The p65 (RelA) subunit of NF-κB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression BP Ashburner, SD Westerheide, AS Baldwin Jr Molecular and cellular biology, 2001 | 903 | 2001 |
Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1 SD Westerheide, J Anckar, SM Stevens Jr, L Sistonen, RI Morimoto Science 323 (5917), 1063-1066, 2009 | 836 | 2009 |
Heat shock response modulators as therapeutic tools for diseases of protein conformation SD Westerheide, RI Morimoto Journal of Biological Chemistry 280 (39), 33097-33100, 2005 | 634 | 2005 |
Tumor necrosis factor α-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II D Wang, SD Westerheide, JL Hanson, AS Baldwin Journal of Biological Chemistry 275 (42), 32592-32597, 2000 | 589 | 2000 |
Celastrols as Inducers of the Heat Shock Response and Cytoprotection*[boxs] SD Westerheide, JD Bosman, BNA Mbadugha, TLA Kawahara, ... Journal of Biological Chemistry 279 (53), 56053-56060, 2004 | 485 | 2004 |
Benchmarking organic micropollutants in wastewater, recycled water and drinking water with in vitro bioassays BI Escher, M Allinson, R Altenburger, PA Bain, P Balaguer, W Busch, ... Environmental science & technology 48 (3), 1940-1956, 2014 | 463 | 2014 |
Triptolide, an inhibitor of the human heat shock response that enhances stress-induced cell death SD Westerheide, TLA Kawahara, K Orton, RI Morimoto Journal of biological chemistry 281 (14), 9616-9622, 2006 | 269 | 2006 |
Activation of heat shock and antioxidant responses by the natural product celastrol: transcriptional signatures of a thiol-targeted molecule A Trott, JD West, L Klaić, SD Westerheide, RB Silverman, RI Morimoto, ... Molecular biology of the cell 19 (3), 1104-1112, 2008 | 264 | 2008 |
The Putative Oncoprotein Bcl-3 Induces Cyclin D1 To Stimulate G1 Transition SD Westerheide, MW Mayo, V Anest, JL Hanson, AS Baldwin Jr Molecular and cellular biology 21 (24), 8428-8436, 2001 | 216 | 2001 |
Mechanisms of amino acid-mediated lifespan extension in Caenorhabditis elegans C Edwards, J Canfield, N Copes, A Brito, M Rehan, D Lipps, J Brunquell, ... BMC genetics 16, 1-24, 2015 | 197 | 2015 |
The genome-wide role of HSF-1 in the regulation of gene expression in Caenorhabditis elegans J Brunquell, S Morris, Y Lu, F Cheng, SD Westerheide BMC genomics 17, 1-18, 2016 | 163 | 2016 |
PTEN blocks tumor necrosis factor-induced NF-κB-dependent transcription by inhibiting the transactivation potential of the p65 subunit MW Mayo, LV Madrid, SD Westerheide, DR Jones, XJ Yuan, AS Baldwin, ... Journal of Biological Chemistry 277 (13), 11116-11125, 2002 | 160 | 2002 |
Loss of function CHCHD10 mutations in cytoplasmic TDP-43 accumulation and synaptic integrity JAA Woo, T Liu, C Trotter, CC Fang, E De Narvaez, P LePochat, D Maslar, ... Nature communications 8 (1), 15558, 2017 | 114 | 2017 |
The MHC-specific enhanceosome and its role in MHC class I and β2-microglobulin gene transactivation SJP Gobin, M van Zutphen, SD Westerheide, JM Boss, PJ van den Elsen The Journal of Immunology 167 (9), 5175-5184, 2001 | 108 | 2001 |
Heat shock and caloric restriction have a synergistic effect on the heat shock response in a sir2. 1-dependent manner in Caenorhabditis elegans R Raynes, BD Leckey, K Nguyen, SD Westerheide Journal of Biological Chemistry 287 (34), 29045-29053, 2012 | 80 | 2012 |
The SIRT1 modulators AROS and DBC1 regulate HSF1 activity and the heat shock response R Raynes, KM Pombier, K Nguyen, J Brunquell, JE Mendez, ... PloS one 8 (1), e54364, 2013 | 70 | 2013 |
HLA-DMA and HLA-DMB gene expression functions through the conserved SXY region. SD Westerheide, P Louis-Plence, D Ping, XF He, JM Boss Journal of immunology (Baltimore, Md.: 1950) 158 (10), 4812-4821, 1997 | 70 | 1997 |
Interlaboratory comparison of in vitro bioassays for screening of endocrine active chemicals in recycled water AC Mehinto, A Jia, SA Snyder, BS Jayasinghe, ND Denslow, J Crago, ... Water research 83, 303-309, 2015 | 66 | 2015 |
Stress inducibility of SIRT1 and its role in cytoprotection and cancer R Raynes, J Brunquell, SD Westerheide Genes & cancer 4 (3-4), 172-182, 2013 | 63 | 2013 |
The heat shock transcription factor HSF1 induces ovarian cancer epithelial-mesenchymal transition in a 3D spheroid growth model CD Powell, TR Paullin, C Aoisa, CJ Menzie, A Ubaldini, SD Westerheide PLoS One 11 (12), e0168389, 2016 | 49 | 2016 |