ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation G D’Uva, A Aharonov, M Lauriola, D Kain, Y Yahalom-Ronen, S Carvalho, ... Nature cell biology 17 (5), 627-638, 2015 | 651 | 2015 |
The extracellular matrix protein agrin promotes heart regeneration in mice E Bassat, YE Mutlak, A Genzelinakh, IY Shadrin, K Baruch Umansky, ... Nature 547 (7662), 179-184, 2017 | 577 | 2017 |
Proapoptotic BID is an ATM effector in the DNA-damage response I Kamer, R Sarig, Y Zaltsman, H Niv, G Oberkovitz, L Regev, G Haimovich, ... Cell 122 (4), 593-603, 2005 | 282 | 2005 |
p53 plays a role in mesenchymal differentiation programs, in a cell fate dependent manner A Molchadsky, I Shats, N Goldfinger, M Pevsner-Fischer, M Olson, ... PloS one 3 (11), e3707, 2008 | 217 | 2008 |
tBID Homooligomerizes in the mitochondrial membrane to induce apoptosis M Grinberg, R Sarig, Y Zaltsman, D Frumkin, N Grammatikakis, ... Journal of Biological Chemistry 277 (14), 12237-12245, 2002 | 215 | 2002 |
p53 is balancing development, differentiation and de-differentiation to assure cancer prevention A Molchadsky, N Rivlin, R Brosh, V Rotter, R Sarig Carcinogenesis 31 (9), 1501-1508, 2010 | 205 | 2010 |
Mutant p53 facilitates somatic cell reprogramming and augments the malignant potential of reprogrammed cells R Sarig, N Rivlin, R Brosh, C Bornstein, I Kamer, O Ezra, A Molchadsky, ... Journal of Experimental Medicine 207 (10), 2127-2140, 2010 | 176 | 2010 |
Targeted inactivation of dystrophin gene product Dp71: phenotypic impact in mouse retina C Dalloz, R Sarig, P Fort, D Yaffe, A Bordais, T Pannicke, J Grosche, ... Human Molecular Genetics 12 (13), 1543-1554, 2003 | 161 | 2003 |
Reduced matrix rigidity promotes neonatal cardiomyocyte dedifferentiation, proliferation and clonal expansion Y Yahalom-Ronen, D Rajchman, R Sarig, B Geiger, E Tzahor Elife 4, e07455, 2015 | 144 | 2015 |
Targeted inactivation of Dp71, the major non-muscle product of the DMD gene: differential activity of the Dp71 promoter during development R Sarig, V Mezger-Lallemand, I Gitelman, C Davis, O Fuchs, D Yaffe, ... Human Molecular Genetics 8 (1), 1-10, 1999 | 131 | 1999 |
p53 is required for brown adipogenic differentiation and has a protective role against diet-induced obesity A Molchadsky, O Ezra, PG Amendola, D Krantz, I Kogan-Sakin, ... Cell Death & Differentiation 20 (5), 774-783, 2013 | 125 | 2013 |
p53 coordinates cranial neural crest cell growth and epithelial-mesenchymal transition/delamination processes A Rinon, A Molchadsky, E Nathan, G Yovel, V Rotter, R Sarig, E Tzahor Development 138 (9), 1827-1838, 2011 | 116 | 2011 |
Regeneration and transdifferentiation potential of muscle‐derived stem cells propagated as myospheres R Sarig, Z Baruchi, O Fuchs, U Nudel, D Yaffe Stem cells 24 (7), 1769-1778, 2006 | 115 | 2006 |
BID-D59A is a potent inducer of apoptosis in primary embryonic fibroblasts R Sarig, Y Zaltsman, RC Marcellus, R Flavell, TW Mak, A Gross Journal of Biological Chemistry 278 (12), 10707-10715, 2003 | 90 | 2003 |
Transient p53-mediated regenerative senescence in the injured heart R Sarig, R Rimmer, E Bassat, L Zhang, KB Umansky, D Lendengolts, ... Circulation 139 (21), 2491-2494, 2019 | 65 | 2019 |
p53 counteracts reprogramming by inhibiting mesenchymal-to-epithelial transition R Brosh, Y Assia-Alroy, A Molchadsky, C Bornstein, E Dekel, S Madar, ... Cell Death & Differentiation 20 (2), 312-320, 2013 | 64 | 2013 |
SPATA18, a spermatogenesis-associated gene, is a novel transcriptional target of p53 and p63 C Bornstein, R Brosh, A Molchadsky, S Madar, I Kogan-Sakin, I Goldstein, ... Molecular and cellular biology, 2011 | 55 | 2011 |
p53‐dependent transcriptional regulation of EDA2R and its involvement in chemotherapy‐induced hair loss R Brosh, R Sarig, EB Natan, A Molchadsky, S Madar, C Bornstein, ... FEBS letters 584 (11), 2473-2477, 2010 | 49 | 2010 |
The onset of p53 loss of heterozygosity is differentially induced in various stem cell types and may involve the loss of either allele Y Shetzer, S Kagan, G Koifman, R Sarig, I Kogan-Sakin, M Charni, ... Cell Death & Differentiation 21 (9), 1419-1431, 2014 | 42 | 2014 |
Nanog inhibits the switch of myogenic cells towards the osteogenic lineage BS Kochupurakkal, R Sarig, O Fuchs, D Piestun, G Rechavi, D Givol Biochemical and biophysical research communications 365 (4), 846-850, 2008 | 27 | 2008 |