Human monocytes engage an alternative inflammasome pathway MM Gaidt, TS Ebert, D Chauhan, T Schmidt, JL Schmid-Burgk, F Rapino, ... Immunity 44 (4), 833-846, 2016 | 786 | 2016 |
The DNA inflammasome in human myeloid cells is initiated by a STING-cell death program upstream of NLRP3 MM Gaidt, TS Ebert, D Chauhan, K Ramshorn, F Pinci, S Zuber, F O’Duill, ... Cell 171 (5), 1110-1124. e18, 2017 | 517 | 2017 |
A genome-wide CRISPR (clustered regularly interspaced short palindromic repeats) screen identifies NEK7 as an essential component of NLRP3 inflammasome activation JL Schmid-Burgk, D Chauhan, T Schmidt, TS Ebert, J Reinhardt, E Endl, ... Journal of Biological Chemistry 291 (1), 103-109, 2016 | 437 | 2016 |
Cytosolic RNA: DNA hybrids activate the cGAS–STING axis AK Mankan, T Schmidt, D Chauhan, M Goldeck, K Höning, M Gaidt, ... The EMBO journal 33 (24), 2937-2946, 2014 | 323 | 2014 |
Therapeutic modulation of inflammasome pathways D Chauhan, L Vande Walle, M Lamkanfi Immunological reviews 297 (1), 123-138, 2020 | 160 | 2020 |
BAX/BAK-induced apoptosis results in caspase-8-dependent IL-1β maturation in macrophages D Chauhan, E Bartok, MM Gaidt, FJ Bock, J Herrmann, JM Seeger, P Broz, ... Cell reports 25 (9), 2354-2368. e5, 2018 | 93 | 2018 |
Post-injury immunosuppression and secondary infections are caused by an AIM2 inflammasome-driven signaling cascade S Roth, J Cao, V Singh, S Tiedt, G Hundeshagen, T Li, JD Boehme, ... Immunity 54 (4), 648-659. e8, 2021 | 80 | 2021 |
IKKβ primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network NA Schmacke, F O’Duill, MM Gaidt, I Szymanska, JM Kamper, ... Immunity 55 (12), 2271-2284. e7, 2022 | 55 | 2022 |
GSDMD drives canonical inflammasome‐induced neutrophil pyroptosis and is dispensable for NETosis D Chauhan, D Demon, L Vande Walle, O Paerewijck, A Zecchin, ... EMBO reports 23 (10), e54277, 2022 | 46 | 2022 |
Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3 M Von Gamm, A Schaub, AN Jones, C Wolf, G Behrens, J Lichti, K Essig, ... The Journal of experimental medicine 216 (7), 1700, 2019 | 35 | 2019 |
A genome-wide CRISPR screen identifies NEK7 as an essential component of NLRP3 inflammasome activation JL Schmid-Burgk, D Chauhan, T Schmidt, TS Ebert, J Reinhardt, E Endl, ... J. Biol. Chem 291 (1), 103-9, 2015 | 29 | 2015 |
Activation of the NLRP3 Inflammasome by Hyaboron, a New Asymmetric Boron-Containing Macrodiolide from the Myxobacterium Hyalangium minutum F Surup, D Chauhan, J Niggemann, E Bartok, J Herrmann, M Keck, ... ACS chemical biology 13 (10), 2981-2988, 2018 | 22 | 2018 |
Priming enables a NEK7-independent route of NLRP3 activation NA Schmacke, MM Gaidt, I Szymanska, F O’Duill, CA Stafford, D Chauhan, ... bioRxiv, 799320, 2019 | 21 | 2019 |
In silico genome analysis reveals the evolution and potential impact of SARS-CoV-2 Omicron structural changes on host immune evasion and antiviral therapeutics D Chauhan, N Chakravarty, AV Jeyachandran, A Jayakarunakaran, ... Viruses 14 (11), 2461, 2022 | 7 | 2022 |
Review on dimensionality reduction techniques D Chauhan, R Mathews Proceeding of the International Conference on Computer Networks, Big Data …, 2020 | 7 | 2020 |
Structural basis for the oligomerization-facilitated NLRP3 activation X Yu, RE Matico, R Miller, D Chauhan, B Van Schoubroeck, K Grauwen, ... Nature Communications 15 (1), 1164, 2024 | 4 | 2024 |