Enhancing CD8+ T cell fatty acid catabolism within a metabolically challenging tumor microenvironment increases the efficacy of melanoma immunotherapy Y Zhang, R Kurupati, L Liu, XY Zhou, G Zhang, A Hudaihed, F Filisio, ... Cancer cell 32 (3), 377-391. e9, 2017 | 475 | 2017 |
Quantitative analysis of NAD synthesis-breakdown fluxes L Liu, X Su, WJ Quinn, S Hui, K Krukenberg, DW Frederick, P Redpath, ... Cell metabolism 27 (5), 1067-1080. e5, 2018 | 455 | 2018 |
Macrophage de novo NAD+ synthesis specifies immune function in aging and inflammation PS Minhas, L Liu, PK Moon, AU Joshi, C Dove, S Mhatre, K Contrepois, ... Nature immunology 20 (1), 50-63, 2019 | 369 | 2019 |
Loss of NAD homeostasis leads to progressive and reversible degeneration of skeletal muscle DW Frederick, E Loro, L Liu, A Davila, K Chellappa, IM Silverman, ... Cell metabolism 24 (2), 269-282, 2016 | 340 | 2016 |
Restoring metabolism of myeloid cells reverses cognitive decline in ageing PS Minhas, A Latif-Hernandez, MR McReynolds, AS Durairaj, Q Wang, ... Nature 590 (7844), 122-128, 2021 | 321 | 2021 |
Human Phosphoglycerate Dehydrogenase Produces the Oncometabolite d-2-Hydroxyglutarate J Fan, X Teng, L Liu, KR Mattaini, RE Looper, MG Vander Heiden, ... ACS chemical biology 10 (2), 510-516, 2015 | 190 | 2015 |
Nicotinamide adenine dinucleotide is transported into mammalian mitochondria A Davila, L Liu, K Chellappa, P Redpath, E Nakamaru-Ogiso, LM Paolella, ... Elife 7, e33246, 2018 | 146 | 2018 |
Malic enzyme tracers reveal hypoxia-induced switch in adipocyte NADPH pathway usage L Liu, S Shah, J Fan, JO Park, KE Wellen, JD Rabinowitz Nature chemical biology 12 (5), 345-352, 2016 | 133 | 2016 |
Peripheral TREM1 responses to brain and intestinal immunogens amplify stroke severity Q Liu, EM Johnson, RK Lam, Q Wang, H Bo Ye, EN Wilson, PS Minhas, ... Nature immunology 20 (8), 1023-1034, 2019 | 125 | 2019 |
Chemical basis for deuterium labeling of fat and NADPH Z Zhang, L Chen, L Liu, X Su, JD Rabinowitz Journal of the American Chemical Society 139 (41), 14368-14371, 2017 | 96 | 2017 |
Multi-modal molecule structure–text model for text-based retrieval and editing S Liu, W Nie, C Wang, J Lu, Z Qiao, L Liu, J Tang, C Xiao, A Anandkumar Nature Machine Intelligence 5 (12), 1447-1457, 2023 | 85 | 2023 |
Metabolic profiling reveals a dependency of human metastatic breast cancer on mitochondrial serine and one-carbon unit metabolism AM Li, GS Ducker, Y Li, JA Seoane, Y Xiao, S Melemenidis, Y Zhou, L Liu, ... Molecular Cancer Research 18 (4), 599-611, 2022 | 72 | 2022 |
Carbon nanotube-assisted optical activation of TGF-β signalling by near-infrared light L Lin, L Liu, B Zhao, R Xie, W Lin, H Li, Y Li, M Shi, YG Chen, TA Springer, ... Nature Nanotechnology 10 (5), 465-471, 2015 | 63 | 2015 |
Zinc finger antiviral protein inhibits murine gammaherpesvirus 68 M2 expression and regulates viral latency in cultured cells Y Xuan, L Liu, S Shen, H Deng, G Gao Journal of virology 86 (22), 12431-12434, 2012 | 32 | 2012 |
Chatgpt-powered conversational drug editing using retrieval and domain feedback S Liu, J Wang, Y Yang, C Wang, L Liu, H Guo, C Xiao arXiv preprint arXiv:2305.18090, 2023 | 26 | 2023 |
Live-cell imaging of NADPH production from specific pathways S Hong, T Chen, L Liu, C Cao, F Lv, JD Rabinowitz, Y Huang, X Chen CCS Chemistry 3 (6), 1642-1648, 2021 | 7 | 2021 |
Conversational drug editing using retrieval and domain feedback S Liu, J Wang, Y Yang, C Wang, L Liu, H Guo, C Xiao The Twelfth International Conference on Learning Representations, 2024 | 4 | 2024 |
O4‐02‐05: DE NOVO NAD+ SYNTHESIS RESCUES NEUROINFLAMMATION AND ALZHEIMER'S DISEASE PHENOTYPES: MODULATING IMMUNE CELL RESPONSES AND MITOCHONDRIAL BIOENERGETICS PS Minhas, L Liu, PK Moon, SD Mhatre, Q Wang, M Coronado, ... Alzheimer's & Dementia 14 (7S_Part_26), P1403-P1404, 2018 | 1 | 2018 |
Quantitative Analysis of Redox Metabolism L Liu Princeton University, 2018 | | 2018 |
Fatty acid metabolism is essential to maintain functions of CD8+ T cells within a hypoxic and hypoglycemic tumor microenvironment Y Zhang, L Liu, R Kurupati, X Zhou, J Rabinowitz, H Ertl The Journal of Immunology 196 (1_Supplement), 144.1-144.1, 2016 | | 2016 |