Cryo-EM structures of tau filaments from Alzheimer’s disease AWP Fitzpatrick, B Falcon, S He, AG Murzin, G Murshudov, HJ Garringer, ... Nature 547 (7662), 185-190, 2017 | 1826 | 2017 |
Structures of filaments from Pick’s disease reveal a novel tau protein fold B Falcon, W Zhang, A Murzin, G Murshudov, H Garringer, R Vidal, ... Nature 561, 137-140, 2018 | 741 | 2018 |
Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules B Falcon, J Zivanov, W Zhang, AG Murzin, HJ Garringer, R Vidal, ... Nature 568 (7752), 420-423, 2019 | 618 | 2019 |
Structure-based classification of tauopathies Y Shi, W Zhang, Y Yang, AG Murzin, B Falcon, A Kotecha, M van Beers, ... Nature 598 (7880), 359-363, 2021 | 540 | 2021 |
Novel tau filament fold in corticobasal degeneration W Zhang, A Tarutani, KL Newell, AG Murzin, T Matsubara, B Falcon, ... Nature 580 (7802), 283-287, 2020 | 472 | 2020 |
Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer’s and Pick’s diseases W Zhang, B Falcon, AG Murzin, J Fan, RA Crowther, M Goedert, ... Elife 8, e43584, 2019 | 419 | 2019 |
Tau filaments from multiple cases of sporadic and inherited Alzheimer’s disease adopt a common fold B Falcon, W Zhang, M Schweighauser, AG Murzin, R Vidal, HJ Garringer, ... Acta neuropathologica 136 (5), 699-708, 2018 | 313 | 2018 |
Like prions: the propagation of aggregated tau and α-synuclein in neurodegeneration M Goedert, M Masuda-Suzukake, B Falcon Brain 140 (2), 266-278, 2017 | 308 | 2017 |
Cryo-EM structures of amyloid-β 42 filaments from human brains Y Yang, D Arseni, W Zhang, M Huang, S Lövestam, M Schweighauser, ... Science 375 (6577), 167-172, 2022 | 290 | 2022 |
Conformation determines the seeding potencies of native and recombinant Tau aggregates B Falcon, A Cavallini, R Angers, S Glover, TK Murray, L Barnham, ... Journal of biological chemistry 290 (2), 1049-1065, 2015 | 289 | 2015 |
Cryo-EM structures of tau filaments SHW Scheres, W Zhang, B Falcon, M Goedert Current Opinion in Structural Biology 64, 17-25, 2020 | 205 | 2020 |
Structure of pathological TDP-43 filaments from ALS with FTLD D Arseni, M Hasegawa, AG Murzin, F Kametani, M Arai, M Yoshida, ... Nature 601 (7891), 139-143, 2022 | 171 | 2022 |
Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation WA McEwan, B Falcon, M Vaysburd, D Clift, AL Oblak, B Ghetti, ... Proceedings of the National Academy of Sciences 114 (3), 574-579, 2017 | 164 | 2017 |
Short fibrils constitute the major species of seed-competent tau in the brains of mice transgenic for human P301S tau SJ Jackson, C Kerridge, J Cooper, A Cavallini, B Falcon, CV Cella, ... Journal of Neuroscience 36 (3), 762-772, 2016 | 160 | 2016 |
“Prion‐like” templated misfolding in tauopathies F Clavaguera, I Lavenir, B Falcon, S Frank, M Goedert, M Tolnay Brain pathology 23 (3), 342-349, 2013 | 150 | 2013 |
Prion-like mechanisms in the pathogenesis of tauopathies and synucleinopathies M Goedert, B Falcon, F Clavaguera, M Tolnay Current neurology and neuroscience reports 14, 1-11, 2014 | 140 | 2014 |
Cryo-EM structures of tau filaments from Alzheimer’s disease with PET ligand APN-1607 Y Shi, AG Murzin, B Falcon, A Epstein, J Machin, P Tempest, KL Newell, ... Acta neuropathologica 141, 697-708, 2021 | 133 | 2021 |
Galectin-8–mediated selective autophagy protects against seeded tau aggregation B Falcon, J Noad, H McMahon, F Randow, M Goedert Journal of Biological Chemistry 293 (7), 2438-2451, 2018 | 117 | 2018 |
Age-dependent formation of TMEM106B amyloid filaments in human brains M Schweighauser, D Arseni, M Bacioglu, M Huang, S Lövestam, Y Shi, ... Nature 605 (7909), 310-314, 2022 | 116 | 2022 |
Measurement of tau filament fragmentation provides insights into prion-like spreading F Kundel, L Hong, B Falcon, WA McEwan, TCT Michaels, G Meisl, ... ACS chemical neuroscience 9 (6), 1276-1282, 2018 | 84 | 2018 |