Insulin resistance is a cellular antioxidant defense mechanism KL Hoehn, AB Salmon, C Hohnen-Behrens, N Turner, AJ Hoy, ... Proceedings of the National Academy of Sciences 106 (42), 17787-17792, 2009 | 612 | 2009 |
The high reactivity of peroxiredoxin 2 with H2O2 is not reflected in its reaction with other oxidants and thiol reagents AV Peskin, FM Low, LN Paton, GJ Maghzal, MB Hampton, ... Journal of Biological Chemistry 282 (16), 11885-11892, 2007 | 451 | 2007 |
NAD deficiency, congenital malformations, and niacin supplementation H Shi, A Enriquez, M Rapadas, EMMA Martin, R Wang, J Moreau, CK Lim, ... New England Journal of Medicine 377 (6), 544-552, 2017 | 234 | 2017 |
Reactivation of dihydroorotate dehydrogenase-driven pyrimidine biosynthesis restores tumor growth of respiration-deficient cancer cells M Bajzikova, J Kovarova, AR Coelho, S Boukalova, S Oh, K Rohlenova, ... Cell metabolism 29 (2), 399-416. e10, 2019 | 221 | 2019 |
The roles of myeloperoxidase in coronary artery disease and its potential implication in plaque rupture N Teng, GJ Maghzal, J Talib, I Rashid, AK Lau, R Stocker Redox Report 22 (2), 51-73, 2017 | 207 | 2017 |
Detection of reactive oxygen species derived from the family of NOX NADPH oxidases GJ Maghzal, KH Krause, R Stocker, V Jaquet Free Radical Biology and Medicine 53 (10), 1903-1918, 2012 | 189 | 2012 |
Pharmacological characterization of the seven human NOX isoforms and their inhibitors F Augsburger, A Filippova, D Rasti, T Seredenina, M Lam, G Maghzal, ... Redox biology 26, 101272, 2019 | 159 | 2019 |
Dietary quercetin attenuates oxidant-induced endothelial dysfunction and atherosclerosis in apolipoprotein E knockout mice fed a high-fat diet: a critical role for heme oxygenase-1 Y Shen, NC Ward, JM Hodgson, IB Puddey, Y Wang, D Zhang, ... Free Radical Biology and Medicine 65, 908-915, 2013 | 150 | 2013 |
Reactive oxygen-related diseases: therapeutic targets and emerging clinical indications AI Casas, VTV Dao, A Daiber, GJ Maghzal, F Di Lisa, N Kaludercic, ... Antioxidants & redox signaling 23 (14), 1171-1185, 2015 | 148 | 2015 |
The lipocalin α1-microglobulin has radical scavenging activity B Akerstrom, GJ Maghzal, CC Winterbourn, AJ Kettle Journal of Biological Chemistry 282 (43), 31493-31503, 2007 | 144 | 2007 |
Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation DJ Fazakerley, AY Minard, JR Krycer, KC Thomas, J Stöckli, DJ Harney, ... Journal of Biological Chemistry 293 (19), 7315-7328, 2018 | 129 | 2018 |
Near-infrared autofluorescence induced by intraplaque hemorrhage and heme degradation as marker for high-risk atherosclerotic plaques NM Htun, YC Chen, B Lim, T Schiller, GJ Maghzal, AL Huang, KD Elgass, ... Nature communications 8 (1), 75, 2017 | 128 | 2017 |
Limited role for the bilirubin-biliverdin redox amplification cycle in the cellular antioxidant protection by biliverdin reductase GJ Maghzal, MC Leck, E Collinson, C Li, R Stocker Journal of Biological Chemistry 284 (43), 29251-29259, 2009 | 126 | 2009 |
Myeloperoxidase is a potential molecular imaging and therapeutic target for the identification and stabilization of high-risk atherosclerotic plaque I Rashid, GJ Maghzal, YC Chen, D Cheng, J Talib, D Newington, M Ren, ... European heart journal 39 (35), 3301-3310, 2018 | 121 | 2018 |
Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance DJ Fazakerley, R Chaudhuri, P Yang, GJ Maghzal, KC Thomas, JR Krycer, ... Elife 7, e32111, 2018 | 118 | 2018 |
Tryptophan metabolism to kynurenine is a potential novel contributor to hypotension in human sepsis D Changsirivathanathamrong, Y Wang, D Rajbhandari, GJ Maghzal, ... Critical care medicine 39 (12), 2678-2683, 2011 | 117 | 2011 |
Inhibition of MPO (myeloperoxidase) attenuates endothelial dysfunction in mouse models of vascular inflammation and atherosclerosis D Cheng, J Talib, CP Stanley, I Rashid, E Michaëlsson, EL Lindstedt, ... Arteriosclerosis, thrombosis, and vascular biology 39 (7), 1448-1457, 2019 | 115 | 2019 |
Novel fibrinogen γ375 Arg→ Trp mutation (fibrinogen Aguadilla) causes hepatic endoplasmic reticulum storage and hypofibrinogenemia SO Brennan, G Maghzal, BL Shneider, R Gordon, MS Magid, PM George Hepatology 36 (3), 652-658, 2002 | 112 | 2002 |
Flavonoid‐rich apple improves endothelial function in individuals at risk for cardiovascular disease: a randomized controlled clinical trial NP Bondonno, CP Bondonno, LC Blekkenhorst, MJ Considine, ... Molecular Nutrition & Food Research 62 (3), 1700674, 2018 | 108 | 2018 |
Cytochrome b5, not superoxide anion radical, is a major reductant of indoleamine 2, 3-dioxygenase in human cells GJ Maghzal, SR Thomas, NH Hunt, R Stocker Journal of Biological Chemistry 283 (18), 12014-12025, 2008 | 103 | 2008 |