Progesterone receptor induces ErbB-2 nuclear translocation to promote breast cancer growth via a novel transcriptional effect: ErbB-2 function as a coactivator of Stat3 W Béguelin, MC Díaz Flaqué, CJ Proietti, F Cayrol, MA Rivas, M Tkach, ... Molecular and cellular biology 30 (23), 5456-5472, 2010 | 115 | 2010 |
p42/p44 MAPK-mediated Stat3 Ser727 phosphorylation is required for progestin-induced full activation of Stat3 and breast cancer growth M Tkach, C Rosemblit, MA Rivas, CJ Proietti Anastasi, MC Díaz Flaqué, ... Bioscientifica, 2013 | 99 | 2013 |
Integrin αvβ3 acting as membrane receptor for thyroid hormones mediates angiogenesis in malignant T cells F Cayrol, MC Díaz Flaqué, T Fernando, SN Yang, HA Sterle, ... Blood, The Journal of the American Society of Hematology 125 (5), 841-851, 2015 | 95 | 2015 |
Stat3 regulates ErbB-2 expression and co-opts ErbB-2 nuclear function to induce miR-21 expression, PDCD4 downregulation and breast cancer metastasis L Venturutti, LV Romero, AJ Urtreger, MF Chervo, RI Cordo Russo, ... Oncogene 35 (17), 2208-2222, 2016 | 75 | 2016 |
Activation of Stat3 by heregulin/ErbB-2 through the co-option of progesterone receptor signaling drives breast cancer growth CJ Proietti, C Rosemblit, W Beguelin, MA Rivas, MC Díaz Flaqué, ... Molecular and cellular biology 29 (5), 1249-1265, 2009 | 73 | 2009 |
Targeting ErbB-2 nuclear localization and function inhibits breast cancer growth and overcomes trastuzumab resistance RI Cordo Russo, W Beguelin, D Flaqué, CJ Proietti, L Venturutti, ... Oncogene 34 (26), 3413-3428, 2015 | 61 | 2015 |
Targeting Stat3 induces senescence in tumor cells and elicits prophylactic and therapeutic immune responses against breast cancer growth mediated by NK cells and CD4+ T cells M Tkach, L Coria, C Rosemblit, MA Rivas, CJ Proietti, MC Díaz Flaqué, ... The Journal of Immunology 189 (3), 1162-1172, 2012 | 55 | 2012 |
Progesterone receptor assembly of a transcriptional complex along with activator protein 1, signal transducer and activator of transcription 3 and ErbB-2 governs breast cancer … MC Diaz Flaque, NM Galigniana, W Béguelin, R Vicario, CJ Proietti, ... Breast Cancer Research 15, 1-24, 2013 | 46 | 2013 |
Clinical relevance of ErbB-2/HER2 nuclear expression in breast cancer R Schillaci, P Guzmán, F Cayrol, W Beguelin, MC Díaz Flaqué, CJ Proietti, ... BMC cancer 12, 1-13, 2012 | 45 | 2012 |
Progestin drives breast cancer growth by inducing p21CIP1 expression through the assembly of a transcriptional complex among Stat3, progesterone receptor and ErbB-2 MCD Flaqué, R Vicario, CJ Proietti, F Izzo, R Schillaci, PV Elizalde Steroids 78 (6), 559-567, 2013 | 32 | 2013 |
Novel role of signal transducer and activator of transcription 3 as a progesterone receptor coactivator in breast cancer CJ Proietti, W Béguelin, MCD Flaqué, F Cayrol, MA Rivas, M Tkach, ... Steroids 76 (4), 381-392, 2011 | 31 | 2011 |
Non-genomic actions of thyroid hormones regulate the growth and angiogenesis of T cell lymphomas F Cayrol, HA Sterle, MC Díaz Flaqué, ML Barreiro Arcos, GA Cremaschi Frontiers in Endocrinology 10, 63, 2019 | 29 | 2019 |
Thyroid status modulates T lymphoma growth via cell cycle regulatory proteins and angiogenesis HA Sterle, E Valli, MF Cayrol, MA Paulazo, DJ Martinel Lamas, ... BioScientifica, 2014 | 28 | 2014 |
The thyroid status reprograms T cell lymphoma growth and modulates immune cell frequencies HA Sterle, ML Barreiro Arcos, E Valli, MA Paulazo, SP Mendez Huergo, ... Journal of Molecular Medicine 94, 417-429, 2016 | 23 | 2016 |
Induction of apoptosis in T lymphoma cells by long-term treatment with thyroxine involves PKCζ nitration by nitric oxide synthase ML Barreiro Arcos, HA Sterle, C Vercelli, E Valli, MF Cayrol, AJ Klecha, ... Apoptosis 18, 1376-1390, 2013 | 20 | 2013 |
Thyroid hormones and their membrane receptors as therapeutic targets for T cell lymphomas GA Cremaschi, F Cayrol, HA Sterle, MCD Flaqué, MLB Arcos Pharmacological Research 109, 55-63, 2016 | 17 | 2016 |
Heregulin co-opts PR transcriptional action via Stat3 role as a coregulator to drive cancer growth CJ Proietti, F Izzo, MC Díaz Flaqué, R Cordo Russo, L Venturutti, ... Molecular Endocrinology 29 (10), 1468-1485, 2015 | 14 | 2015 |
Thyroid status regulates the tumor microenvironment delineating breast cancer fate HA Sterle, X Hildebrandt, MV Álvarez, MA Paulazo, LM Gutierrez, ... Endocrine-Related Cancer 28 (7), 403-418, 2021 | 11 | 2021 |
Thyroid hormones induce doxorubicin chemosensitivity through enzymes involved in chemotherapy metabolism in lymphoma T cells MCD Flaqué, MF Cayrol, HA Sterle, M del Rosario Aschero, JAD Albuja, ... Oncotarget 10 (32), 3051, 2019 | 7 | 2019 |
Inhibition of integrin αVβ3 signaling improves the antineoplastic effect of bexarotene in cutaneous T-cell lymphoma F Cayrol, MV Revuelta, M Debernardi, A Paulazo, JM Phillip, N Zamponi, ... Molecular cancer therapeutics 21 (9), 1485-1496, 2022 | 2 | 2022 |