Mechanisms of leptin action and leptin resistance MG Myers, MA Cowley, H Münzberg Annu. Rev. Physiol. 70 (1), 537-556, 2008 | 1372 | 2008 |
Phosphatidylinositol 3′‐kinase is activated by association with IRS‐1 during insulin stimulation. JM Backer, MG Myers Jr, SE Shoelson, DJ Chin, XJ Sun, M Miralpeix, ... The EMBO journal 11 (9), 3469-3479, 1992 | 1267 | 1992 |
STAT3 signalling is required for leptin regulation of energy balance but not reproduction SH Bates, WH Stearns, TA Dundon, M Schubert, AWK Tso, Y Wang, ... Nature 421 (6925), 856-859, 2003 | 1234 | 2003 |
Role of IRS-2 in insulin and cytokine signalling XJ Sun, LM Wang, Y Zhang, L Yenush, MG Myers Jr, E Glasheen, ... Nature 377 (6545), 173-177, 1995 | 1165 | 1995 |
Obesity and leptin resistance: distinguishing cause from effect MG Myers, RL Leibel, RJ Seeley, MW Schwartz Trends in Endocrinology & Metabolism 21 (11), 643-651, 2010 | 1072 | 2010 |
Activation of downstream signals by the long form of the leptin receptor AS Banks, SM Davis, SH Bates, MG Myers Journal of Biological Chemistry 275 (19), 14563-14572, 2000 | 1041 | 2000 |
Endoplasmic reticulum stress plays a central role in development of leptin resistance L Ozcan, AS Ergin, A Lu, J Chung, S Sarkar, D Nie, MG Myers, U Ozcan Cell metabolism 9 (1), 35-51, 2009 | 1008 | 2009 |
The SH2/SH3 domain‐containing protein GRB2 interacts with tyrosine‐phosphorylated IRS1 and Shc: implications for insulin control of ras signalling. EY Skolnik, CH Lee, A Batzer, LM Vicentini, M Zhou, R Daly, MJ Myers Jr, ... The EMBO journal 12 (5), 1929-1936, 1993 | 864 | 1993 |
Molecular and anatomical determinants of central leptin resistance H Münzberg, MG Myers Jr Nature neuroscience 8 (5), 566-570, 2005 | 723 | 2005 |
Key enzyme in leptin-induced anorexia KD Niswender, GJ Morton, WH Stearns, CJ Rhodes, MG Myers Jr, ... Nature 413 (6858), 794-795, 2001 | 710 | 2001 |
SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985 C Bjørbæk, HJ Lavery, SH Bates, RK Olson, SM Davis, JS Flier, MG Myers Journal of Biological Chemistry 275 (51), 40649-40657, 2000 | 710 | 2000 |
IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85. MG Myers Jr, JM Backer, XJ Sun, S Shoelson, P Hu, J Schlessinger, ... Proceedings of the National Academy of Sciences 89 (21), 10350-10354, 1992 | 662 | 1992 |
Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1 XJ Sun, DL Crimmins, MG Myers Jr, M Miralpeix, MF White Molecular and cellular biology 13 (12), 7418-7428, 1993 | 625 | 1993 |
Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia KD Niswender, CD Morrison, DJ Clegg, R Olson, DG Baskin, MG Myers Jr, ... Diabetes 52 (2), 227-231, 2003 | 567 | 2003 |
Leptin receptor signaling and the regulation of mammalian physiology MG Myers Recent progress in hormone research 59, 287-304, 2004 | 540 | 2004 |
Characterization of signal transduction and glucose transport in skeletal muscle from type 2 diabetic patients. A Krook, M Björnholm, D Galuska, XJ Jiang, R Fahlman, MG Myers Jr, ... Diabetes 49 (2), 284-292, 2000 | 510 | 2000 |
IRS-2 pathways integrate female reproduction and energy homeostasis DJ Burks, JF de Mora, M Schubert, DJ Withers, MG Myers, HH Towery, ... Nature 407 (6802), 377-382, 2000 | 499 | 2000 |
Leptin acts via leptin receptor-expressing lateral hypothalamic neurons to modulate the mesolimbic dopamine system and suppress feeding GM Leinninger, YH Jo, RL Leshan, GW Louis, H Yang, JG Barrera, ... Cell metabolism 10 (2), 89-98, 2009 | 496 | 2009 |
IRS-1: essential for insulin-and IL-4-stimulated mitogenesis in hematopoietic cells LM Wang, MG Myers Jr, XJ Sun, SA Aaronson, M White, JH Pierce Science 261 (5128), 1591-1594, 1993 | 485 | 1993 |
Insulin signal transduction and the IRS proteins MG Myers, MF White Annual review of pharmacology and toxicology 36 (1), 615-658, 1996 | 463 | 1996 |