughn, BG Bobay, SD Stowe, AL Olson, EA Feldmann, ... Journal of molecular biology 432 (2), 343-357, 2020 | 31 | 2020 |
Replication and maintenance of the Plasmodium falciparum apicoplast genome ME Milton, SW Nelson Molecular and biochemical parasitology 208 (2), 56-64, 2016 | 28 | 2016 |
Structure of the Francisella response regulator QseB receiver domain, and characterization of QseB inhibition by antibiofilm 2‐aminoimidazole‐based compounds ME Milton, CL Allen, EA Feldmann, BG Bobay, DK Jung, MD Stephens, ... Molecular microbiology 106 (2), 223-235, 2017 | 26 | 2017 |
Acinetobacter baumannii regulates its stress responses via the BfmRS two-component regulatory system S Palethorpe, JM Farrow III, G Wells, ME Milton, LA Actis, J Cavanagh, ... Journal of bacteriology 204 (2), e00494-21, 2022 | 25 | 2022 |
A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum ME Miller, EE Parrott, R Singh, SW Nelson Journal of biomolecular screening 19 (6), 966-972, 2014 | 17 | 2014 |
Francisella novicida Two-Component System Response Regulator BfpR Modulates iglC Gene Expression, Antimicrobial Peptide Resistance, and Biofilm Production SN Dean, ME Milton, J Cavanagh, ML Van Hoek Frontiers in Cellular and Infection Microbiology 10, 82, 2020 | 15 | 2020 |
Crystal structure of the apicoplast DNA polymerase from plasmodium falciparum: the first look at a plastidic A-Family DNA polymerase ME Milton, JY Choe, RB Honzatko, SW Nelson Journal of molecular biology 428 (20), 3920-3934, 2016 | 12 | 2016 |
Structure of the Acinetobacter baumannii PmrA receiver domain and insights into clinical mutants affecting DNA binding and promoting colistin resistance S Palethorpe, ME Milton, EC Pesci, J Cavanagh Journal of Biochemistry 170 (6), 787-800, 2021 | 7 | 2021 |
The biofilm regulatory network from Bacillus subtilis: A structure-function analysis ME Milton, J Cavanagh Journal of Molecular Biology 435 (3), 167923, 2023 | 4 | 2023 |
Crystallization and preliminary X-ray analysis of the Plasmodium falciparum apicoplast DNA polymerase ME Milton, J Choe, RB Honzatko, SW Nelson Acta Crystallographica Section F: Structural Biology Communications 71 (3 …, 2015 | 4 | 2015 |
Computational and cellular exploration of the protein-protein interaction between Vibrio fischeri STAS domain protein SypA and serine kinase SypE ME Milton, KL Visick Communicative & Integrative Biology 16 (1), 2203626, 2023 | 1 | 2023 |
2-Aminoimidazole Analogs Target PhoP Altering DNA Binding Activity and Affect Outer Membrane Stability in Gram-Negative Bacteria TN Zeczycki, ME Milton, D Jung, RJ Thompson, FE Jaimes, AD Hondros, ... Biochemistry 61 (24), 2948-2960, 2022 | 1 | 2022 |
Inhibition and Dispersion of Biofilms: Targeting Bacterial Response Regulators to Resensitize Multidrug Resistant Bacteria to Antibiotics ME Milton, GL Draughn, EA Feldmann, RJ Thompson, D Jung, B Kang, ... The FASEB Journal 31 (1_supplement), 939.15-939.15, 2017 | 1 | 2017 |
Insights into DNA-binding motifs and mechanisms of Francisella tularensis novicida two-component system response regulator proteins QseB, KdpE, and BfpR KE Gaddy, EM Bensch, J Cavanagh, ME Milton Biochemical and Biophysical Research Communications 722, 150150, 2024 | | 2024 |
Filling in the gaps for the master regulator of biofilm formation in Bacillus subtilis: A structural and biochemical look at SinR and SinI ME Milton, GL Draughn, BG Bobay, SD Stowe, AL Olson, EA Feldmann, ... The FASEB Journal 33 (S1), 631.30-631.30, 2019 | | 2019 |
Resensitizing Multidrug Resistant Bacteria to Antibiotics by Targeting Bacterial Response Regulators ME Milton, BM Minrovic, DL Harris, GL Draughn, B Kang, D Jung, ... The FASEB Journal 32 (1_supplement), 810.5-810.5, 2018 | | 2018 |
Exploration of the Atypical Regions of the Plasmodium falciparum Apicoplast DNA Polymerase and Their Potential Role in Antimalarial Drug Discovery ME Milton, RB Honzatko, SW Nelson The FASEB Journal 30 (1_supplement), 578.2-578.2, 2016 | | 2016 |
Structure and function of the Plasmodium falciparum apicoplast DNA polymerase: the first look at an" atypical" A-family polymerase and its potential in antimalarial drug discovery ME Milton Iowa State Univeristy, 2016 | | 2016 |