Genetic drivers of epigenetic and transcriptional variation in human immune cells L Chen, B Ge, FP Casale, L Vasquez, T Kwan, D Garrido-Martín, S Watt, ... Cell 167 (5), 1398-1414. e24, 2016 | 666 | 2016 |
Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia M Kulis, S Heath, M Bibikova, AC Queirós, A Navarro, G Clot, ... Nature genetics 44 (11), 1236-1242, 2012 | 664 | 2012 |
Whole-genome fingerprint of the DNA methylome during human B cell differentiation M Kulis, A Merkel, S Heath, AC Queirós, RP Schuyler, G Castellano, ... Nature genetics 47 (7), 746-756, 2015 | 314 | 2015 |
Transcriptome characterization by RNA sequencing identifies a major molecular and clinical subdivision in chronic lymphocytic leukemia PG Ferreira, P Jares, D Rico, G Gómez-López, A Martínez-Trillos, ... Genome research 24 (2), 212-226, 2014 | 250 | 2014 |
Increased DNA methylation variability in type 1 diabetes across three immune effector cell types DS Paul, AE Teschendorff, MAN Dang, R Lowe, MI Hawa, S Ecker, ... Nature Communications 7, 13555, 2016 | 159 | 2016 |
Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types S Ecker, L Chen, V Pancaldi, FO Bagger, JM Fernández, ... Genome Biology 18 (1), 18, 2017 | 117 | 2017 |
Epigenetic and Transcriptional Variability Shape Phenotypic Plasticity S Ecker, V Pancaldi, A Valencia, S Beck, DS Paul BioEssays 40 (2), 2018 | 93 | 2018 |
Increased DNA methylation variability in rheumatoid arthritis-discordant monozygotic twins AP Webster, D Plant, S Ecker, F Zufferey, JT Bell, A Feber, DS Paul, ... Genome Medicine 10 (64), 2018 | 79 | 2018 |
Characterization of transcriptional changes in ERG rearrangement-positive prostate cancer identifies the regulation of metabolic sensors such as neuropeptide Y P Massoner, KG Kugler, K Unterberger, R Kuner, LAJ Mueller, M Fälth, ... PloS one 8 (2), e55207, 2013 | 69 | 2013 |
Higher gene expression variability in the more aggressive subtype of chronic lymphocytic leukemia S Ecker, V Pancaldi, D Rico, A Valencia Genome Medicine 7 (8), 2015 | 62 | 2015 |
Genetic perturbation of PU.1 binding and chromatin looping at neutrophil enhancers associates with autoimmune disease S Watt, L Vasquez, K Walter, AL Mann, K Kundu, L Chen, Y Sims, Ecker, ... Nature Communications 12 (2298), 2021 | 35 | 2021 |
Exaggerated IL-17A activity in human in vivo recall responses discriminates active tuberculosis from latent infection and cured disease G Pollara, CT Turner, J Rosenheim, A Chandran, LCK Bell, A Khan, ... Science Translational Medicine 13 (592), 2021 | 34 | 2021 |
The synthetic glucocorticoids prednisolone and dexamethasone regulate the same genes in acute lymphoblastic leukemia cells D Bindreither, S Ecker, B Gschirr, A Kofler, R Kofler, J Rainer BMC genomics 15 (1), 662, 2014 | 32 | 2014 |
Chemotherapy induces canalization of cell state in childhood B-cell precursor acute lymphoblastic leukemia VA Turati, JA Guerra-Assunção, NE Potter, R Gupta, S Ecker, ... Nature Cancer 2 (8), 835-852, 2021 | 31 | 2021 |
Personal Genome Project UK (PGP-UK): a research and citizen science hybrid project in support of personalized medicine PGPUK Consortium BMC Medical Genomics 11 (108), 2018 | 29 | 2018 |
The epigenetic clock: a molecular crystal ball for human aging? S Ecker, S Beck Aging (Albany NY) 11 (2), 817-832, 2019 | 26 | 2019 |
Epigenome-wide association study and epigenetic age acceleration associated with cigarette smoking among Costa Rican adults A Cardenas, S Ecker, RP Fadadu, K Huen, A Orozco, LM McEwen, ... Scientific Reports 12 (1), 1-13, 2022 | 24 | 2022 |
An expedited screening platform for the discovery of anti-ageing compounds in vitro and in vivo C Lujan, EJ Tyler, S Ecker, AP Webster, ER Stead, VE Martinez-Miguel, ... Genome Medicine 16, 2024 | 7* | 2024 |
Sex Differences in Epigenetic Age in Mediterranean High Longevity Regions HR Engelbrecht, SM Merrill, N Gladish, JL Macisaac, DTS Lin, S Ecker, ... Frontiers in Aging, 119, 2022 | 7 | 2022 |
Epigenetic variation taking center stage in immunological research S Ecker, S Beck Epigenomics, 2017 | 6 | 2017 |