Phosphorylation of eIF2 Facilitates Ribosomal Bypass of an Inhibitory Upstream ORF to Enhance CHOP Translation*♦ LR Palam, TD Baird, RC Wek Journal of Biological Chemistry 286 (13), 10939-10949, 2011 | 507 | 2011 |
Phosphorylation of eIF2 directs ATF5 translational control in response to diverse stress conditions D Zhou, LR Palam, L Jiang, J Narasimhan, KA Staschke, RC Wek Journal of Biological Chemistry 283 (11), 7064-7073, 2008 | 347 | 2008 |
Inhibition of inflammatory signaling in Tet2 mutant preleukemic cells mitigates stress-induced abnormalities and clonal hematopoiesis Z Cai, JJ Kotzin, B Ramdas, S Chen, S Nelanuthala, LR Palam, R Pandey, ... Cell stem cell 23 (6), 833-849. e5, 2018 | 308 | 2018 |
Both transcriptional regulation and translational control of ATF4 are central to the integrated stress response S Dey, TD Baird, D Zhou, LR Palam, DF Spandau, RC Wek Journal of Biological Chemistry 285 (43), 33165-33174, 2010 | 280 | 2010 |
Integration of general amino acid control and target of rapamycin (TOR) regulatory pathways in nitrogen assimilation in yeast KA Staschke, S Dey, JM Zaborske, LR Palam, JN McClintick, T Pan, ... Journal of Biological Chemistry 285 (22), 16893-16911, 2010 | 145 | 2010 |
Selective mRNA translation during eIF2 phosphorylation induces expression of IBTKα TD Baird, LR Palam, ME Fusakio, JA Willy, CM Davis, JN McClintick, ... Molecular biology of the cell 25 (10), 1686-1697, 2014 | 133 | 2014 |
Integrated stress response is critical for gemcitabine resistance in pancreatic ductal adenocarcinoma LR Palam, J Gore, KE Craven, JL Wilson, M Korc Cell death & disease 6 (10), e1913-e1913, 2015 | 123 | 2015 |
Blimp1 prevents methylation of Foxp3 and loss of regulatory T cell identity at sites of inflammation G Garg, A Muschaweckh, H Moreno, A Vasanthakumar, S Floess, ... Cell reports 26 (7), 1854-1868. e5, 2019 | 114 | 2019 |
Ribosome elongation stall directs gene-specific translation in the integrated stress response SK Young, LR Palam, C Wu, MS Sachs, RC Wek Journal of Biological Chemistry 291 (12), 6546-6558, 2016 | 74 | 2016 |
Pancreatic cancer–associated retinoblastoma 1 dysfunction enables TGF-β to promote proliferation AJ Gore, SL Deitz, LR Palam, KE Craven, M Korc The Journal of clinical investigation 124 (1), 338-352, 2014 | 74 | 2014 |
Strobilocercus fasciolaris infection with hepatic sarcoma and gastroenteropathy in a Wistar colony JM Kumar, PL Reddy, V Aparna, G Srinivas, P Nagarajan, R Venkatesan, ... Veterinary Parasitology 141 (3-4), 362-367, 2006 | 58 | 2006 |
Physical and functional interaction between ribosomal protein L11 and the tumor suppressor ARF MS Dai, KB Challagundla, XX Sun, LR Palam, SX Zeng, RC Wek, H Lu Journal of Biological Chemistry 287 (21), 17120-17129, 2012 | 40 | 2012 |
Obesity-induced inflammation exacerbates clonal hematopoiesis SK Pasupuleti, B Ramdas, SS Burns, LR Palam, R Kanumuri, R Kumar, ... The Journal of Clinical Investigation 133 (11), 2023 | 33 | 2023 |
Loss of epigenetic regulator TET2 and oncogenic KIT regulate myeloid cell transformation via PI3K pathway LR Palam, RS Mali, B Ramdas, SN Srivatsan, V Visconte, RV Tiu, ... JCI insight 3 (4), 2018 | 23 | 2018 |
DNA Methyltransferase Protein Synthesis Is Reduced in CXXC Finger Protein 1–Deficient Embryonic Stem Cells JS Butler, LR Palam, CM Tate, JR Sanford, RC Wek, DG Skalnik DNA and cell biology 28 (5), 223-231, 2009 | 21 | 2009 |
Driver mutations in leukemia promote disease pathogenesis through a combination of cell-autonomous and niche modulation B Ramdas, RS Mali, LR Palam, R Pandey, Z Cai, SK Pasupuleti, ... Stem cell reports 15 (1), 95-109, 2020 | 14 | 2020 |
Physioxia-induced downregulation of Tet2 in hematopoietic stem cells contributes to enhanced self-renewal A Aljoufi, C Zhang, J Ropa, W Chang, LR Palam, S Cooper, B Ramdas, ... Blood, The Journal of the American Society of Hematology 140 (11), 1263-1277, 2022 | 9 | 2022 |
Potential clinical use of azacitidine and MEK inhibitor combination therapy in PTPN11-mutated juvenile myelomonocytic leukemia SK Pasupuleti, K Chao, B Ramdas, R Kanumuri, LR Palam, S Liu, J Wan, ... Molecular Therapy 31 (4), 986-1001, 2023 | 5 | 2023 |
Inhibition of BTK and PI3Kδ impairs the development of human JMML stem and progenitor cells B Ramdas, LD Yuen, LR Palam, R Patel, SK Pasupuleti, V Jideonwo, ... Molecular Therapy 30 (7), 2505-2521, 2022 | 4 | 2022 |
Loss of Dnmt3a impairs hematopoietic homeostasis and myeloid cell skewing via the PI3Kinase pathway LR Palam, B Ramdas, K Pickerell, SK Pasupuleti, R Kanumuri, ... JCI insight 8 (9), 2023 | 3 | 2023 |