An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma C Neftel, J Laffy, MG Filbin, T Hara, ME Shore, GJ Rahme, AR Richman, ... Cell 178 (4), 835-849. e21, 2019 | 1796 | 2019 |
Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq MG Filbin, I Tirosh, V Hovestadt, MKL Shaw, LE Escalante, ... Science 360 (6386), 331-335, 2018 | 567 | 2018 |
Tenascin-C and SF/HGF produced by myofibroblasts in vitro provide convergent pro-invasive signals to human colon cancer cells through RhoA and Rac O De Wever, QD Nguyen, L Van Hoorde, M Bracke, E Bruyneel, ... The FASEB journal 18 (9), 1016-1018, 2004 | 464 | 2004 |
Nuclear bodies and compartments: functional roles and cellular signalling in health and disease A Zimber, QD Nguyen, C Gespach Cellular signalling 16 (10), 1085-1104, 2004 | 201 | 2004 |
Positron emission tomography imaging of drug-induced tumor apoptosis with a caspase-3/7 specific [18F]-labeled isatin sulfonamide QD Nguyen, G Smith, M Glaser, M Perumal, E Årstad, EO Aboagye Proceedings of the National Academy of Sciences 106 (38), 16375-16380, 2009 | 192 | 2009 |
Design, synthesis, and biological characterization of a caspase 3/7 selective isatin labeled with 2-[18F] fluoroethylazide G Smith, M Glaser, M Perumal, QD Nguyen, B Shan, E Årstad, ... Journal of medicinal chemistry 51 (24), 8057-8067, 2008 | 176 | 2008 |
Trefoil peptides as proangiogenic factors in vivo and in vitro: implication of cyclooxygenase‐2 and EGF receptor signaling S Rodrigues, E Van Aken, S Van Bocxlaer, S Attoub, QD Nguyen, ... The FASEB journal 17 (1), 7-16, 2003 | 176 | 2003 |
Trefoil peptides as proangiogenic factors in vivo and in vitro: implication of cyclooxygenase‐2 and EGF receptor signaling S Rodrigues, E Van Aken, S Van Bocxlaer, S Attoub, QD Nguyen, ... The FASEB journal 17 (1), 7-16, 2003 | 176 | 2003 |
CXCR4‐Targeted and MMP‐Responsive Iron Oxide Nanoparticles for Enhanced Magnetic Resonance Imaging J Gallo, N Kamaly, I Lavdas, E Stevens, QD Nguyen, ... Angewandte Chemie International Edition 53 (36), 9550-9554, 2014 | 172 | 2014 |
Cells Lacking the RB1 Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival MG Oser, R Fonseca, AA Chakraborty, R Brough, A Spektor, RB Jennings, ... Cancer discovery 9 (2), 230-247, 2019 | 144 | 2019 |
Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG JN Anastas, BM Zee, JH Kalin, M Kim, R Guo, S Alexandrescu, MA Blanco, ... Cancer Cell 36 (5), 528-544. e10, 2019 | 143 | 2019 |
Synthetic lethal and resistance interactions with BET bromodomain inhibitors in triple-negative breast cancer S Shu, HJ Wu, YG Jennifer, R Zeid, IS Harris, B Jovanović, K Murphy, ... Molecular cell 78 (6), 1096-1113. e8, 2020 | 140 | 2020 |
Reactivating HIF prolyl hydroxylases under hypoxia results in metabolic catastrophe and cell death DA Tennant, C Frezza, ED MacKenzie, QD Nguyen, L Zheng, MA Selak, ... Oncogene 28 (45), 4009-4021, 2009 | 138 | 2009 |
Heterogeneity in Lung 18FDG Uptake in Pulmonary Arterial Hypertension Potential of Dynamic 18FDG Positron Emission Tomography With Kinetic Analysis as a Bridging Biomarker for … L Zhao, A Ashek, L Wang, W Fang, S Dabral, O Dubois, J Cupitt, ... Circulation 128 (11), 1214-1224, 2013 | 125 | 2013 |
Combination inhibition of PI3K and mTORC1 yields durable remissions in mice bearing orthotopic patient-derived xenografts of HER2-positive breast cancer brain metastases J Ni, SH Ramkissoon, S Xie, S Goel, DG Stover, H Guo, V Luu, E Marco, ... Nature medicine 22 (7), 723-726, 2016 | 121 | 2016 |
Concurrent dexamethasone limits the clinical benefit of immune checkpoint blockade in glioblastoma JB Iorgulescu, PC Gokhale, MC Speranza, BK Eschle, MJ Poitras, ... Clinical Cancer Research 27 (1), 276-287, 2021 | 118 | 2021 |
Activation of cellular invasion by trefoil peptides and src is mediated by cyclooxygenase-and thromboxane A2 receptor-dependent signaling pathways S RODRIGUES, QDÉ NGUYEN, S FAIVRE, E Bruyneel, L THIM, ... The FASEB Journal 15 (9), 1517-1528, 2001 | 116 | 2001 |
A novel small molecule hydroxamate preferentially inhibits HDAC6 activity and tumour growth M Kaliszczak, S Trousil, O Åberg, M Perumal, QD Nguyen, EO Aboagye British journal of cancer 108 (2), 342-350, 2013 | 111 | 2013 |
A bioorthogonal 68 Ga-labelling strategy for rapid in vivo imaging HL Evans, QD Nguyen, LS Carroll, M Kaliszczak, FJ Twyman, AC Spivey, ... Chemical Communications 50 (67), 9557-9560, 2014 | 91 | 2014 |
The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis MG Oser, AH Sabet, W Gao, AA Chakraborty, AC Schinzel, RB Jennings, ... Genes & development 33 (23-24), 1718-1738, 2019 | 85 | 2019 |