Current trends and challenges in the clinical translation of nanoparticulate nanomedicines: pathways for translational development and commercialization S Hua, MBC De Matos, JM Metselaar, G Storm Frontiers in pharmacology 9, 790, 2018 | 777 | 2018 |
Complete remission of experimental arthritis by joint targeting of glucocorticoids with long‐circulating liposomes JM Metselaar, MHM Wauben, JPA Wagenaar‐Hilbers, OC Boerman, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2003 | 361 | 2003 |
Improving solubility and chemical stability of natural compounds for medicinal use by incorporation into liposomes M Coimbra, B Isacchi, L van Bloois, JS Torano, A Ket, X Wu, F Broere, ... International journal of pharmaceutics 416 (2), 433-442, 2011 | 353 | 2011 |
Drug targeting by long‐circulating liposomal glucocorticosteroids increases therapeutic efficacy in a model of multiple sclerosis J Schmidt, JM Metselaar, MHM Wauben, KV Toyka, G Storm, R Gold Brain 126 (8), 1895-1904, 2003 | 256 | 2003 |
Role of complement activation in hypersensitivity reactions to doxil and hynic PEG liposomes: experimental and clinical studies J Szebeni, L Baranyi, S Savay, J Milosevits, R Bunger, P Laverman, ... Journal of liposome research 12 (1-2), 165-172, 2002 | 248 | 2002 |
Multimodal clinical imaging to longitudinally assess a nanomedical anti-inflammatory treatment in experimental atherosclerosis ME Lobatto, ZA Fayad, S Silvera, E Vucic, C Calcagno, V Mani, ... Molecular pharmaceutics 7 (6), 2020-2029, 2010 | 215 | 2010 |
A Novel Family of l-Amino Acid-Based Biodegradable Polymer−Lipid Conjugates for the Development of Long-Circulating Liposomes with Effective Drug-Targeting … JM Metselaar, P Bruin, LWT de Boer, T de Vringer, C Snel, C Oussoren, ... Bioconjugate chemistry 14 (6), 1156-1164, 2003 | 208 | 2003 |
Challenges in nanomedicine clinical translation JM Metselaar, T Lammers Drug delivery and translational research 10, 721-725, 2020 | 194 | 2020 |
Dexamethasone nanomedicines for COVID-19 T Lammers, AM Sofias, R Van der Meel, R Schiffelers, G Storm, F Tacke, ... Nature nanotechnology 15 (8), 622-624, 2020 | 173 | 2020 |
Prednisolone-containing liposomes accumulate in human atherosclerotic macrophages upon intravenous administration FM van der Valk, DF van Wijk, ME Lobatto, HJ Verberne, G Storm, ... Nanomedicine: nanotechnology, biology and medicine 11 (5), 1039-1046, 2015 | 167 | 2015 |
Size-isolation of superparamagnetic iron oxide nanoparticles improves MRI, MPI and hyperthermia performance SM Dadfar, D Camozzi, M Darguzyte, K Roemhild, P Varvarà, J Metselaar, ... Journal of nanobiotechnology 18, 1-13, 2020 | 161 | 2020 |
Liposomal drug formulations in the treatment of rheumatoid arthritis JM van den Hoven, SR Van Tomme, JM Metselaar, B Nuijen, JH Beijnen, ... Molecular pharmaceutics 8 (4), 1002-1015, 2011 | 157 | 2011 |
Nanomedicines for inflammatory arthritis: head-to-head comparison of glucocorticoid-containing polymers, micelles, and liposomes L Quan, Y Zhang, BJ Crielaard, A Dusad, SM Lele, CJF Rijcken, ... ACS nano 8 (1), 458-466, 2014 | 151 | 2014 |
Liposome-encapsulated prednisolone phosphate inhibits growth of established tumors in mice RM Schiffelers, JM Metselaar, MHAM Fens, APCA Janssen, G Molema, ... Neoplasia 7 (2), 118-127, 2005 | 147 | 2005 |
Liposomes in the treatment of inflammatory disorders JM Metselaar, G Storm Expert opinion on drug delivery 2 (3), 465-476, 2005 | 144 | 2005 |
Atherosclerotic plaque targeting mechanism of long-circulating nanoparticles established by multimodal imaging ME Lobatto, C Calcagno, A Millon, ML Senders, F Fay, PM Robson, ... ACS nano 9 (2), 1837-1847, 2015 | 133 | 2015 |
Liposome encapsulated berberine treatment attenuates cardiac dysfunction after myocardial infarction IE Allijn, BMS Czarny, X Wang, SY Chong, M Weiler, AE Da Silva, ... Journal of controlled release 247, 127-133, 2017 | 130 | 2017 |
Poly (amino acid) s: promising enzymatically degradable stealth coatings for liposomes B Romberg, JM Metselaar, L Baranyi, CJ Snel, R Bünger, WE Hennink, ... International journal of pharmaceutics 331 (2), 186-189, 2007 | 120 | 2007 |
Antitumor activity of liposomal prednisolone phosphate depends on the presence of functional tumor-associated macrophages in tumor tissue M Banciu, JM Metselaar, RM Schiffelers, G Storm Neoplasia 10 (2), 108-117, 2008 | 113 | 2008 |
Metallodrugs in cancer nanomedicine Q Peña, A Wang, O Zaremba, Y Shi, HW Scheeren, JM Metselaar, ... Chemical society reviews 51 (7), 2544-2582, 2022 | 103 | 2022 |