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Dhruv Chauhan
Dhruv Chauhan
Post-doctoral scientist, Janssen Pharmaceutica
在 its.jnj.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Human monocytes engage an alternative inflammasome pathway
MM Gaidt, TS Ebert, D Chauhan, T Schmidt, JL Schmid-Burgk, F Rapino, ...
Immunity 44 (4), 833-846, 2016
7862016
The DNA inflammasome in human myeloid cells is initiated by a STING-cell death program upstream of NLRP3
MM Gaidt, TS Ebert, D Chauhan, K Ramshorn, F Pinci, S Zuber, F O’Duill, ...
Cell 171 (5), 1110-1124. e18, 2017
5172017
A genome-wide CRISPR (clustered regularly interspaced short palindromic repeats) screen identifies NEK7 as an essential component of NLRP3 inflammasome activation
JL Schmid-Burgk, D Chauhan, T Schmidt, TS Ebert, J Reinhardt, E Endl, ...
Journal of Biological Chemistry 291 (1), 103-109, 2016
4372016
Cytosolic RNA: DNA hybrids activate the cGAS–STING axis
AK Mankan, T Schmidt, D Chauhan, M Goldeck, K Höning, M Gaidt, ...
The EMBO journal 33 (24), 2937-2946, 2014
3232014
Therapeutic modulation of inflammasome pathways
D Chauhan, L Vande Walle, M Lamkanfi
Immunological reviews 297 (1), 123-138, 2020
1602020
BAX/BAK-induced apoptosis results in caspase-8-dependent IL-1β maturation in macrophages
D Chauhan, E Bartok, MM Gaidt, FJ Bock, J Herrmann, JM Seeger, P Broz, ...
Cell reports 25 (9), 2354-2368. e5, 2018
932018
Post-injury immunosuppression and secondary infections are caused by an AIM2 inflammasome-driven signaling cascade
S Roth, J Cao, V Singh, S Tiedt, G Hundeshagen, T Li, JD Boehme, ...
Immunity 54 (4), 648-659. e8, 2021
802021
IKKβ primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network
NA Schmacke, F O’Duill, MM Gaidt, I Szymanska, JM Kamper, ...
Immunity 55 (12), 2271-2284. e7, 2022
552022
GSDMD drives canonical inflammasome‐induced neutrophil pyroptosis and is dispensable for NETosis
D Chauhan, D Demon, L Vande Walle, O Paerewijck, A Zecchin, ...
EMBO reports 23 (10), e54277, 2022
462022
Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3
M Von Gamm, A Schaub, AN Jones, C Wolf, G Behrens, J Lichti, K Essig, ...
The Journal of experimental medicine 216 (7), 1700, 2019
352019
A genome-wide CRISPR screen identifies NEK7 as an essential component of NLRP3 inflammasome activation
JL Schmid-Burgk, D Chauhan, T Schmidt, TS Ebert, J Reinhardt, E Endl, ...
J. Biol. Chem 291 (1), 103-9, 2015
292015
Activation of the NLRP3 Inflammasome by Hyaboron, a New Asymmetric Boron-Containing Macrodiolide from the Myxobacterium Hyalangium minutum
F Surup, D Chauhan, J Niggemann, E Bartok, J Herrmann, M Keck, ...
ACS chemical biology 13 (10), 2981-2988, 2018
222018
Priming enables a NEK7-independent route of NLRP3 activation
NA Schmacke, MM Gaidt, I Szymanska, F O’Duill, CA Stafford, D Chauhan, ...
bioRxiv, 799320, 2019
212019
In silico genome analysis reveals the evolution and potential impact of SARS-CoV-2 Omicron structural changes on host immune evasion and antiviral therapeutics
D Chauhan, N Chakravarty, AV Jeyachandran, A Jayakarunakaran, ...
Viruses 14 (11), 2461, 2022
72022
Review on dimensionality reduction techniques
D Chauhan, R Mathews
Proceeding of the International Conference on Computer Networks, Big Data …, 2020
72020
Structural basis for the oligomerization-facilitated NLRP3 activation
X Yu, RE Matico, R Miller, D Chauhan, B Van Schoubroeck, K Grauwen, ...
Nature Communications 15 (1), 1164, 2024
42024
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