Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia A Giustacchini, S Thongjuea, N Barkas, PS Woll, BJ Povinelli, CAG Booth, ... Nature medicine 23 (6), 692-702, 2017 | 412 | 2017 |
Stable knockdown of microRNA in vivo by lentiviral vectors B Gentner, G Schira, A Giustacchini, M Amendola, BD Brown, M Ponzoni, ... Nature methods 6 (1), 63-66, 2009 | 380 | 2009 |
Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo PS Woll, U Kjällquist, O Chowdhury, H Doolittle, DC Wedge, S Thongjuea, ... Cancer cell 25 (6), 794-808, 2014 | 362 | 2014 |
Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells A Grover, A Sanjuan-Pla, S Thongjuea, J Carrelha, A Giustacchini, ... Nature communications 7 (1), 11075, 2016 | 300 | 2016 |
Unravelling intratumoral heterogeneity through high-sensitivity single-cell mutational analysis and parallel RNA sequencing A Rodriguez-Meira, G Buck, SA Clark, BJ Povinelli, V Alcolea, E Louka, ... Molecular cell 73 (6), 1292-1305. e8, 2019 | 260 | 2019 |
Distinct myeloid progenitor–differentiation pathways identified through single-cell RNA sequencing R Drissen, N Buza-Vidas, P Woll, S Thongjuea, A Gambardella, ... Nature immunology 17 (6), 666-676, 2016 | 247 | 2016 |
Attenuation of miR-126 activity expands HSC in vivo without exhaustion ER Lechman, B Gentner, P van Galen, A Giustacchini, M Saini, ... Cell stem cell 11 (6), 799-811, 2012 | 234 | 2012 |
Identification of hematopoietic stem cell–specific miRNAs enables gene therapy of globoid cell leukodystrophy B Gentner, I Visigalli, H Hiramatsu, E Lechman, S Ungari, A Giustacchini, ... Science translational medicine 2 (58), 58ra84-58ra84, 2010 | 226 | 2010 |
Systemic and targeted delivery of semaphorin 3A inhibits tumor angiogenesis and progression in mouse tumor models A Casazza, X Fu, I Johansson, L Capparuccia, F Andersson, ... Arteriosclerosis, thrombosis, and vascular biology 31 (4), 741-749, 2011 | 144 | 2011 |
Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics AE Handel, S Chintawar, T Lalic, E Whiteley, J Vowles, A Giustacchini, ... Human molecular genetics 25 (5), 989-1000, 2016 | 116 | 2016 |
miRNA-126 orchestrates an oncogenic program in B cell precursor acute lymphoblastic leukemia S Nucera, A Giustacchini, F Boccalatte, A Calabria, C Fanciullo, T Plati, ... Cancer cell 29 (6), 905-921, 2016 | 73 | 2016 |
A dynamic niche provides Kit ligand in a stage-specific manner to the earliest thymocyte progenitors M Buono, R Facchini, S Matsuoka, S Thongjuea, D Waithe, TC Luis, ... Nature cell biology 18 (2), 157-167, 2016 | 73 | 2016 |
Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitors TC Luis, S Luc, T Mizukami, H Boukarabila, S Thongjuea, PS Woll, ... Nature immunology 17 (12), 1424-1435, 2016 | 64 | 2016 |
Ezh2 and Runx1 mutations collaborate to initiate lympho-myeloid leukemia in early thymic progenitors CAG Booth, N Barkas, WH Neo, H Boukarabila, EJ Soilleux, ... Cancer Cell 33 (2), 274-291. e8, 2018 | 60 | 2018 |
Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD–induced myeloproliferation AJ Mead, WH Neo, N Barkas, S Matsuoka, A Giustacchini, R Facchini, ... Journal of Experimental Medicine 214 (7), 2005-2021, 2017 | 55 | 2017 |
A double-switch vector system positively regulates transgene expression by endogenous microRNA expression (miR-ON vector) M Amendola, A Giustacchini, B Gentner, L Naldini Molecular Therapy 21 (5), 934-946, 2013 | 34 | 2013 |
Mbd3/NuRD controls lymphoid cell fate and inhibits tumorigenesis by repressing a B cell transcriptional program SJ Loughran, F Comoglio, FK Hamey, A Giustacchini, Y Errami, E Earp, ... Journal of Experimental Medicine 214 (10), 3085-3104, 2017 | 24 | 2017 |
Activation priming and cytokine polyfunctionality modulate the enhanced functionality of low-affinity CD19 CAR T cells IM Michelozzi, E Gomez-Castaneda, RVC Pohle, F Cardoso Rodriguez, ... Blood Advances 7 (9), 1725-1738, 2023 | 12 | 2023 |
Driving CAR T stem cell targeting in acute myeloid leukemia: The roads to success IM Michelozzi, E Kirtsios, A Giustacchini Cancers 13 (11), 2816, 2021 | 12 | 2021 |
Taming cell-to-cell heterogeneity in acute myeloid leukaemia with machine learning YE Sánchez-Corrales, RVC Pohle, S Castellano, A Giustacchini Frontiers in Oncology 11, 666829, 2021 | 8 | 2021 |