Structure of a modular polyketide synthase S Dutta, JR Whicher, DA Hansen, WA Hale, JA Chemler, GR Congdon, ... Nature 510 (7506), 512-517, 2014 | 390 | 2014 |
Structural rearrangements of a polyketide synthase module during its catalytic cycle JR Whicher, S Dutta, DA Hansen, WA Hale, JA Chemler, AM Dosey, ... Nature 510 (7506), 560-564, 2014 | 226 | 2014 |
Palladium-catalyzed synthesis of tetrahydrofurans from γ-hydroxy terminal alkenes: scope, limitations, and stereoselectivity MB Hay, AR Hardin, JP Wolfe The Journal of organic chemistry 70 (8), 3099-3107, 2005 | 133 | 2005 |
Biocatalytic site-and enantioselective oxidative dearomatization of phenols SA Baker Dockrey, AL Lukowski, MR Becker, ARH Narayan Nature chemistry 10 (2), 119-125, 2018 | 130 | 2018 |
Scalable biocatalytic C–H oxyfunctionalization reactions S Chakrabarty, Y Wang, JC Perkins, ARH Narayan Chemical Society Reviews 49 (22), 8137-8155, 2020 | 124 | 2020 |
Enzymatic hydroxylation of an unactivated methylene C–H bond guided by molecular dynamics simulations ARH Narayan, G Jiménez-Osés, P Liu, S Negretti, W Zhao, MM Gilbert, ... Nature chemistry 7 (8), 653-660, 2015 | 124 | 2015 |
Electronic effects in the Pt-catalyzed cycloisomerization of propargylic esters: Synthesis of 2, 3-disubstituted indolizines as a mechanistic probe AR Hardin, R Sarpong Organic Letters 9 (22), 4547-4550, 2007 | 103 | 2007 |
State-of-the-art biocatalysis JB Pyser, S Chakrabarty, EO Romero, ARH Narayan ACS central science 7 (7), 1105-1116, 2021 | 102 | 2021 |
Broadening the scope of biocatalytic C–C bond formation LE Zetzsche, ARH Narayan Nature Reviews Chemistry 4 (7), 334-346, 2020 | 89 | 2020 |
Biocatalytic oxidative cross-coupling reactions for biaryl bond formation LE Zetzsche, JA Yazarians, S Chakrabarty, ME Hinze, LAM Murray, ... Nature 603 (7899), 79-85, 2022 | 88 | 2022 |
Rapid construction of the cortistatin pentacyclic core EM Simmons, AR Hardin, X Guo, R Sarpong Angewandte Chemie 120 (35), 6752-6755, 2008 | 88 | 2008 |
Directing group-controlled regioselectivity in an enzymatic C–H bond oxygenation S Negretti, ARH Narayan, KC Chiou, PM Kells, JL Stachowski, ... Journal of the American Chemical Society 136 (13), 4901-4904, 2014 | 78 | 2014 |
Biocatalytic synthesis of pikromycin, methymycin, neomethymycin, novamethymycin, and ketomethymycin DA Hansen, CM Rath, EB Eisman, ARH Narayan, JD Kittendorf, ... Journal of the American Chemical Society 135 (30), 11232-11238, 2013 | 77 | 2013 |
Chemoenzymatic total synthesis of natural products S Chakrabarty, EO Romero, JB Pyser, JA Yazarians, ARH Narayan Accounts of chemical research 54 (6), 1374-1384, 2021 | 76 | 2021 |
Protic Solvent Mediated Cycloisomerization of Quinoline and Isoquinoline Propargylic Carbinols: Syntheses of (±)-3-Demethoxyerythratidinone and (±)-Cocculidine ST Heller, T Kiho, ARH Narayan, R Sarpong Angewandte Chemie (International ed. in English) 52 (42), 11129, 2013 | 65 | 2013 |
Formal total synthesis of (±)-cortistatin A EM Simmons, AR Hardin-Narayan, X Guo, R Sarpong Tetrahedron 66 (26), 4696-4700, 2010 | 65 | 2010 |
C–H hydroxylation in paralytic shellfish toxin biosynthesis AL Lukowski, DC Ellinwood, ME Hinze, RJ DeLuca, J Du Bois, S Hall, ... Journal of the American Chemical Society 140 (37), 11863-11869, 2018 | 61 | 2018 |
Lewis acid catalyzed carbonyl–olefin metathesis JR Ludwig, CS Schindler Synlett 28 (13), 1501-1509, 2017 | 60 | 2017 |
Stereodivergent, chemoenzymatic synthesis of azaphilone natural products JB Pyser, SA Baker Dockrey, AR Benítez, LA Joyce, RA Wiscons, ... Journal of the American Chemical Society 141 (46), 18551-18559, 2019 | 56 | 2019 |
Chemistry of a unique polyketide-like synthase SW Chun, ME Hinze, MA Skiba, ARH Narayan Journal of the American Chemical Society 140 (7), 2430-2433, 2018 | 55 | 2018 |