A highly specific SpCas9 variant is identified by in vivo screening in yeast A Casini, M Olivieri, G Petris, C Montagna, G Reginato, G Maule, ... Nature biotechnology 36 (3), 265-271, 2018 | 505 | 2018 |
VSV-G-Enveloped Vesicles for Traceless Delivery of CRISPR-Cas9 C Montagna, G Petris, A Casini, G Maule, GM Franceschini, I Zanella, ... Molecular Therapy-Nucleic Acids 12, 453-462, 2018 | 106 | 2018 |
Hit and go CAS9 delivered through a lentiviral based self-limiting circuit G Petris, A Casini, C Montagna, F Lorenzin, D Prandi, A Romanel, ... Nature communications 8, 15334, 2017 | 101 | 2017 |
Allele specific repair of splicing mutations in cystic fibrosis through AsCas12a genome editing G Maule, A Casini, C Montagna, AS Ramalho, K De Boeck, Z Debyser, ... Nature communications 10 (1), 3556, 2019 | 90 | 2019 |
Tobacco Etch Virus protease: A shortcut across biotechnologies F Cesaratto, OR Burrone, G Petris Journal of biotechnology 231, 239-249, 2016 | 75 | 2016 |
Pharmacological inactivation of the prion protein by targeting a folding intermediate G Spagnolli, T Massignan, A Astolfi, S Biggi, M Rigoli, P Brunelli, ... Communications Biology 4 (1), 62, 2021 | 42 | 2021 |
Engineered tobacco etch virus (TEV) protease active in the secretory pathway of mammalian cells F Cesaratto, A López-Requena, OR Burrone, G Petris Journal of biotechnology 212, 159-166, 2015 | 41 | 2015 |
Mechanism-based traps enable protease and hydrolase substrate discovery S Tang, AT Beattie, L Kafkova, G Petris, N Huguenin-Dezot, M Fiedler, ... Nature 602 (7898), 701-707, 2022 | 35 | 2022 |
Thermally driven membrane phase transitions enable content reshuffling in primitive cells R Rubio-Sánchez, DK O’Flaherty, A Wang, F Coscia, G Petris, ... Journal of the American Chemical Society 143 (40), 16589-16598, 2021 | 34 | 2021 |
Inherited determinants of early recurrent somatic mutations in prostate cancer A Romanel, S Garritano, B Stringa, M Blattner, D Dalfovo, D Chakravarty, ... Nature communications 8 (1), 48, 2017 | 34 | 2017 |
Refactored genetic codes enable bidirectional genetic isolation JF Zürcher, WE Robertson, T Kappes, G Petris, TS Elliott, GPC Salmond, ... Science 378 (6619), 516-523, 2022 | 33 | 2022 |
Efficient detection of proteins retro-translocated from the ER to the cytosol by in vivo biotinylation G Petris, L Vecchi, M Bestagno, OR Burrone PLoS One 6 (8), e23712, 2011 | 33 | 2011 |
The VCP/p97 and YOD1 proteins have different substrate-dependent activities in endoplasmic reticulum-associated degradation (ERAD) L Sasset, G Petris, F Cesaratto, OR Burrone Journal of Biological Chemistry 290 (47), 28175-28188, 2015 | 28 | 2015 |
CD4 and BST-2/tetherin proteins retro-translocate from endoplasmic reticulum to cytosol as partially folded and multimeric molecules G Petris, A Casini, L Sasset, F Cesaratto, M Bestagno, A Cereseto, ... Journal of Biological Chemistry 289 (1), 1-12, 2014 | 28 | 2014 |
CRISPR-Csy4-mediated editing of rotavirus double-stranded RNA genome G Papa, L Venditti, L Braga, E Schneider, M Giacca, G Petris, OR Burrone Cell Reports 32 (13), 2020 | 27 | 2020 |
Calcium cytotoxicity sensitizes prostate cancer cells to standard-of-care treatments for locally advanced tumors A Alaimo, M Lorenzoni, P Ambrosino, A Bertossi, A Bisio, A Macchia, ... Cell death & disease 11 (12), 1039, 2020 | 22 | 2020 |
New tags for recombinant protein detection and O-glycosylation reporters G Petris, M Bestagno, F Arnoldi, OR Burrone PloS one 9 (5), e96700, 2014 | 21 | 2014 |
BiP/GRP78 Mediates ERAD Targeting of Proteins Produced by Membrane-Bound Ribosomes Stalled at the STOP-Codon F Cesaratto, L Sasset, MP Myers, A Re, G Petris, OR Burrone Journal of molecular biology 431 (2), 123-141, 2019 | 18 | 2019 |
Selective targeting of proteins within secretory pathway for endoplasmic reticulum-associated degradation L Vecchi, G Petris, M Bestagno, OR Burrone Journal of Biological Chemistry 287 (24), 20007-20015, 2012 | 18 | 2012 |
LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice R Prakasam, A Bonadiman, R Andreotti, E Zuccaro, D Dalfovo, ... Nature Communications 14 (1), 603, 2023 | 14 | 2023 |