The human splicing code reveals new insights into the genetic determinants of disease HY Xiong, B Alipanahi, LJ Lee, H Bretschneider, D Merico, RKC Yuen, ... Science 347 (6218), 1254806, 2015 | 1425 | 2015 |
The Evolutionary Landscape of Alternative Splicing in Vertebrate Species NL Barbosa-Morais, M Irimia, Q Pan, HY Xiong, S Gueroussov, LJ Lee, ... Science 338 (6114), 1587-1593, 2012 | 1126 | 2012 |
Deep learning of the tissue-regulated splicing code MKK Leung, HY Xiong, LJ Lee, BJ Frey Bioinformatics 30 (12), i121-i129, 2014 | 610 | 2014 |
Bayesian prediction of tissue-regulated splicing using RNA sequence and cellular context HY Xiong, Y Barash, BJ Frey Bioinformatics 27 (18), 2554-2562, 2011 | 124 | 2011 |
Analysis and design of a differentially-fed frequency agile microstrip patch antenna SV Hum, HY Xiong IEEE Transactions on Antennas and Propagation 58 (10), 3122-3130, 2010 | 107 | 2010 |
Systems and methods for classifying, prioritizing and interpreting genetic variants and therapies using a deep neural network B Frey, MKK Leung, AT Delong, HY Xiong, B Alipanahi, LJ Lee, ... US Patent 10,185,803, 2019 | 102 | 2019 |
Correction of a splicing defect in a mouse model of congenital muscular dystrophy type 1A using a homology-directed-repair-independent mechanism DU Kemaladewi, E Maino, E Hyatt, H Hou, M Ding, KM Place, X Zhu, ... Nature medicine 23 (8), 984-989, 2017 | 88 | 2017 |
AVISPA: a web tool for the prediction and analysis of alternative splicing Y Barash, J Vaquero-Garcia, J González-Vallinas, HY Xiong, W Gao, ... Genome biology 14, 1-8, 2013 | 47 | 2013 |
System and method for training neural networks HY Xiong, A Delong, B Frey US Patent 10,410,118, 2019 | 46 | 2019 |
Challenges in estimating percent inclusion of alternatively spliced junctions from RNA-seq data B Kakaradov, HY Xiong, LJ Lee, N Jojic, BJ Frey BMC bioinformatics 13 (Suppl 6), S11, 2012 | 41 | 2012 |
System and method for training neural networks HY Xiong, A Delong, B Frey US Patent 10,885,435, 2021 | 4 | 2021 |
Probabilistic estimation of short sequence expression using RNA-Seq data and the “positional bootstrap” HY Xiong, LJ Lee, H Bretschneider, J Gao, N Jojic, BJ Frey bioRxiv, 046474, 2016 | 4 | 2016 |
Systems and methods for generating and training convolutional neural networks using biological sequences and relevance scores derived from structural, biochemical, population … HY Xiong, B Frey US Patent 11,636,920, 2023 | 3 | 2023 |
A differentially-fed microstrip patch antenna with enhanced frequency agility HY Xiong, SV Hum 2008 IEEE Antennas and Propagation Society International Symposium, 1-4, 2008 | 3 | 2008 |
Methods and systems for producing an expanded training set for machine learning using biological sequences BJ Frey, AT Delong, HY Xiong US Patent 11,769,073, 2023 | 1 | 2023 |
Making dropout invariant to transformations of activation functions and inputs J Ba, HY Xiong, B Frey NIPS 2014 Workshop on Deep Learning, 2014 | 1 | 2014 |
Systems and methods for classifying, prioritizing and interpreting genetic variants and therapies using a deep neural network B Frey, MKK Leung, AT Delong, HY Xiong, B Alipanahi, LJ Lee, ... US Patent 11,887,696, 2024 | | 2024 |
System and method for training neural networks HY Xiong, A Delong, B Frey US Patent 11,681,917, 2023 | | 2023 |
Systems and methods for classifying, prioritizing and interpreting genetic variants and therapies using a deep neural network B Frey, MKK Leung, AT Delong, HY Xiong, B Alipanahi, LJ Lee, ... US Patent App. 17/369,499, 2021 | | 2021 |
Inference and analysis of the human splicing code HY Xiong University of Toronto (Canada), 2016 | | 2016 |