Pharmacology and structure‐activity relationships of bioactive polycyclic cage compounds: a focus on pentacycloundecane derivatives WJ Geldenhuys, SF Malan, JR Bloomquist, AP Marchand, ... Medicinal research reviews 25 (1), 21-48, 2005 | 241 | 2005 |
Preparation and physicochemical characterization of 5 niclosamide solvates and 1 hemisolvate EC Van Tonder, MD Mahlatji, SF Malan, W Liebenberg, MR Caira, ... Aaps Pharmscitech 5, 86-95, 2004 | 154 | 2004 |
Synthesis and evaluation of 7-substituted coumarin derivatives as multimodal monoamine oxidase-B and cholinesterase inhibitors for the treatment of Alzheimer's disease J Joubert, GB Foka, BP Repsold, DW Oliver, E Kapp, SF Malan European journal of medicinal chemistry 125, 853-864, 2017 | 122 | 2017 |
Inhibition of monoamine oxidase by 8-benzyloxycaffeine analogues B Strydom, SF Malan, N Castagnoli Jr, JJ Bergh, JP Petzer Bioorganic & medicinal chemistry 18 (3), 1018-1028, 2010 | 112 | 2010 |
Indazole derivatives and their therapeutic applications: a patent review (2013-2017) I Denya, SF Malan, J Joubert Expert opinion on therapeutic patents 28 (6), 441-453, 2018 | 111 | 2018 |
Polycyclic cage structures as lipophilic scaffolds for neuroactive drugs J Joubert, WJ Geldenhuys, CJ Van der Schyf, DW Oliver, HG Kruger, ... ChemMedChem 7 (3), 375-384, 2012 | 105 | 2012 |
Propargylamine as functional moiety in the design of multifunctional drugs for neurodegenerative disorders: MAO inhibition and beyond FT Zindo, J Joubert, SF Malan Future medicinal chemistry 7 (5), 609-629, 2015 | 103 | 2015 |
Inhibition of monoamine oxidase B by selected benzimidazole and caffeine analogues D van den Berg, KR Zoellner, MO Ogunrombi, SF Malan, G Terre’Blanche, ... Bioorganic & medicinal chemistry 15 (11), 3692-3702, 2007 | 93 | 2007 |
Inhibition of monoamine oxidase B by analogues of the adenosine A2A receptor antagonist (E)-8-(3-chlorostyryl) caffeine (CSC) N Vlok, SF Malan, N Castagnoli Jr, JJ Bergh, JP Petzer Bioorganic & medicinal chemistry 14 (10), 3512-3521, 2006 | 87 | 2006 |
Synthesis and biological evaluation of pentacyclo [5.4. 0.02, 6.03, 10.05, 9] undecane derivatives as potential therapeutic agents in Parkinson's disease WJ Geldenhuys, SF Malan, T Murugesan, CJ Van der Schyf, ... Bioorganic & medicinal chemistry 12 (7), 1799-1806, 2004 | 86 | 2004 |
Dual inhibition of monoamine oxidase B and antagonism of the adenosine A2A receptor by (E, E)-8-(4-phenylbutadien-1-yl) caffeine analogues J Pretorius, SF Malan, N Castagnoli Jr, JJ Bergh, JP Petzer Bioorganic & medicinal chemistry 16 (18), 8676-8684, 2008 | 85 | 2008 |
Inhibition of monoamine oxidase by indole and benzofuran derivatives LHA Prins, JP Petzer, SF Malan European Journal of Medicinal Chemistry 45 (10), 4458-4466, 2010 | 80 | 2010 |
Role of monoamine oxidase, nitric oxide synthase and regional brain monoamines in the antidepressant-like effects of methylene blue and selected structural analogues BH Harvey, I Duvenhage, F Viljoen, N Scheepers, SF Malan, G Wegener, ... Biochemical pharmacology 80 (10), 1580-1591, 2010 | 76 | 2010 |
Medicinal chemistry of polycyclic cage compounds in drug discovery research DW Oliver, SF Malan Medicinal Chemistry Research 17, 137-151, 2008 | 71 | 2008 |
Structure–activity relationships of pentacycloundecylamines at the N-methyl-d-aspartate receptor WJ Geldenhuys, SF Malan, JR Bloomquist, CJ Van der Schyf Bioorganic & medicinal chemistry 15 (3), 1525-1532, 2007 | 70 | 2007 |
Antioxidant properties of 4-quinolones and structurally related flavones J Greeff, J Joubert, SF Malan, S van Dyk Bioorganic & medicinal chemistry 20 (2), 809-818, 2012 | 69 | 2012 |
Anti-inflammatory activity and QSAR studies of compounds isolated from Hyacinthaceae species and Tachiadenus longiflorus Griseb.(Gentianaceae) K du Toit, EE Elgorashi, SF Malan, SE Drewes, J van Staden, NR Crouch, ... Bioorganic & medicinal chemistry 13 (7), 2561-2568, 2005 | 63 | 2005 |
Physicochemical prediction of a brain–blood distribution profile in polycyclic amines J Zah, G Terre'Blanche, E Erasmus, SF Malan Bioorganic & medicinal chemistry 11 (17), 3569-3578, 2003 | 58 | 2003 |
Quantitative structure–activity relationship studies on acetylcholinesterase enzyme inhibitory effects of Amaryllidaceae alkaloids EE Elgorashi, SF Malan, GI Stafford, J Van Staden South African Journal of Botany 72 (2), 224-231, 2006 | 56 | 2006 |
Inhibition of monoamine oxidase by (E)-styrylisatin analogues EM Van der Walt, EM Milczek, SF Malan, DE Edmondson, N Castagnoli Jr, ... Bioorganic & medicinal chemistry letters 19 (9), 2509-2513, 2009 | 55 | 2009 |