Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase SE Ewald, A Engel, J Lee, M Wang, M Bogyo, GM Barton The Journal of experimental medicine 208 (4), 643-651, 2011 | 362 | 2011 |
Target deconvolution techniques in modern phenotypic profiling J Lee, M Bogyo Current opinion in chemical biology 17 (1), 118-126, 2013 | 201 | 2013 |
N-(3-acyloxy-2-benzylpropyl)-N'-[4-(methylsulfonylamino) benzyl] thiourea analogues: novel potent and high affinity antagonists and partial antagonists of the vanilloid receptor J Lee, J Lee, M Kang, M Shin, JM Kim, SU Kang, JO Lim, HK Choi, ... Journal of medicinal chemistry 46 (14), 3116-3126, 2003 | 168 | 2003 |
Functional imaging of legumain in cancer using a new quenched activity-based probe LE Edgington, M Verdoes, A Ortega, NP Withana, J Lee, S Syed, ... Journal of the American Chemical Society 135 (1), 174-182, 2013 | 167 | 2013 |
High affinity antagonists of the vanilloid receptor Y Wang, T Szabo, JD Welter, A Toth, R Tran, J Lee, SU Kang, YG Suh, ... Molecular pharmacology 62 (4), 947-956, 2002 | 129 | 2002 |
Development of near-infrared fluorophore (NIRF)-labeled activity-based probes for in vivo imaging of legumain J Lee, M Bogyo ACS chemical biology 5 (2), 233-243, 2010 | 98 | 2010 |
Targeted inhibition of Snail family zinc finger transcription factors by oligonucleotide-Co (III) Schiff base conjugate AS Harney, J Lee, LM Manus, P Wang, DM Ballweg, C LaBonne, ... Proceedings of the National Academy of Sciences 106 (33), 13667-13672, 2009 | 97 | 2009 |
Anti-tumor promoting potential of naturally occurring diarylheptanoids structurally related to curcumin KS Chun, Y Sohn, HS Kim, OH Kim, KK Park, JM Lee, J Lee, JY Lee, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 428 (1 …, 1999 | 94 | 1999 |
A steroid-conjugated contrast agent for magnetic resonance imaging of cell signaling J Lee, MJ Zylka, DJ Anderson, JE Burdette, TK Woodruff, TJ Meade Journal of the American Chemical Society 127 (38), 13164-13166, 2005 | 79 | 2005 |
N-(3-Acyloxy-2-benzylpropyl)-N′-(4-hydroxy-3-methoxybenzyl) thiourea derivatives as potent vanilloid receptor agonists and analgesics J Lee, J Lee, J Kim, SY Kim, MW Chun, H Cho, SW Hwang, U Oh, ... Bioorganic & medicinal chemistry 9 (1), 19-32, 2001 | 74 | 2001 |
Recent advances in organelle-targeted fluorescent probes NE Choi, JY Lee, EC Park, JH Lee, J Lee Molecules 26 (1), 217, 2021 | 56 | 2021 |
Effect of side chain hydrophobicity and cationic charge on antimicrobial activity and cytotoxicity of helical peptoids J Lee, D Kang, J Choi, W Huang, M Wadman, AE Barron, J Seo Bioorganic & medicinal chemistry letters 28 (2), 170-173, 2018 | 51 | 2018 |
Synthesis and Biological Evaluation of Aryloxazole Derivatives as Antimitotic and Vascular-Disrupting Agents for Cancer Therapy MJ Choi, ES No, DA Thorat, JW Jang, H Yang, J Lee, H Choo, SJ Kim, ... Journal of medicinal chemistry 56 (22), 9008-9018, 2013 | 51 | 2013 |
Rational design, synthesis, and biological evaluation of progesterone-modified MRI contrast agents J Lee, JE Burdette, KW MacRenaris, D Mustafi, TK Woodruff, TJ Meade Chemistry & biology 14 (7), 824-834, 2007 | 49 | 2007 |
Mitochondrion-Targeting Peptides and Peptidomimetics: Recent Progress and Design Principles S Kim, HY Nam, J Lee, J Seo Biochemistry 59 (3), 270-284, 2019 | 45 | 2019 |
Discovery of Potent Human Glutaminyl Cyclase Inhibitors as Anti-Alzheimer’s Agents Based on Rational Design VH Hoang, PT Tran, M Cui, VTH Ngo, J Ann, J Park, J Lee, K Choi, H Cho, ... Journal of Medicinal Chemistry 60 (6), 2573-2590, 2017 | 45 | 2017 |
High-affinity partial agonists of the vanilloid receptor Y Wang, A Toth, R Tran, T Szabo, JD Welter, PM Blumberg, J Lee, ... Molecular pharmacology 64 (2), 325-333, 2003 | 44 | 2003 |
Novel quinazoline-urea analogues as modulators for Aβ-induced mitochondrial dysfunction: Design, synthesis, and molecular docking study A Elkamhawy, J Lee, BG Park, I Park, AN Pae, EJ Roh European journal of medicinal chemistry 84, 466-475, 2014 | 41 | 2014 |
Structure–activity relationship of human glutaminyl cyclase inhibitors having an N-(5-methyl-1H-imidazol-1-yl) propyl thiourea template PT Tran, VH Hoang, SA Thorat, SE Kim, J Ann, YJ Chang, DW Nam, ... Bioorganic & medicinal chemistry 21 (13), 3821-3830, 2013 | 40 | 2013 |
Discovery of an Orally Bioavailable Benzofuran Analogue That Serves as a β-Amyloid Aggregation Inhibitor for the Potential Treatment of Alzheimer’s Disease HJ Ha, DW Kang, HM Kim, JM Kang, J Ann, HJ Hyun, JH Lee, SH Kim, ... Journal of medicinal chemistry, 2017 | 39 | 2017 |