Mitochondrial and metabolic dysfunction in ageing and age-related diseases JA Amorim, G Coppotelli, AP Rolo, CM Palmeira, JM Ross, DA Sinclair Nature Reviews Endocrinology 18 (4), 243-258, 2022 | 353 | 2022 |
Germline mitochondrial DNA mutations aggravate ageing and can impair brain development JM Ross, JB Stewart, E Hagström, S Brené, A Mourier, G Coppotelli, ... Nature 501 (7467), 412-415, 2013 | 294 | 2013 |
High brain lactate is a hallmark of aging and caused by a shift in the lactate dehydrogenase A/B ratio JM Ross, J Öberg, S Brené, G Coppotelli, M Terzioglu, K Pernold, ... Proceedings of the National Academy of Sciences 107 (46), 20087-20092, 2010 | 285 | 2010 |
Loss of epigenetic information as a cause of mammalian aging JH Yang, M Hayano, PT Griffin, JA Amorim, MS Bonkowski, ... Cell 186 (2), 305-326. e27, 2023 | 279 | 2023 |
Mitochondrial and ubiquitin proteasome system dysfunction in ageing and disease: two sides of the same coin? JM Ross, L Olson, G Coppotelli International journal of molecular sciences 16 (8), 19458-19476, 2015 | 128 | 2015 |
The role of type 1 and type 2 5′-deiodinase in the pathophysiology of the 3, 5, 3′-triiodothyronine toxicosis of McCune-Albright syndrome FS Celi, G Coppotelli, A Chidakel, M Kelly, BA Brillante, T Shawker, ... The Journal of Clinical Endocrinology & Metabolism 93 (6), 2383-2389, 2008 | 75 | 2008 |
The Thr92Ala deiodinase type 2 (DIO2) variant is not associated with type 2 diabetes or indices of insulin resistance in the old order of Amish D Mentuccia, MJ Thomas, G Coppotelli, LJ Reinhart, BD Mitchell, ... Thyroid 15 (11), 1223-1227, 2005 | 67 | 2005 |
Maternally transmitted mitochondrial DNA mutations can reduce lifespan JM Ross, G Coppotelli, BJ Hoffer, L Olson Scientific reports 4 (1), 6569, 2014 | 65 | 2014 |
The Epstein–Barr virus nuclear antigen-1 reprograms transcription by mimicry of high mobility group A proteins G Coppotelli, N Mughal, S Callegari, R Sompallae, L Caja, ... Nucleic acids research 41 (5), 2950-2962, 2013 | 47 | 2013 |
Oxidized low-density lipoproteins impair endothelial function by inhibiting non-genomic action of thyroid hormone–mediated nitric oxide production in human endothelial cells R Vicinanza, G Coppotelli, C Malacrino, T Nardo, B Buchetti, L Lenti, ... Thyroid 23 (2), 231-238, 2013 | 42 | 2013 |
DNA break-induced epigenetic drift as a cause of mammalian aging M Hayano, JH Yang, MS Bonkowski, JA Amorim, JM Ross, G Coppotelli, ... BioRxiv, 808659, 2019 | 41 | 2019 |
Functional characterization of the 258 A/G (D2-ORFa-Gly3Asp) human type-2 deiodinase polymorphism: a naturally occurring variant increases the enzymatic activity by removing a … G Coppotelli, A Summers, A Chidakel, JM Ross, FS Celi Thyroid 16 (7), 625-632, 2006 | 37 | 2006 |
Herpes virus deneddylases interrupt the cullin-RING ligase neddylation cycle by inhibiting the binding of CAND1 S Gastaldello, S Callegari, G Coppotelli, S Hildebrand, M Song, ... Journal of molecular cell biology 4 (4), 242-251, 2012 | 35 | 2012 |
Ubiquitin C‐terminal hydrolase‐L1 interacts with adhesion complexes and promotes cell migration, survival, and anchorage independent growth T Frisan, G Coppotelli, R Dryselius, MG Masucci The FASEB Journal 26 (12), 5060-5070, 2012 | 33 | 2012 |
Voluntary exercise normalizes the proteomic landscape in muscle and brain and improves the phenotype of progeroid mice JM Ross, G Coppotelli, RM Branca, KM Kim, J Lehtiö, DA Sinclair, L Olson Aging Cell 18 (6), e13029, 2019 | 30 | 2019 |
The ubiquitin C‐terminal hydrolase UCH‐L1 promotes bacterial invasion by altering the dynamics of the actin cytoskeleton E Bassères, G Coppotelli, T Pfirrmann, JB Andersen, M Masucci, T Frisan Cellular microbiology 12 (11), 1622-1633, 2010 | 29 | 2010 |
Comparison of extracellular matrix and apoptotic markers between benign lesions and carcinomas in human breast F Vasaturo, E Sallusti, A Gradilone, C Malacrino, T Nardo, G Avagnano, ... International journal of oncology 27 (4), 1005-1011, 2005 | 25 | 2005 |
Histological-based stainings using free-floating tissue sections EM Potts, G Coppotelli, JM Ross JoVE (Journal of Visualized Experiments), e61622, 2020 | 22 | 2020 |
Thioredoxin 80-activated-monocytes (TAMs) inhibit the replication of intracellular pathogens X Cortes-Bratti, E Basseres, F Herrera-Rodriguez, S Botero-Kleiven, ... PLoS One 6 (2), e16960, 2011 | 21 | 2011 |
Acute exposure to microplastics induced changes in behavior and inflammation in young and old mice L Gaspar, S Bartman, G Coppotelli, JM Ross International Journal of Molecular Sciences 24 (15), 12308, 2023 | 18 | 2023 |