From stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications SM Hattangadi, P Wong, L Zhang, J Flygare, HF Lodish Blood, The Journal of the American Society of Hematology 118 (24), 6258-6268, 2011 | 550 | 2011 |
Long noncoding RNA-mediated anti-apoptotic activity in murine erythroid terminal differentiation W Hu, B Yuan, J Flygare, HF Lodish Genes & development 25 (24), 2573-2578, 2011 | 298 | 2011 |
Lentiviral vector transduction of NOD/SCID repopulating cells results in multiple vector integrations per transduced cell: risk of insertional mutagenesis NB Woods, A Muessig, M Schmidt, J Flygare, K Olsson, P Salmon, ... Blood, The Journal of the American Society of Hematology 101 (4), 1284-1289, 2003 | 294 | 2003 |
Human RPS19, the gene mutated in Diamond-Blackfan anemia, encodes a ribosomal protein required for the maturation of 40S ribosomal subunits J Flygare, A Aspesi, JC Bailey, K Miyake, JM Caffrey, S Karlsson, SR Ellis Blood 109 (3), 980-986, 2007 | 240 | 2007 |
HIF1α synergizes with glucocorticoids to promote BFU-E progenitor self-renewal J Flygare, VR Estrada, C Shin, S Gupta, HF Lodish Blood, The Journal of the American Society of Hematology 117 (12), 3435-3444, 2011 | 192 | 2011 |
Deficiency of ribosomal protein S19 in CD34+ cells generated by siRNA blocks erythroid development and mimics defects seen in Diamond-Blackfan anemia J Flygare, T Kiefer, K Miyake, T Utsugisawa, I Hamaguchi, L Da Costa, ... Blood 105 (12), 4627-4634, 2005 | 158 | 2005 |
miR-191 regulates mouse erythroblast enucleation by down-regulating Riok3 and Mxi1 L Zhang, J Flygare, P Wong, B Lim, HF Lodish Genes & development 25 (2), 119-124, 2011 | 149 | 2011 |
Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia P Jaako, J Flygare, K Olsson, R Quere, M Ehinger, A Henson, S Ellis, ... Blood, The Journal of the American Society of Hematology 118 (23), 6087-6096, 2011 | 147 | 2011 |
ZFP36L2 is required for self-renewal of early burst-forming unit erythroid progenitors L Zhang, L Prak, V Rayon-Estrada, P Thiru, J Flygare, B Lim, HF Lodish Nature 499 (7456), 92-96, 2013 | 126 | 2013 |
Diamond-Blackfan anemia: erythropoiesis lost in translation J Flygare, S Karlsson Blood 109 (8), 3152-3154, 2007 | 122 | 2007 |
From stem cell to erythroblast: regulation of red cell production at multiple levels by multiple hormones H Lodish, J Flygare, S Chou IUBMB life 62 (7), 492-496, 2010 | 114 | 2010 |
Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia P Jaako, S Debnath, K Olsson, D Bryder, J Flygare, S Karlsson Blood, The Journal of the American Society of Hematology 120 (11), 2225-2228, 2012 | 93 | 2012 |
Ribosomal protein S19 deficiency leads to reduced proliferation and increased apoptosis but does not affect terminal erythroid differentiation in a cell line model of Diamond … K Miyake, T Utsugisawa, J Flygare, T Kiefer, I Hamaguchi, J Richter, ... Stem Cells 26 (2), 323-329, 2008 | 85 | 2008 |
Development of cellular models for ribosomal protein S19 (RPS19)-deficient Diamond–Blackfan anemia using inducible expression of siRNA against RPS19 K Miyake, J Flygare, T Kiefer, T Utsugisawa, J Richter, Z Ma, ... Molecular Therapy 11 (4), 627-637, 2005 | 73 | 2005 |
Proliferation deficiency of multipotent hematopoietic progenitors in ribosomal protein S19 (RPS19)-deficient diamond–Blackfan anemia improves following RPS19 gene transfer I Hamaguchi, J Flygare, H Nishiura, ACM Brun, A Ooka, T Kiefer, Z Ma, ... Molecular Therapy 7 (5), 613-622, 2003 | 68 | 2003 |
Defining the minimal factors required for erythropoiesis through direct lineage conversion S Capellera-Garcia, J Pulecio, K Dhulipala, K Siva, V Rayon-Estrada, ... Cell reports 15 (11), 2550-2562, 2016 | 59 | 2016 |
Erythropoiesis in the Rps19 disrupted mouse: Analysis of erythropoietin response and biochemical markers for Diamond-Blackfan anemia H Matsson, EJ Davey, AS Fröjmark, K Miyake, T Utsugisawa, J Flygare, ... Blood Cells, Molecules, and Diseases 36 (2), 259-264, 2006 | 51 | 2006 |
Gene therapy of Diamond Blackfan anemia CD34+ cells leads to improved erythroid development and engraftment following transplantation J Flygare, K Olsson, J Richter, S Karlsson Experimental Hematology 36 (11), 1428-1435, 2008 | 47 | 2008 |
Disruption of the 5S RNP–Mdm2 interaction significantly improves the erythroid defect in a mouse model for Diamond-Blackfan anemia P Jaako, S Debnath, K Olsson, Y Zhang, J Flygare, MS Lindström, ... Leukemia 29 (11), 2221-2229, 2015 | 41 | 2015 |
Fetal hepatic progenitors support long-term expansion of hematopoietic stem cells S Chou, J Flygare, HF Lodish Experimental hematology 41 (5), 479-490. e4, 2013 | 40 | 2013 |