Extracellular M. tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway RO Watson, PS Manzanillo, JS Cox Cell 150 (4), 803-815, 2012 | 824 | 2012 |
The cytosolic sensor cGAS detects Mycobacterium tuberculosis DNA to induce type I interferons and activate autophagy RO Watson, SL Bell, DA MacDuff, JM Kimmey, EJ Diner, J Olivas, ... Cell host & microbe 17 (6), 811-819, 2015 | 609 | 2015 |
The ubiquitin ligase parkin mediates resistance to intracellular pathogens PS Manzanillo, JS Ayres, RO Watson, AC Collins, G Souza, CS Rae, ... Nature 501 (7468), 512-516, 2013 | 561 | 2013 |
Unique Features of a Highly Pathogenic Campylobacter jejuni Strain D Hofreuter, J Tsai, RO Watson, V Novik, B Altman, M Benitez, C Clark, ... Infection and immunity 74 (8), 4694-4707, 2006 | 402 | 2006 |
A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1 B Zhao, F Du, P Xu, C Shu, B Sankaran, SL Bell, M Liu, Y Lei, X Gao, X Fu, ... Nature 569 (7758), 718-722, 2019 | 280 | 2019 |
Campylobacter jejuni survives within epithelial cells by avoiding delivery to lysosomes RO Watson, JE Galán PLoS pathogens 4 (1), e14, 2008 | 225 | 2008 |
Role of tyrosine kinases and the tyrosine phosphatase SptP in the interaction of Salmonella with host cells S Murli, RO Watson, JE Galán Cellular microbiology 3 (12), 795-810, 2001 | 178 | 2001 |
Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis CG Weindel, EL Martinez, X Zhao, CJ Mabry, SL Bell, KJ Vail, ... Cell 185 (17), 3214-3231. e23, 2022 | 144 | 2022 |
Signal transduction in Campylobacter jejuni‐induced cytokine production RO Watson, JE Galán Cellular microbiology 7 (5), 655-665, 2005 | 127 | 2005 |
LRRK2 maintains mitochondrial homeostasis and regulates innate immune responses to Mycobacterium tuberculosis CG Weindel, SL Bell, KJ Vail, KO West, KL Patrick, RO Watson Elife 9, e51071, 2020 | 97 | 2020 |
A MyD88-Deficient Mouse Model Reveals a Role for Nramp1 in Campylobacter jejuni Infection RO Watson, V Novik, D Hofreuter, M Lara-Tejero, JE Galán Infection and immunity 75 (4), 1994-2003, 2007 | 93 | 2007 |
Exploring the “multiple-hit hypothesis” of neurodegenerative disease: bacterial infection comes up to bat KL Patrick, SL Bell, CG Weindel, RO Watson Frontiers in Cellular and Infection Microbiology 9, 138, 2019 | 86 | 2019 |
The splicing factor hnRNP M is a critical regulator of innate immune gene expression in macrophages KO West, HM Scott, S Torres-Odio, AP West, KL Patrick, RO Watson Cell reports 29 (6), 1594-1609. e5, 2019 | 70 | 2019 |
Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice Y Lei, C Guerra Martinez, S Torres-Odio, SL Bell, CE Birdwell, JD Bryant, ... Science advances 7 (22), eabe7548, 2021 | 66 | 2021 |
Identification of Rgg-Regulated Exoproteins ofStreptococcus pyogenes MS Chaussee, RO Watson, JC Smoot, JM Musser Infection and immunity 69 (2), 822-831, 2001 | 64 | 2001 |
Rgg Influences the Expression of Multiple Regulatory Loci To Coregulate Virulence Factor Expression in Streptococcus pyogenes MS Chaussee, GL Sylva, DE Sturdevant, LM Smoot, MR Graham, ... Infection and immunity 70 (2), 762-770, 2002 | 58 | 2002 |
Sexual dimorphism in campylobacteriosis NJC Strachan, RO Watson, V Novik, D Hofreuter, ID Ogden, JE Galan Epidemiology & Infection 136 (11), 1492-1495, 2008 | 51 | 2008 |
Galectin-8 Senses Phagosomal Damage and Recruits Selective Autophagy Adapter TAX1BP1 To Control Mycobacterium tuberculosis Infection in Macrophages SL Bell, KL Lopez, JS Cox, KL Patrick, RO Watson MBio 12 (4), 10.1128/mbio. 01871-20, 2021 | 49 | 2021 |
TRIM14 is a key regulator of the type I IFN response during Mycobacterium tuberculosis infection CT Hoffpauir, SL Bell, KO West, T Jing, AR Wagner, S Torres-Odio, ... The Journal of Immunology 205 (1), 153-167, 2020 | 43 | 2020 |
For better or worse: cytosolic DNA sensing during intracellular bacterial infection induces potent innate immune responses KL Patrick, SL Bell, RO Watson Journal of molecular biology 428 (17), 3372-3386, 2016 | 25 | 2016 |