ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death M Raab, M Gentili, H de Belly, HR Thiam, P Vargas, AJ Jimenez, ... Science 352 (6283), 359-362, 2016 | 862 | 2016 |
Inherited STING-activating mutation underlies a familial inflammatory syndrome with lupus-like manifestations N Jeremiah, B Neven, M Gentili, I Callebaut, S Maschalidi, ... The Journal of clinical investigation 124 (12), 5516-5520, 2014 | 517 | 2014 |
The capsids of HIV-1 and HIV-2 determine immune detection of the viral cDNA by the innate sensor cGAS in dendritic cells X Lahaye, T Satoh, M Gentili, S Cerboni, C Conrad, I Hurbain, A El Marjou, ... Immunity 39 (6), 1132-1142, 2013 | 432 | 2013 |
Transmission of innate immune signaling by packaging of cGAMP in viral particles M Gentili, J Kowal, M Tkach, T Satoh, X Lahaye, C Conrad, M Boyron, ... Science 349 (6253), 1232-1236, 2015 | 310 | 2015 |
The N-terminal domain of cGAS determines preferential association with centromeric DNA and innate immune activation in the nucleus M Gentili, X Lahaye, F Nadalin, GPF Nader, EP Lombardi, S Herve, ... Cell reports 26 (9), 2377-2393. e13, 2019 | 233 | 2019 |
Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes S Cerboni, N Jeremiah, M Gentili, U Gehrmann, C Conrad, ... Journal of Experimental Medicine 214 (6), 1769-1785, 2017 | 232 | 2017 |
Longitudinal proteomic analysis of severe COVID-19 reveals survival-associated signatures, tissue-specific cell death, and cell-cell interactions MR Filbin, A Mehta, AM Schneider, KR Kays, JR Guess, M Gentili, ... Cell Reports Medicine 2 (5), 2021 | 204 | 2021 |
NONO detects the nuclear HIV capsid to promote cGAS-mediated innate immune activation X Lahaye, M Gentili, A Silvin, C Conrad, L Picard, M Jouve, E Zueva, ... Cell 175 (2), 488-501. e22, 2018 | 203 | 2018 |
Compromised nuclear envelope integrity drives TREX1-dependent DNA damage and tumor cell invasion GP de Freitas Nader, S Agüera-Gonzalez, F Routet, M Gratia, M Maurin, ... Cell 184 (20), 5230-5246. e22, 2021 | 137 | 2021 |
SARS-CoV-2 hijacks folate and one-carbon metabolism for viral replication Y Zhang, R Guo, SH Kim, H Shah, S Zhang, JH Liang, Y Fang, M Gentili, ... Nature communications 12 (1), 1676, 2021 | 135 | 2021 |
SARS-CoV-2 viremia is associated with distinct proteomic pathways and predicts COVID-19 outcomes Y Li, AM Schneider, A Mehta, M Sade-Feldman, KR Kays, M Gentili, ... The Journal of clinical investigation 131 (13), 2021 | 118 | 2021 |
Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs S Weingarten-Gabbay, S Klaeger, S Sarkizova, LR Pearlman, DY Chen, ... Cell 184 (15), 3962-3980. e17, 2021 | 112 | 2021 |
Diversity of pathogen sensors in dendritic cells S Cerboni, M Gentili, N Manel Advances in immunology 120, 211-237, 2013 | 59 | 2013 |
Human STING is a proton channel B Liu, RJ Carlson, IS Pires, M Gentili, E Feng, Q Hellier, MA Schwartz, ... Science 381 (6657), 508-514, 2023 | 53 | 2023 |
A cell-free nanobody engineering platform rapidly generates SARS-CoV-2 neutralizing nanobodies X Chen, M Gentili, N Hacohen, A Regev Nature communications 12 (1), 5506, 2021 | 53 | 2021 |
Nuclear envelope protein SUN2 promotes cyclophilin-A-dependent steps of HIV replication X Lahaye, T Satoh, M Gentili, S Cerboni, A Silvin, C Conrad, ... Cell reports 15 (4), 879-892, 2016 | 49 | 2016 |
Sensing of HIV-1 entry triggers a type I interferon response in human primary macrophages J Decalf, M Desdouits, V Rodrigues, FX Gobert, M Gentili, ... Journal of virology 91 (15), 10.1128/jvi. 00147-17, 2017 | 47 | 2017 |
Plasma proteomics reveals tissue-specific cell death and mediators of cell-cell interactions in severe COVID-19 patients MR Filbin, A Mehta, AM Schneider, KR Kays, JR Guess, M Gentili, ... BioRxiv, 2020.11. 02.365536, 2020 | 44 | 2020 |
ESCRT-dependent STING degradation inhibits steady-state and cGAMP-induced signalling M Gentili, B Liu, M Papanastasiou, D Dele-Oni, MA Schwartz, RJ Carlson, ... Nature Communications 14 (1), 611, 2023 | 37 | 2023 |
Prioritization of autoimmune disease-associated genetic variants that perturb regulatory element activity in T cells K Mouri, MH Guo, CG de Boer, MM Lissner, IA Harten, GA Newby, ... Nature genetics 54 (5), 603-612, 2022 | 36 | 2022 |